Disseminated mucormycosis in a patient with severe COVID-19 on venovenous extracorporeal membrane oxygenation: A case report.

COVID-19 associated mucormycosis Invasive fungal infection Invasive mucormycosis Steroid

Journal

IDCases
ISSN: 2214-2509
Titre abrégé: IDCases
Pays: Netherlands
ID NLM: 101634540

Informations de publication

Date de publication:
2022
Historique:
received: 27 03 2022
revised: 18 07 2022
accepted: 18 07 2022
pubmed: 26 7 2022
medline: 26 7 2022
entrez: 25 7 2022
Statut: ppublish

Résumé

Since the global outbreak of coronavirus disease 2019 (COVID-19), there have been several reports of mucormycosis as a secondary complication. However, the disseminated type of mucormycosis is extremely rare. A 58-year-old male patient with COVID-19 started receiving venovenous extracorporeal membrane oxygenation because of severe respiratory failure. During hospitalization, intra-abdominal hemorrhage occurred and an emergency laparotomy was performed. Subsequently, the patient suffered septic shock, and part of the small intestines and the abdominal wall became necrotic. Finally, the patient died. At autopsy, he was diagnosed with disseminated mucormycosis. Disseminated mucormycosis should be considered in patients with COVID-19 with refractory sepsis unresponsive to broad-spectrum antimicrobial therapy.

Sections du résumé

Background UNASSIGNED
Since the global outbreak of coronavirus disease 2019 (COVID-19), there have been several reports of mucormycosis as a secondary complication. However, the disseminated type of mucormycosis is extremely rare.
Case UNASSIGNED
A 58-year-old male patient with COVID-19 started receiving venovenous extracorporeal membrane oxygenation because of severe respiratory failure. During hospitalization, intra-abdominal hemorrhage occurred and an emergency laparotomy was performed. Subsequently, the patient suffered septic shock, and part of the small intestines and the abdominal wall became necrotic. Finally, the patient died. At autopsy, he was diagnosed with disseminated mucormycosis.
Conclusion UNASSIGNED
Disseminated mucormycosis should be considered in patients with COVID-19 with refractory sepsis unresponsive to broad-spectrum antimicrobial therapy.

Identifiants

pubmed: 35874315
doi: 10.1016/j.idcr.2022.e01578
pii: S2214-2509(22)00206-2
pmc: PMC9295314
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e01578

Informations de copyright

© 2022 Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

There are no conflicts of interest to declare.

Auteurs

Hazuki Ito (H)

Department of Emergency Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Japan.

Ryuichiro Kakizaki (R)

Department of Emergency Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Japan.

Keisuke Harada (K)

Department of Emergency Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Japan.

Daisuke Kyuno (D)

Department of Pathology, Sapporo Medical University School of Medicine, South 1, West 17, Chuo-ku, Sapporo, Japan.

Terufumi Kubo (T)

Department of Pathology, Sapporo Medical University School of Medicine, South 1, West 17, Chuo-ku, Sapporo, Japan.

Naofumi Bunya (N)

Department of Emergency Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Japan.

Takehiko Kasai (T)

Department of Emergency Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Japan.

Shuji Uemura (S)

Department of Emergency Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Japan.

Eichi Narimatsu (E)

Department of Emergency Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Japan.

Classifications MeSH