A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells.
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
22 07 2022
22 07 2022
Historique:
received:
20
02
2019
accepted:
06
06
2022
entrez:
22
7
2022
pubmed:
23
7
2022
medline:
27
7
2022
Statut:
epublish
Résumé
Glucose-induced insulin secretion depends on β-cell electrical activity. Inhibition of ATP-regulated potassium (K
Identifiants
pubmed: 35869052
doi: 10.1038/s41467-022-31103-y
pii: 10.1038/s41467-022-31103-y
pmc: PMC9307633
doi:
Substances chimiques
Insulin
0
Ion Channels
0
PIEZO1 protein, human
0
Piezo1 protein, mouse
0
Adenosine Triphosphate
8L70Q75FXE
Glucose
IY9XDZ35W2
Calcium
SY7Q814VUP
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
4237Subventions
Organisme : Medical Research Council
ID : MR/T002107/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/V011979/1
Pays : United Kingdom
Informations de copyright
© 2022. The Author(s).
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