Flavonoid Intake From Cocoa-Based Products and Adiposity Parameters in Adolescents in Spain.

(poly)phenols cardiometabolic catechin epicatechin obesity proanthocyanidins

Journal

Frontiers in nutrition
ISSN: 2296-861X
Titre abrégé: Front Nutr
Pays: Switzerland
ID NLM: 101642264

Informations de publication

Date de publication:
2022
Historique:
received: 28 04 2022
accepted: 08 06 2022
entrez: 25 7 2022
pubmed: 26 7 2022
medline: 26 7 2022
Statut: epublish

Résumé

Cocoa-based products are a good source of flavonoids, which may have beneficial effects on metabolic health. The aim of this study is to assess the relationship between flavonoids from cocoa-based products and adiposity parameters in adolescents. A cross-sectional study was conducted involving 944 adolescents aged 11-14 years enrolled in the SI! Program for Secondary Schools trial in Spain with available baseline data from food frequency questionnaires and anthropometric measurements [weight, height, waist circumference (WC), and fat mass percentage (% FM) by bioimpedance analysis]. Fat mass index (FMI) and waist-to-height ratio (WHtR) were obtained by dividing fat mass by height and WC by height, respectively. Body mass index (BMI), WC, and FMI for age and gender z-score were calculated. Overweight/obesity was defined as BMI ≥ 85th percentile and excess adiposity as %FM or FMI ≥ 75th percentile. WC ≥ 90th percentile and WHtR with a 0.5 threshold were considered as criteria of abdominal obesity. Multilevel mixed-effect regressions were used to evaluate the association between flavonoids from cocoa-based products and adiposity parameters. Municipalities and schools were considered random effects. Participants with a higher flavonoid intake from cocoa-based products had lower WC z-score [B = -0.04, 95% CI (-0.07; -0.01), A higher intake of flavonoids from cocoa-based products was associated with lower adiposity parameters and a lower probability of presenting abdominal obesity.

Sections du résumé

Background UNASSIGNED
Cocoa-based products are a good source of flavonoids, which may have beneficial effects on metabolic health.
Objective UNASSIGNED
The aim of this study is to assess the relationship between flavonoids from cocoa-based products and adiposity parameters in adolescents.
Methods UNASSIGNED
A cross-sectional study was conducted involving 944 adolescents aged 11-14 years enrolled in the SI! Program for Secondary Schools trial in Spain with available baseline data from food frequency questionnaires and anthropometric measurements [weight, height, waist circumference (WC), and fat mass percentage (% FM) by bioimpedance analysis]. Fat mass index (FMI) and waist-to-height ratio (WHtR) were obtained by dividing fat mass by height and WC by height, respectively. Body mass index (BMI), WC, and FMI for age and gender z-score were calculated. Overweight/obesity was defined as BMI ≥ 85th percentile and excess adiposity as %FM or FMI ≥ 75th percentile. WC ≥ 90th percentile and WHtR with a 0.5 threshold were considered as criteria of abdominal obesity. Multilevel mixed-effect regressions were used to evaluate the association between flavonoids from cocoa-based products and adiposity parameters. Municipalities and schools were considered random effects.
Results UNASSIGNED
Participants with a higher flavonoid intake from cocoa-based products had lower WC z-score [B = -0.04, 95% CI (-0.07; -0.01),
Conclusions UNASSIGNED
A higher intake of flavonoids from cocoa-based products was associated with lower adiposity parameters and a lower probability of presenting abdominal obesity.

Identifiants

pubmed: 35873437
doi: 10.3389/fnut.2022.931171
pmc: PMC9298534
doi:

Types de publication

Journal Article

Langues

eng

Pagination

931171

Informations de copyright

Copyright © 2022 Laveriano-Santos, Arancibia-Riveros, Tresserra-Rimbau, Castro-Barquero, Ruiz-León, Estruch, Casas, Bodega, de Miguel, de Cos-Gandoy, Martínez-Gómez, Rodríguez, Santos-Beneit, Fernández-Alvira, Fernández-Jiménez and Lamuela-Raventós.

Déclaration de conflit d'intérêts

RL-R reports receiving lecture fees from Cerveceros de España and receiving lecture fees and travel support from Adventia and Idilia Foods SL. RE reports grants from Fundación Dieta Mediterránea, Spain, Cerveza y Salud, Spain, personal fees for given lectures from Brewers of Europe, Belgium, Fundación Cerveza y Salud, Spain, Pernaud-Ricard, Mexico, Instituto Cervantes, Alburquerque, USA, Instituto Cervantes, Milan, Italy, Instituto Cervantes, Tokyo, Japan, Lilly Laboratories, Spain, Wine and Culinary International Forum, Spain, non-financial support to organize a National Congress on Nutrition, and also feeding trials with products from Grand Fountain and Uriach Laboratories, Spain. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

Mol Nutr Food Res. 2014 Jan;58(1):33-48
pubmed: 24259381
Curr Opin Pharmacol. 2006 Dec;6(6):580-5
pubmed: 16973420
J Agric Food Chem. 2008 May 14;56(9):3111-7
pubmed: 18412367
J Nutr. 2011 Nov;141(11):1982-8
pubmed: 21956956
J Am Coll Cardiol. 2018 Dec 25;72(25):3310-3319
pubmed: 30527619
J Nutr. 2000 Nov;130(11):2733-8
pubmed: 11053514
Biofactors. 2008;33(3):211-23
pubmed: 19478425
Crit Rev Food Sci Nutr. 2014;54(11):1458-72
pubmed: 24580540
Am J Clin Nutr. 2017 Mar;105(3):626-634
pubmed: 28100511
Clin Endocrinol (Oxf). 2013 Nov;79(5):667-74
pubmed: 23469930
Crit Rev Food Sci Nutr. 2019;59(15):2349-2362
pubmed: 29553824
Br J Nutr. 2010 Jun;103(12):1808-16
pubmed: 20102675
Pediatr Obes. 2016 Apr;11(2):120-7
pubmed: 25893950
J Nutr. 2016 Nov;146(11):2325-2333
pubmed: 27683874
Am Heart J. 2019 Sep;215:27-40
pubmed: 31277052
Am J Med. 2020 Sep;133(9):1082-1087
pubmed: 32067980
Database (Oxford). 2013 Oct 07;2013:bat070
pubmed: 24103452
Nat Rev Endocrinol. 2013 Jan;9(1):13-27
pubmed: 23165161
Eur J Pharmacol. 2014 Apr 5;728:24-30
pubmed: 24491839
Database (Oxford). 2010;2010:bap024
pubmed: 20428313
J Sports Sci Med. 2007 Dec 01;6(4):505-18
pubmed: 24149485
Int J Obes (Lond). 2005 Sep;29 Suppl 2:S66-77
pubmed: 16385756
Front Nutr. 2021 Dec 13;8:749007
pubmed: 34966768
Am J Clin Nutr. 2005 Jan;81(1 Suppl):230S-242S
pubmed: 15640486
PeerJ. 2017 May 17;5:e3304
pubmed: 28533962
JAMA Pediatr. 2020 Jun 1;174(6):609-617
pubmed: 32202626
Food Funct. 2019 May 22;10(5):2958-2969
pubmed: 31073569
Crit Rev Food Sci Nutr. 2022;62(2):475-489
pubmed: 32942899
Nutrition. 2014 Feb;30(2):236-9
pubmed: 24139727
Am J Clin Nutr. 2013 Jul;98(1):49-56
pubmed: 23697708
J Chromatogr A. 2009 Oct 23;1216(43):7258-67
pubmed: 19671472
Obes Facts. 2013;6(2):165-75
pubmed: 23594424
Br J Sports Med. 2020 Dec;54(24):1451-1462
pubmed: 33239350
Natl Health Stat Report. 2011 Nov 9;(43):1-7
pubmed: 22164513
Int J Obes (Lond). 2005 Oct;29(10):1175-83
pubmed: 16030519
Natl Health Stat Report. 2013 Feb 11;(63):1-3
pubmed: 24992748
Nutrients. 2020 Sep 30;12(10):
pubmed: 33007981
Food Funct. 2020 Apr 30;11(4):3441-3450
pubmed: 32236212
Br J Nutr. 2016 Apr;115(8):1439-52
pubmed: 26888046
Circulation. 2013 Oct 8;128(15):1689-712
pubmed: 24016455
Br J Nutr. 2020 Dec 14;124(11):1198-1206
pubmed: 32475366
Am J Clin Nutr. 1997 Apr;65(4 Suppl):1220S-1228S; discussion 1229S-1231S
pubmed: 9094926
Arch Dis Child. 1976 Mar;51(3):170-9
pubmed: 952550
Nutrients. 2021 Mar 16;13(3):
pubmed: 33809476
Nutrients. 2021 May 12;13(5):
pubmed: 34066238
Pediatr Res. 2015 Dec;78(6):723-9
pubmed: 26331767
J Agric Food Chem. 2019 Apr 3;67(13):3605-3614
pubmed: 30855143
Pediatrics. 2002 Jan;109(1):45-60
pubmed: 11773541
Int J Obes (Lond). 2006 Jun;30(6):988-92
pubmed: 16432546
Public Health Nutr. 2006 Dec;9(8):1045-54
pubmed: 17125569
Eur J Nutr. 2020 Mar;59(2):801-812
pubmed: 30903362

Auteurs

Emily P Laveriano-Santos (EP)

Department of Nutrition, Food Science and Gastronomy, School of Pharmacy and Food Sciences, XIA, Institute of Nutrition and Food Safety (INSA-UB), University of Barcelona, Barcelona, Spain.

Camila Arancibia-Riveros (C)

Department of Nutrition, Food Science and Gastronomy, School of Pharmacy and Food Sciences, XIA, Institute of Nutrition and Food Safety (INSA-UB), University of Barcelona, Barcelona, Spain.

Anna Tresserra-Rimbau (A)

Department of Nutrition, Food Science and Gastronomy, School of Pharmacy and Food Sciences, XIA, Institute of Nutrition and Food Safety (INSA-UB), University of Barcelona, Barcelona, Spain.
Consorcio CIBER, M.P. Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.

Sara Castro-Barquero (S)

Consorcio CIBER, M.P. Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
Department of Internal Medicine, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

Ana María Ruiz-León (AM)

Consorcio CIBER, M.P. Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
Department of Internal Medicine, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Mediterranean Diet Foundation, Barcelona, Spain.

Ramón Estruch (R)

Consorcio CIBER, M.P. Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
Department of Internal Medicine, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

Rosa Casas (R)

Consorcio CIBER, M.P. Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
Department of Internal Medicine, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

Patricia Bodega (P)

Foundation for Science, Health and Education (SHE), Barcelona, Spain.
Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.), Madrid, Spain.

Mercedes de Miguel (M)

Foundation for Science, Health and Education (SHE), Barcelona, Spain.
Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.), Madrid, Spain.

Amaya de Cos-Gandoy (A)

Foundation for Science, Health and Education (SHE), Barcelona, Spain.
Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.), Madrid, Spain.

Jesús Martínez-Gómez (J)

Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.), Madrid, Spain.

Carla Rodríguez (C)

Foundation for Science, Health and Education (SHE), Barcelona, Spain.

Gloria Santos-Beneit (G)

Foundation for Science, Health and Education (SHE), Barcelona, Spain.
The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

Juan M Fernández-Alvira (JM)

Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.), Madrid, Spain.

Rodrigo Fernández-Jiménez (R)

Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.), Madrid, Spain.
CIBER de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.
Department of Cardiology, Hospital Universitario Clínico San Carlos, Madrid, Spain.

Rosa M Lamuela-Raventós (RM)

Department of Nutrition, Food Science and Gastronomy, School of Pharmacy and Food Sciences, XIA, Institute of Nutrition and Food Safety (INSA-UB), University of Barcelona, Barcelona, Spain.
Consorcio CIBER, M.P. Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.

Classifications MeSH