The cardiovascular challenges in giraffes.
Cardiac output
Cerebral perfusion
Edema
Renal function
Vascular structure
Journal
Journal of muscle research and cell motility
ISSN: 1573-2657
Titre abrégé: J Muscle Res Cell Motil
Pays: Netherlands
ID NLM: 8006298
Informations de publication
Date de publication:
Jun 2023
Jun 2023
Historique:
received:
10
05
2022
accepted:
10
07
2022
medline:
10
7
2023
pubmed:
26
7
2022
entrez:
25
7
2022
Statut:
ppublish
Résumé
Giraffes are the highest living animals on Earth and therefore are challenged by gravity more than any other species. In particular the cardiovascular system needs to adapt to this challenge. Giraffes have a mean blood pressure around 200 mmHg, which ensures a mean arterial pressure near the head of 100 mmHg when the giraffe is standing with the neck in a near vertical position. This immediately raises several questions. How do giraffes avoid edema in the legs where the arterial pressure is 300 mmHg or higher? How does the heart produce a pressure of 200 mmHg, and what is the energy required for this endeavor? How can the kidney tolerate a pressure of about 200 mmHg and does this mean that giraffes have a high glomerular filtration rate? What is the arterial pressure in the head of giraffes when they drink, and how is perfusion of the brain maintained when they lift their head after drinking? In this short review, we present some answers to these questions.
Identifiants
pubmed: 35879488
doi: 10.1007/s10974-022-09626-0
pii: 10.1007/s10974-022-09626-0
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
53-60Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer Nature Switzerland AG.
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