Effects of pramipexole on beta-amyloid
Acetylcholinesterase
/ metabolism
Adenosine Triphosphate
/ metabolism
Alzheimer Disease
/ metabolism
Amyloid beta-Peptides
/ metabolism
Animals
Antioxidants
/ pharmacology
Biomarkers
/ metabolism
Cytochromes
/ metabolism
Glutathione
/ metabolism
Hippocampus
Maze Learning
Memory Disorders
/ chemically induced
Mitochondria
Oxidative Stress
Peptide Fragments
Pramipexole
/ adverse effects
Rats
Rats, Wistar
Reactive Oxygen Species
/ metabolism
bcl-2-Associated X Protein
/ metabolism
Alzheimer’s disease
Mitochondrial dysfunction
Oxidative phosphorylation
Oxidative stress
Pramipexole
Journal
Neurotoxicology
ISSN: 1872-9711
Titre abrégé: Neurotoxicology
Pays: Netherlands
ID NLM: 7905589
Informations de publication
Date de publication:
09 2022
09 2022
Historique:
received:
20
11
2021
revised:
12
07
2022
accepted:
13
07
2022
pubmed:
23
7
2022
medline:
21
9
2022
entrez:
22
7
2022
Statut:
ppublish
Résumé
Oxidative damage and mitochondrial dysfunction are two prominent pathological features and gradually understood as important pathogenic events for neurodegenerative diseases, including aging and Alzheimer's disease (AD). The present study was aimed to explore the prolonged treatment of pramipexole (PPX) following amyloid beta (Aβ
Identifiants
pubmed: 35868426
pii: S0161-813X(22)00121-8
doi: 10.1016/j.neuro.2022.07.006
pii:
doi:
Substances chimiques
Amyloid beta-Peptides
0
Antioxidants
0
Biomarkers
0
Cytochromes
0
Peptide Fragments
0
Reactive Oxygen Species
0
amyloid beta-protein (1-42)
0
bcl-2-Associated X Protein
0
Pramipexole
83619PEU5T
Adenosine Triphosphate
8L70Q75FXE
Acetylcholinesterase
EC 3.1.1.7
Glutathione
GAN16C9B8O
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
91-101Informations de copyright
Copyright © 2022 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.