MuSK-Myasthenia Gravis Unmasked by Hydroxychloroquine.
Journal
Case reports in medicine
ISSN: 1687-9627
Titre abrégé: Case Rep Med
Pays: United States
ID NLM: 101512910
Informations de publication
Date de publication:
2022
2022
Historique:
received:
04
02
2022
revised:
13
06
2022
accepted:
17
06
2022
entrez:
25
7
2022
pubmed:
26
7
2022
medline:
26
7
2022
Statut:
epublish
Résumé
Muscle-specific tyrosine kinase (MuSK) antibody positive myasthenia gravis (MuSK-MG) is a rare clinical disorder, and diagnosing it can be challenging. Most of the patients present with predominant facial, oculo-bulbar, and neck muscle weakness along with respiratory muscle involvement. Such a presentation can be mistaken for bulbar onset motor neuron disease or as one of the rare oculopharyngeal myopathies. This report proves that MuSK-MG can also be unmasked by HCQ administration. Awareness of drug-induced/-unmasked MG is important, as failure to do so may result in a severe morbidity and a fatal outcome. The offending drug has to be promptly discontinued, and appropriate treatment should be instituted.
Identifiants
pubmed: 35874444
doi: 10.1155/2022/4802538
pmc: PMC9307397
doi:
Types de publication
Case Reports
Langues
eng
Pagination
4802538Informations de copyright
Copyright © 2022 Shalini Bhaskar and Mohammed Fauzi Bin Abdul Rani.
Déclaration de conflit d'intérêts
The authors declare no conflicts of interest.
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