Sex difference in human olfactory sensitivity is associated with plasma adiponectin.
Fasting
Food restriction
Ghrelin
Gut hormones
Odour threshold
Journal
Hormones and behavior
ISSN: 1095-6867
Titre abrégé: Horm Behav
Pays: United States
ID NLM: 0217764
Informations de publication
Date de publication:
09 2022
09 2022
Historique:
received:
31
03
2022
revised:
04
07
2022
accepted:
05
07
2022
pubmed:
23
7
2022
medline:
5
10
2022
entrez:
22
7
2022
Statut:
ppublish
Résumé
Energy deprivation as well as hormones that regulate appetite and eating can influence olfactory function. This study investigated olfactory sensitivity for a food-related and a non-food odour prior to and after a meal, and its relationship to the energy-regulating hormones ghrelin and adiponectin. The olfactory sensitivity for orange and rose (PEA) odour in healthy, normal-weight volunteers (19 women, 45 men, 1 undisclosed individual) was not affected by the consumption of a meal. Olfactory sensitivity was not associated with concentrations of circulating ghrelin. However, olfactory sensitivity was higher for women than for men, indicating better olfactory performance. This difference between women and men was related to concentrations of plasma adiponectin, an adipose-specific hormone. Adiponectin may thus explain why sex differences in olfactory sensitivity emerge, and may also account for some of the inconsistencies in previous findings on sex differences. Our findings add to the limited literature on the impact of stomach and adipose tissue-derived hormones on olfactory sensitivity. Further studies are needed to establish a causal link between circulating adiponectin and a sex difference in olfactory sensitivity.
Identifiants
pubmed: 35868172
pii: S0018-506X(22)00129-5
doi: 10.1016/j.yhbeh.2022.105235
pii:
doi:
Substances chimiques
Adiponectin
0
Ghrelin
0
Leptin
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
105235Informations de copyright
Copyright © 2022 The Author(s). Published by Elsevier Inc. All rights reserved.