The function of Wtap in N
Journal
Nature immunology
ISSN: 1529-2916
Titre abrégé: Nat Immunol
Pays: United States
ID NLM: 100941354
Informations de publication
Date de publication:
08 2022
08 2022
Historique:
received:
05
11
2021
accepted:
13
06
2022
pubmed:
26
7
2022
medline:
10
8
2022
entrez:
25
7
2022
Statut:
ppublish
Résumé
T cell antigen-receptor (TCR) signaling controls the development, activation and survival of T cells by involving several layers and numerous mechanisms of gene regulation. N
Identifiants
pubmed: 35879451
doi: 10.1038/s41590-022-01268-1
pii: 10.1038/s41590-022-01268-1
doi:
Substances chimiques
Cell Cycle Proteins
0
RNA Splicing Factors
0
RNA, Messenger
0
N(6)-ribosyladenine
103960-10-7
Methyltransferases
EC 2.1.1.-
Adenosine
K72T3FS567
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1208-1221Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer Nature America, Inc.
Références
Daley, S. R., Teh, C., Hu, D. Y., Strasser, A. & Gray, D. H. D. Cell death and thymic tolerance. Immunol. Rev. 277, 9–20 (2017).
pubmed: 28462532
doi: 10.1111/imr.12532
Zhan, Y., Carrington, E. M., Zhang, Y., Heinzel, S. & Lew, A. M. Life and death of activated T cells: how are they different from naïve T cells? Front. Immunol. 8, 1809 (2017).
pubmed: 29326701
pmcid: 5733345
doi: 10.3389/fimmu.2017.01809
Pasparakis, M. & Vandenabeele, P. Necroptosis and its role in inflammation. Nature 517, 311–320 (2015).
pubmed: 25592536
doi: 10.1038/nature14191
Trebak, M. & Kinet, J. P. Calcium signalling in T cells. Nat. Rev. Immunol. 19, 154–169 (2019).
pubmed: 30622345
pmcid: 6788797
doi: 10.1038/s41577-018-0110-7
Feske, S. et al. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 441, 179–185 (2006).
pubmed: 16582901
doi: 10.1038/nature04702
Picard, C. et al. STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunity. N. Engl. J. Med. 360, 1971–1980 (2009).
pubmed: 19420366
pmcid: 2851618
doi: 10.1056/NEJMoa0900082
Lacruz, R. S. & Feske, S. Diseases caused by mutations in ORAI1 and STIM1. Ann. N.Y. Acad. Sci. 1356, 45–79 (2015).
pubmed: 26469693
pmcid: 4692058
doi: 10.1111/nyas.12938
Hogan, P. G., Chen, L., Nardone, J. & Rao, A. Transcriptional regulation by calcium, calcineurin, and NFAT. Genes Dev. 17, 2205–2232 (2003).
pubmed: 12975316
doi: 10.1101/gad.1102703
Xiao, S. et al. FasL promoter activation by IL-2 through SP1 and NFAT but not Egr-2 and Egr-3. Eur. J. Immunol. 29, 3456–3465 (1999).
pubmed: 10556800
doi: 10.1002/(SICI)1521-4141(199911)29:11<3456::AID-IMMU3456>3.0.CO;2-B
Rengarajan, J. et al. Sequential involvement of NFAT and Egr transcription factors in FasL regulation. Immunity 12, 293–300 (2000).
pubmed: 10755616
doi: 10.1016/S1074-7613(00)80182-X
Dzialo-Hatton, R., Milbrandt, J., Hockett, R. D. Jr. & Weaver, C. T. Differential expression of Fas ligand in Th1 and Th2 cells is regulated by early growth response gene and NF-AT family members. J. Immunol. 166, 4534–4542 (2001).
pubmed: 11254710
doi: 10.4049/jimmunol.166.7.4534
La Rovere, R. M., Roest, G., Bultynck, G. & Parys, J. B. Intracellular Ca
pubmed: 27157108
doi: 10.1016/j.ceca.2016.04.005
Kim, K. D. et al. ORAI1 deficiency impairs activated T cell death and enhances T cell survival. J. Immunol. 187, 3620–3630 (2011).
pubmed: 21873530
doi: 10.4049/jimmunol.1100847
Desvignes, L. et al. STIM1 controls T cell-mediated immune regulation and inflammation in chronic infection. J. Clin. Invest. 125, 2347–2362 (2015).
pubmed: 25938788
pmcid: 4518689
doi: 10.1172/JCI80273
Zaccara, S., Ries, R. J. & Jaffrey, S. R. Reading, writing and erasing mRNA methylation. Nat. Rev. Mol. Cell Biol. 20, 608–624 (2019).
pubmed: 31520073
doi: 10.1038/s41580-019-0168-5
Fu, Y., Dominissini, D., Rechavi, G. & He, C. Gene expression regulation mediated through reversible m
pubmed: 24662220
doi: 10.1038/nrg3724
Shulman, Z. & Stern-Ginossar, N. The RNA modification N
pubmed: 32284591
doi: 10.1038/s41590-020-0650-4
Gao, Y. et al. m
pubmed: 32497523
pmcid: 7408742
doi: 10.1016/j.immuni.2020.05.003
Li, H. B. et al. m
pubmed: 28792938
pmcid: 5729908
doi: 10.1038/nature23450
Tong, J. et al. m
pubmed: 29303144
pmcid: 5799823
doi: 10.1038/cr.2018.7
Yao, Y. et al. METTL3-dependent m
pubmed: 33637761
pmcid: 7910450
doi: 10.1038/s41467-021-21594-6
Grenov, A.C. et al. The germinal center reaction depends on RNA methylation and divergent functions of specific methyl readers. J. Exp. Med. 218, e20210360 (2021).
Sprent, J. & Surh, C. D. Writer’s block: preventing m
pubmed: 28925383
doi: 10.1038/icb.2017.67
Cao, G., Li, H. B., Yin, Z. & Flavell, R. A. Recent advances in dynamic m6A RNA modification. Open Biol. 6, 160003 (2016).
pubmed: 27249342
pmcid: 4852458
doi: 10.1098/rsob.160003
Zaccara, S. & Jaffrey, S. R. A unified model for the function of YTHDF proteins in regulating m
pubmed: 32492408
pmcid: 7508256
doi: 10.1016/j.cell.2020.05.012
Lasman, L. et al. Context-dependent functional compensation between Ythdf m
pubmed: 32943573
pmcid: 7528697
doi: 10.1101/gad.340695.120
Liu, J. et al. A METTL3-METTL14 complex mediates mammalian nuclear RNA N
pubmed: 24316715
doi: 10.1038/nchembio.1432
Wang, P., Doxtader, K. A. & Nam, Y. Structural basis for cooperative function of Mettl3 and Mettl14 methyltransferases. Mol. Cell 63, 306–317 (2016).
pubmed: 27373337
pmcid: 4958592
doi: 10.1016/j.molcel.2016.05.041
Schöller, E. et al. Interactions, localization, and phosphorylation of the m
pubmed: 29348140
pmcid: 5855951
doi: 10.1261/rna.064063.117
Knuckles, P. et al. Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m
pubmed: 29535189
pmcid: 5900714
doi: 10.1101/gad.309146.117
Yue, Y. et al. VIRMA mediates preferential m
pubmed: 29507755
pmcid: 5826926
doi: 10.1038/s41421-018-0019-0
Bawankar, P. et al. Hakai is required for stabilization of core components of the m
pubmed: 34145251
pmcid: 8213727
doi: 10.1038/s41467-021-23892-5
Ping, X. L. et al. Mammalian WTAP is a regulatory subunit of the RNA N
pubmed: 24407421
pmcid: 3915904
doi: 10.1038/cr.2014.3
Schwartz, S. et al. Perturbation of m
pubmed: 24981863
pmcid: 4142486
doi: 10.1016/j.celrep.2014.05.048
Lu, T. X. et al. A new model of spontaneous colitis in mice induced by deletion of an RNA m
pubmed: 32634481
pmcid: 7498954
doi: 10.1016/j.jcmgh.2020.07.001
Borland, K. et al. Production and application of stable isotope-labeled internal standards for RNA modification analysis. Genes 10, 26 (2019).
pmcid: 6356711
doi: 10.3390/genes10010026
Ohnmacht, C. et al. MUCOSAL IMMUNOLOGY. The microbiota regulates type 2 immunity through RORγt
pubmed: 26160380
doi: 10.1126/science.aac4263
Lin, Z. et al. Mettl3-/Mettl14-mediated mRNA N
pubmed: 28914256
pmcid: 5630681
doi: 10.1038/cr.2017.117
Kieper, W. C. et al. Recent immune status determines the source of antigens that drive homeostatic T cell expansion. J. Immunol. 174, 3158–3163 (2005).
pubmed: 15749843
doi: 10.4049/jimmunol.174.6.3158
Hoefig, K. P. et al. Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation. Nat. Commun. 12, 5208 (2021).
pubmed: 34471108
pmcid: 8410761
doi: 10.1038/s41467-021-25345-5
Körtel, N. et al. Deep and accurate detection of m6A RNA modifications using miCLIP2 and m6Aboost machine learning. Nucleic Acids Res. 49, e92 (2021).
pubmed: 34157120
pmcid: 8450095
doi: 10.1093/nar/gkab485
Buchbender, A. et al. Improved library preparation with the new iCLIP2 protocol. Methods 178, 33–48 (2020).
pubmed: 31610236
doi: 10.1016/j.ymeth.2019.10.003
Krakau, S., Richard, H. & Marsico, A. PureCLIP: capturing target-specific protein–RNA interaction footprints from single-nucleotide CLIP-seq data. Genome Biol. 18, 240 (2017).
pubmed: 29284540
pmcid: 5746957
doi: 10.1186/s13059-017-1364-2
Paris, J. et al. Targeting the RNA m
pubmed: 31031138
pmcid: 6617387
doi: 10.1016/j.stem.2019.03.021
Zhu, Y. et al. The E3 ligase VHL promotes follicular helper T cell differentiation via glycolytic-epigenetic control. J. Exp. Med. 216, 1664–1681 (2019).
pubmed: 31123085
pmcid: 6605754
doi: 10.1084/jem.20190337
Little, N. A., Hastie, N. D. & Davies, R. C. Identification of WTAP, a novel Wilms’ tumour 1-associating protein. Hum. Mol. Genet. 9, 2231–2239 (2000).
pubmed: 11001926
doi: 10.1093/oxfordjournals.hmg.a018914
Wang, X. et al. N
pubmed: 24284625
doi: 10.1038/nature12730
Vaeth, M., Kahlfuss, S. & Feske, S. CRAC channels and calcium signaling in T cell-mediated immunity. Trends Immunol. 41, 878–901 (2020).
pubmed: 32711944
pmcid: 7985820
doi: 10.1016/j.it.2020.06.012
Li, S. et al. The transcription factors Egr2 and Egr3 are essential for the control of inflammation and antigen-induced proliferation of B and T cells. Immunity 37, 685–696 (2012).
pubmed: 23021953
pmcid: 3477314
doi: 10.1016/j.immuni.2012.08.001
Tummers, B. & Green, D. R. Caspase-8: regulating life and death. Immunol. Rev. 277, 76–89 (2017).
pubmed: 28462525
pmcid: 5417704
doi: 10.1111/imr.12541
Lee, P. P. et al. A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity 15, 763–774 (2001).
pubmed: 11728338
doi: 10.1016/S1074-7613(01)00227-8
Sledzinska, A. et al. TGF-β signalling is required for CD4
pubmed: 24115907
pmcid: 3792861
doi: 10.1371/journal.pbio.1001674
Rubtsov, Y. P. et al. Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces. Immunity 28, 546–558 (2008).
pubmed: 18387831
doi: 10.1016/j.immuni.2008.02.017
Hogquist, K. A. et al. T cell receptor antagonist peptides induce positive selection. Cell 76, 17–27 (1994).
pubmed: 8287475
doi: 10.1016/0092-8674(94)90169-4
Barnden, M. J., Allison, J., Heath, W. R. & Carbone, F. R. Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements. Immunol. Cell Biol. 76, 34–40 (1998).
pubmed: 9553774
doi: 10.1046/j.1440-1711.1998.00709.x
Busch, A., Brüggemann, M., Ebersberger, S. & Zarnack, K. iCLIP data analysis: a complete pipeline from sequencing reads to RBP binding sites. Methods 178, 49–62 (2020).
pubmed: 31751605
doi: 10.1016/j.ymeth.2019.11.008
Bray, N. L., Pimentel, H., Melsted, P. & Pachter, L. Near-optimal probabilistic RNA-seq quantification. Nat. Biotechnol. 34, 525–527 (2016).
pubmed: 27043002
doi: 10.1038/nbt.3519
Love, M. I., Huber, W. & Anders, S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 15, 550 (2014).
pubmed: 25516281
pmcid: 4302049
doi: 10.1186/s13059-014-0550-8