1,3-Dichloro-2-propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes.
1,3-dichloro-2-propanol
HepG2 cells
Nrf2/ARE
ferroptosis
mice
Journal
Environmental toxicology
ISSN: 1522-7278
Titre abrégé: Environ Toxicol
Pays: United States
ID NLM: 100885357
Informations de publication
Date de publication:
Oct 2022
Oct 2022
Historique:
revised:
16
06
2022
received:
02
04
2022
accepted:
03
07
2022
pubmed:
24
7
2022
medline:
14
9
2022
entrez:
23
7
2022
Statut:
ppublish
Résumé
1,3-Dichloro-2-propanol (1,3-DCP) is a representative chloropropane environmental contaminant with multiple toxicities. Ferroptosis is a novel iron-dependent form of regulated cell death that is closely associated with the accumulation of lipid peroxides, Fe
Substances chimiques
NF-E2-Related Factor 2
0
1,3-dichloro-2-propanol
0F4P2VQC07
alpha-Chlorohydrin
96-24-2
Iron
E1UOL152H7
Carboxylic Ester Hydrolases
EC 3.1.1.-
arylesterase
EC 3.1.1.2
Glutathione
GAN16C9B8O
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2515-2528Subventions
Organisme : National Natural Science Foundation of China
Informations de copyright
© 2022 Wiley Periodicals LLC.
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