Comparing radiolytic production of H

Animals Zebrafish Proton Therapy Electrons Protons Hydrogen Peroxide Radiotherapy Dosage
Electron FLASH Hydrogen peroxyde Proton FLASH Zebrafish embryos

Journal

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
ISSN: 1879-0887
Titre abrégé: Radiother Oncol
Pays: Ireland
ID NLM: 8407192

Informations de publication

Date de publication:
10 2022
Historique:
received: 25 04 2022
revised: 30 06 2022
accepted: 13 07 2022
pubmed: 23 7 2022
medline: 21 10 2022
entrez: 22 7 2022
Statut: ppublish

Résumé

The physico-chemical and biological response to conventional and UHDR electron and proton beams was investigated, along with conventional photons. The temporal structure and nature of the beam affected both, with electron beam at ≥1400 Gy/s and proton beam at 0.1 and 1260 Gy/s found to be isoefficient at sparing zebrafish embryos.

Identifiants

DOI: 10.1016/j.radonc.2022.07.011 PMID: 35868604
pubmed: 35868604
pii: S0167-8140(22)04207-4
doi: 10.1016/j.radonc.2022.07.011
pii:
doi:

Substances chimiques

Protons 0
Hydrogen Peroxide BBX060AN9V

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

197-202

Subventions

Organisme : NCI NIH HHS
ID : P01 CA244091
Pays : United States

Informations de copyright

Copyright © 2022 The Authors. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: [The proton studies were funded by a research grant from Varian, a Healthineers company (Palo Alto, CA, USA) (to MCV, SP and TL).]

Auteurs

Houda Kacem (H)

Radiation Oncology Laboratory, Service of Radiation Oncology, Department of Oncology. Lausanne, University Hospital and University of Lausanne, Switzerland.

Serena Psoroulas (S)

Paul Scherrer Institut-Centre for Proton Therapy, Villigen, Switzerland.

Gael Boivin (G)

Varian, a Siemens Healthineers Company, 3120 Hansen Way, Palo Alto, CA 94304, United States.

Michael Folkerts (M)

Varian, a Siemens Healthineers Company, 3120 Hansen Way, Palo Alto, CA 94304, United States.

Veljko Grilj (V)

Institute of Radiation Physics, University Hospital and University of Lausanne, Switzerland.

Tony Lomax (T)

Paul Scherrer Institut-Centre for Proton Therapy, Villigen, Switzerland; Institute of Radiation Physics, University Hospital and University of Lausanne, Switzerland.

Adrien Martinotti (A)

Radiation Oncology Laboratory, Service of Radiation Oncology, Department of Oncology. Lausanne, University Hospital and University of Lausanne, Switzerland.

David Meer (D)

Paul Scherrer Institut-Centre for Proton Therapy, Villigen, Switzerland.

Jonathan Ollivier (J)

Radiation Oncology Laboratory, Service of Radiation Oncology, Department of Oncology. Lausanne, University Hospital and University of Lausanne, Switzerland.

Benoit Petit (B)

Radiation Oncology Laboratory, Service of Radiation Oncology, Department of Oncology. Lausanne, University Hospital and University of Lausanne, Switzerland.

Sairos Safai (S)

Paul Scherrer Institut-Centre for Proton Therapy, Villigen, Switzerland.

Ricky A Sharma (RA)

Varian, a Siemens Healthineers Company, 3120 Hansen Way, Palo Alto, CA 94304, United States.

Michele Togno (M)

Paul Scherrer Institut-Centre for Proton Therapy, Villigen, Switzerland.

Marta Vilalta (M)

Varian, a Siemens Healthineers Company, 3120 Hansen Way, Palo Alto, CA 94304, United States.

Damien C Weber (DC)

Paul Scherrer Institut-Centre for Proton Therapy, Villigen, Switzerland.

Marie-Catherine Vozenin (MC)

Radiation Oncology Laboratory, Service of Radiation Oncology, Department of Oncology. Lausanne, University Hospital and University of Lausanne, Switzerland. Electronic address: marie-catherine.vozenin@chuv.ch.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Comparing radiolytic production of H
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Poissons › Cypriniformes › Cyprinidae › Danio zébré › Comparing radiolytic production of H
questionsmedicales.fr › Thérapeutique › Radiothérapie › Radiothérapie par ions lourds › Protonthérapie › Comparing radiolytic production of H
questionsmedicales.fr › Phénomènes physiques › Phénomènes magnétiques › Phénomènes électromagnétiques › Électrons › Comparing radiolytic production of H
questionsmedicales.fr › Phénomènes physiques › Particules élémentaires › Nucléons › Protons › Comparing radiolytic production of H
questionsmedicales.fr › Composés chimiques organiques › Radicaux libres › Peroxydes › Peroxyde d'hydrogène › Comparing radiolytic production of H
questionsmedicales.fr › Thérapeutique › Radiothérapie › Dosimétrie en radiothérapie › Comparing radiolytic production of H