Rhabdomyolysis and myoglobinuria following single induction dose of propofol in a dog.
creatine kinase
glycosuria
myoglobinuria
rhabdomyolysis
Journal
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
ISSN: 1476-4431
Titre abrégé: J Vet Emerg Crit Care (San Antonio)
Pays: United States
ID NLM: 101152804
Informations de publication
Date de publication:
Jan 2023
Jan 2023
Historique:
revised:
06
05
2021
received:
28
10
2020
accepted:
11
06
2021
pubmed:
24
7
2022
medline:
25
1
2023
entrez:
23
7
2022
Statut:
ppublish
Résumé
To report a case of rhabdomyolysis and myoglobinuria following single induction dose of propofol in a dog. A 5-year-old intact male Shih-Tzu dog was presented for pigmenturia occurring a few hours following anesthesia for comprehensive oral health assessment and treatment. After premedication with IV diazepam (0.5 mg/kg), anesthesia was induced with IV propofol (4 mg/kg) and maintained with isoflurane vaporized in oxygen. A few hours following recovery from anesthesia, the dog developed rhabdomyolysis and myoglobinuria associated with increased serum alanine aminotransferase and C-reactive protein concentrations, as well as mild hypokalemia and euglycemic glycosuria. Approximately 48 hours after IV fluid therapy, the dog was clinically normal, and myoglobinuria progressively resolved. This is the first case description of rhabdomyolysis and myoglobinuria following a single dose of injectable propofol.
Substances chimiques
Propofol
YI7VU623SF
Diazepam
Q3JTX2Q7TU
Isoflurane
CYS9AKD70P
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
118-122Informations de copyright
© Veterinary Emergency and Critical Care Society 2022.
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