Pulmonary Artery Enlargement: An Independent Risk Factor for Mortality in Patients Hospitalized With COVID-19.

COVID-19, coronavirus disease NCCT, noncontrast nongated computed tomography NEWS2, National Early Warning Score 2 PAD, pulmonary artery diameter PCFS, Post–COVID-19 Functional Status SARS-Cov-2, severe acute respiratory syndrome coronavirus 2

Journal

Mayo Clinic proceedings. Innovations, quality & outcomes
ISSN: 2542-4548
Titre abrégé: Mayo Clin Proc Innov Qual Outcomes
Pays: Netherlands
ID NLM: 101728275

Informations de publication

Date de publication:
Oct 2022
Historique:
pubmed: 27 7 2022
medline: 27 7 2022
entrez: 26 7 2022
Statut: ppublish

Résumé

To assess whether baseline pulmonary artery diameter (PAD), obtained from noncontrast nongated computed tomography (NCCT), can be associated with coronavirus disease 2019 (COVID-19) outcomes. This is a retrospective study of patients hospitalized with COVID-19 admitted to Hôtel-Dieu de France university hospital (Beirut, Lebanon) between March 1, 2020 and March 1, 2021. Pulmonary artery diameter was measured at baseline NCCT. Various outcomes were assessed, including hospital length of stay, intensive care unit admission, invasive mechanical ventilation, mortality, and Post-COVID-19 Functional Status scale at discharge and at 2-month follow-up. Four hundred sixty-five patients underwent baseline NCCT, including 315 men (67.7%) with a mean age of 63.7±16 years. Baseline PAD was higher in critically ill patients admitted to the intensive care unit (mean difference, 0.8 mm; 95% CI, 0.4-1.59 mm) and those receiving invasive mechanical ventilation (mean difference, 1.1 mm; 95% CI, 0.11-2.04 mm). Pulmonary artery diameter at baseline correlated significantly with hospital length of stay ( Baseline PAD measurement using NCCT can be a useful prognostic parameter. Its measurement can help to identify early severe cases and adapt the initial management of patients hospitalized with COVID-19.

Identifiants

pubmed: 35880237
doi: 10.1016/j.mayocpiqo.2022.07.001
pii: S2542-4548(22)00046-7
pmc: PMC9300717
doi:

Types de publication

Journal Article

Langues

eng

Pagination

399-408

Informations de copyright

© 2022 Published by Elsevier Inc on behalf of Mayo Foundation for Medical Education and Research.

Références

PLoS One. 2020 Feb 20;15(2):e0229173
pubmed: 32078644
Am J Physiol Lung Cell Mol Physiol. 2020 Aug 1;319(2):L277-L288
pubmed: 32551862
N Engl J Med. 2012 Sep 6;367(10):913-21
pubmed: 22938715
Eur Respir J. 2020 Jul 2;56(1):
pubmed: 32398306
Radiographics. 2018 May-Jun;38(3):719-739
pubmed: 29757717
PLoS One. 2020 Nov 17;15(11):e0241955
pubmed: 33201896
Heart. 2011 Apr;97(8):612-22
pubmed: 21357375
JAMA Intern Med. 2020 Oct 1;180(10):1345-1355
pubmed: 32667669
Respirology. 2019 Aug;24(8):777-782
pubmed: 30866125
Eur Radiol. 2021 Jun;31(6):4031-4041
pubmed: 33355697
N Engl J Med. 2020 Feb 20;382(8):727-733
pubmed: 31978945
Clin Chem Lab Med. 2020 Jun 25;58(7):1131-1134
pubmed: 32119647
Herz. 2021 Feb;46(1):56-62
pubmed: 33433652
Respir Care. 2020 Jan;65(1):111-126
pubmed: 31615921
Int J Chron Obstruct Pulmon Dis. 2017 May 12;12:1439-1446
pubmed: 28553096
JAMA. 2020 May 26;323(20):2052-2059
pubmed: 32320003
Lancet. 2020 Mar 28;395(10229):1054-1062
pubmed: 32171076
Eur Respir J. 2019 Jan 24;53(1):
pubmed: 30545968
Eur Radiol. 2020 Oct;30(10):5720-5727
pubmed: 32415585
Am J Hematol. 2020 Jul;95(7):834-847
pubmed: 32282949
Emerg Microbes Infect. 2020 Dec;9(1):1123-1130
pubmed: 32475230
Annu Rev Pathol. 2011;6:147-63
pubmed: 20936936
Diabetes Care. 2022 Mar 1;45(3):692-700
pubmed: 35045184
Am J Cardiol. 2022 Apr 1;168:176-178
pubmed: 35090698
Vascul Pharmacol. 2021 Apr;137:106829
pubmed: 33422689
Nat Immunol. 2022 Feb;23(2):194-202
pubmed: 35105985
Thromb Res. 2020 Nov;195:219-225
pubmed: 32777639
Clin Med (Lond). 2019 May;19(3):260
pubmed: 31092526
BMJ. 2020 Apr 7;369:m1328
pubmed: 32265220
Scand J Trauma Resusc Emerg Med. 2020 Jul 13;28(1):66
pubmed: 32660623
Nat Commun. 2020 Dec 9;11(1):6317
pubmed: 33298944
Microbiol Mol Biol Rev. 2012 Mar;76(1):16-32
pubmed: 22390970
Int J Infect Dis. 2020 Jun;95:304-307
pubmed: 32344011
Crit Care Resusc. 2020 Apr 15;22(2):95-97
pubmed: 32294809
Allergy. 2021 Feb;76(2):428-455
pubmed: 33185910
JACC Cardiovasc Imaging. 2020 Nov;13(11):2287-2299
pubmed: 32654963
Cancer Biol Med. 2020 Aug 15;17(3):519-527
pubmed: 32944387
Nat Immunol. 2022 Feb;23(2):210-216
pubmed: 35027728
Jpn J Radiol. 2021 Jun;39(6):589-597
pubmed: 33751417

Auteurs

Moussa A Riachy (MA)

Division of Pulmonary and critical care medicine, Hôtel Dieu de France Hospital, Beirut, Lebanon.

Anis Ismail (A)

Faculty of Medicine, Saint Joseph University of Beirut, Lebanon.

Mohamad Awali (M)

Division of Radiology, Faculty of Medicine, Hôtel Dieu de France Hospital, Beirut, Lebanon.

Fadi Farah (F)

Division of Radiology, Faculty of Medicine, Hôtel Dieu de France Hospital, Beirut, Lebanon.

Sara F Haddad (SF)

Faculty of Medicine, Saint Joseph University of Beirut, Lebanon.

Anthony Kerbage (A)

Faculty of Medicine, Saint Joseph University of Beirut, Lebanon.

Noel Aoun (N)

Division of Radiology, Faculty of Medicine, Hôtel Dieu de France Hospital, Beirut, Lebanon.

Ghassan Sleilaty (G)

Division of Cardiovascular Surgery, Hôtel Dieu de France Hospital, Beirut, Lebanon.

Classifications MeSH