Anorectal malformation, urethral duplication, occult spinal dysraphism (ARM-UD-OSD): a challenging uncommon association.

Anorectal Malformations / complications Child Humans Male Neural Tube Defects / complications Retrospective Studies Urinary Bladder, Neurogenic
Anorectal malformation Neurogenic bladder Occult spinal dysraphism Urethral duplication

Journal

Pediatric surgery international
ISSN: 1437-9813
Titre abrégé: Pediatr Surg Int
Pays: Germany
ID NLM: 8609169

Informations de publication

Date de publication:
Oct 2022
Historique:
accepted: 14 07 2022
pubmed: 27 7 2022
medline: 14 9 2022
entrez: 26 7 2022
Statut: ppublish

Résumé

Urethral duplication (UD) is a rare malformation, which can be associated with other anomalies, like anorectal malformations (ARM). ARM has been described with occult spinal dysraphism (OSD). No ARM-UD-OSD combination has been reported. To share our experience and to discuss the management of ARM-UD-OSD association. We retrospectively reviewed records of five boys with UD. Four of these had ARM-UD-OSD association. ARM was the first diagnosis in all; OSD and UD was detected during screening for associated malformation. All patients underwent ARM correction, 3 after colostomy. All reached fecal continence, 3 are performing bowel management. Three patients underwent UD surgical correction. Because of symptoms' worsening, 2 children had detethering surgery. At a mean follow-up of 9.5 years, all patients have normal renal function, 3 are on clean intermittent catheterization (CIC) for neurogenic bladder (1 has a cystostomy, another one an appendicostomy). UD and OSD should be considered in patients with ARM. Children with these conditions associated must be centralized in a third-level Center and management carefully planned; in particular, urethral reconstruction should be weighed, considering CIC could be required. Suspicion of neurogenic bladder must be present in OSD patient.

Identifiants

DOI: 10.1007/s00383-022-05186-z PMID: 35882671
pubmed: 35882671
doi: 10.1007/s00383-022-05186-z
pii: 10.1007/s00383-022-05186-z
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1487-1494

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Références

Salle JL, Sibai H, Rosenstein D, Brzezinski AE, Corcos J (2000) Urethral duplication in the male: review of 16 cases. J Urol 163(6):1936–1940
doi: 10.1016/S0022-5347(05)67602-1
Onofre LS, Gomes AL, Leão JQ, Leão FG, Cruz TM, Carnevale J (2013) Urethral duplication—A wide spectrum of anomalies. J Pediatr Urol. 9(6):1064–71. https://doi.org/10.1016/j.jpurol.2013.03.006
doi: 10.1016/j.jpurol.2013.03.006 pubmed: 23623406
Das S, Brosman SA (1977) Duplication of the male urethra. J Urol 117(4):452–454. https://doi.org/10.1016/s0022-5347(17)58496-7
doi: 10.1016/s0022-5347(17)58496-7 pubmed: 850318
Ortolano V, Nasrallah PF (1986) Urethral duplication. J Urol 136(4):909–912. https://doi.org/10.1016/s0022-5347(17)45125-1
doi: 10.1016/s0022-5347(17)45125-1 pubmed: 3761458
Effmann EL, Lebowitz RL, Colodny AH (1976) Duplication of the urethra. Radiology 119(1):179–185. https://doi.org/10.1148/119.1.179
doi: 10.1148/119.1.179 pubmed: 943804
Guglielmetti LC, Delcont M, Walker J, Wilcox D, Vuille-Dit-Bille RN (2020) Urethral duplication-Epidemiology, diagnosis, and treatment in a case series of 19 patients. J Pediatr Urol 16(3):385.e1-385.e9. https://doi.org/10.1016/j.jpurol.2020.02.010
doi: 10.1016/j.jpurol.2020.02.010
Caione P, Angotti R, Molinaro F, Pellegrino C, Scuglia M, Gerocarni Nappo S, Messina M (2020) Urethral duplication in male epispadias: a very uncommon association. Minerva Urol Nefrol 72(2):229–235. https://doi.org/10.23736/S0393-2249.19.03271-5
doi: 10.23736/S0393-2249.19.03271-5 pubmed: 30957471
Singal AK, Bhatnagar V, Agarwala S, Mitra DK (2006) Urethral duplication in association with anorectal malformation. Eur J Pediatr Surg 16(3):214–216. https://doi.org/10.1055/s-2006-924204
doi: 10.1055/s-2006-924204 pubmed: 16909364
Nerli RB, Ghagane SC, Dixit NS, Hiremath MB (2018) Urethral duplication in a child with VATER association. Urol Case Rep 23:29–31. https://doi.org/10.1016/j.eucr.2018.11.018
doi: 10.1016/j.eucr.2018.11.018 pubmed: 30534525 pmcid: 6282190
Kang SK, Kim J, Lee YS, Han SW, Kim S (2020) Urethral duplication in male children: a study of 12 cases. J Pediatr Surg 55(10):2216–2220. https://doi.org/10.1016/j.jpedsurg.2019.12.012
doi: 10.1016/j.jpedsurg.2019.12.012 pubmed: 32063365
Haleblian G, Kraklau D, Wilcox D, Duffy P, Ransley P, Mushtaq I (2006) Y-type urethral duplication in the male. BJU Int 97(3):597–602. https://doi.org/10.1111/j.1464-410X.2006.06025.x
doi: 10.1111/j.1464-410X.2006.06025.x pubmed: 16469034
Totonelli G, Messina R, Morini F, Mosiello G, Palma P, Scuglia M, Iacobelli BD, Bagolan P (2017) Embryological and clinical implications of the association between anorectal malformations and spinal dysraphisms. Pediatr Surg Int 33(8):843–847. https://doi.org/10.1007/s00383-017-4104-5
doi: 10.1007/s00383-017-4104-5 pubmed: 28601900
Van den Hondel D, Sloots C, de Jong TH, Lequin M, Wijnen R (2016) Screening and treatment of tethered spinal cord in anorectal malformation patients. Eur J Pediatr Surg 26(1):22–28. https://doi.org/10.1055/s-0035-1563673
doi: 10.1055/s-0035-1563673 pubmed: 26394371
Freitas Filho LG, Martins CS, Carnevale J, Kanasiro F, Budib LJ (2018) Spinal lipoma associated with urethral duplication. Urol Case Rep 19:11–12. https://doi.org/10.1016/j.eucr.2018.04.002
doi: 10.1016/j.eucr.2018.04.002 pubmed: 29888176 pmcid: 5991332
Mosiello G, Capitanucci ML, Gatti C, Adorisio O, Lucchetti MC, Silveri M, Schingo PS, De Gennaro M (2003) How to investigate neurovesical dysfunction in children with anorectal malformations. J Urol 170(4 Pt 2):1610–1613. https://doi.org/10.1097/01.ju.0000083883.16836.91
doi: 10.1097/01.ju.0000083883.16836.91 pubmed: 14501674
Kearns JT, Esposito D, Dooley B, Frim D, Gundeti MS (2013) Urodynamic studies in spinal cord tethering. Childs Nerv Syst 29(9):1589–1600. https://doi.org/10.1007/s00381-013-2136-2
doi: 10.1007/s00381-013-2136-2 pubmed: 24013329
Park K (2020) Urological evaluation of tethered cord syndrome. J Korean Neurosurg Soc 63(3):358–365. https://doi.org/10.3340/jkns.2020.0072
doi: 10.3340/jkns.2020.0072 pubmed: 32392667 pmcid: 7218197
Stein R, Bogaert G, Dogan HS et al (2020) EAU/ESPU guidelines on the management of neurogenic bladder in children and adolescent part I diagnostics and conservative treatment. Neurourol Urodyn 39:45–57. https://doi.org/10.1002/nau.24211
doi: 10.1002/nau.24211 pubmed: 31724222
Pascali MP, Mosiello G, Marciano A, Capitanucci ML, Zaccara AM, De Gennaro M (2011) A simplified technique for botulinum toxin injections in children with neurogenic bladder. J Urol 185(6 Suppl):2558–2562. https://doi.org/10.1016/j.juro.2011.01.037
doi: 10.1016/j.juro.2011.01.037 pubmed: 21527204
Stein R, Bogaert G, Dogan HS et al (2020) EAU/ESPU guidelines on the management of neurogenic bladder in children and adolescent part II operative management. Neurourol Urodyn 39:498–506. https://doi.org/10.1002/nau.24248
doi: 10.1002/nau.24248 pubmed: 31794087
Mosiello G, Lopes Mendes AL, Capitanucci ML, Zaccara AM, De Gennaro M (2017) Button cystostomy: is it really a safe and effective therapeutic option in pediatric patients with neurogenic bladder? Urology 101:73–79. https://doi.org/10.1016/j.urology.2016.09.025
doi: 10.1016/j.urology.2016.09.025 pubmed: 27693876
Bradshaw CJ, Gray R, Downer A, Hitchcock R (2014) Button vesicostomy: 13 years of experience. J Pediatr Urol 10(1):80–87. https://doi.org/10.1016/j.jpurol.2013.06.008
doi: 10.1016/j.jpurol.2013.06.008 pubmed: 23900025
Woodhouse CR, Williams DI (1979) Duplications of the lower urinary tract in children. Br J Urol 51(6):481–487. https://doi.org/10.1111/j.1464-410x.1979.tb03583.x
doi: 10.1111/j.1464-410x.1979.tb03583.x pubmed: 534829
Golonka NR, Haga LJ, Keating RP, Eichelberger MR, Gilbert JC, Hartman GE et al (2002) Routine MRI evaluation of low imperforate anus reveals unexpected high incidence of tethered spinal cord. J Pediatr Surg 37(7):966–9. https://doi.org/10.1053/jpsu.2002.33817
doi: 10.1053/jpsu.2002.33817 pubmed: 12077750
Ailawadhi P, Kale SS, Agrawal D, Mahapatra AK, Kumar R (2012) Primary tethered cord syndrome–clinical and urological manifestations, diagnosis and management: a prospective study. Pediatr Neurosurg 48(4):210–215. https://doi.org/10.1159/000345829
doi: 10.1159/000345829 pubmed: 23713055
Teo AT, Gan BK, Tung JS, Low Y, Seow WT (2012) Low-lying spinal cord and tethered cord syndrome in children with anorectal malformations. Singapore Med J 53(9):570–576
pubmed: 23023896
Tuuha SE, Aziz D, Drake J, Wales P, Kim PC (2004) Is surgery necessary for asymptomatic tethered cord in anorectal malformation patients? J Pediatr Surg 39(5):773–777. https://doi.org/10.1016/j.jpedsurg.2004.01.023
doi: 10.1016/j.jpedsurg.2004.01.023 pubmed: 15137017
Suppiej A, Dal Zotto L, Cappellari A, Traverso A, Castagnetti M, Drigo P, Midrio P (2009) Tethered cord in patients with anorectal malformation: preliminary results. Pediatr Surg Int 25(10):851–855. https://doi.org/10.1007/s00383-009-2435-6
doi: 10.1007/s00383-009-2435-6 pubmed: 19680666
Capitanucci ML, Iacobelli BD, Silveri M, Mosiello G, De Gennaro M (1996) Long-term urological follow-up of occult spinal dysraphism in children. Eur J Pediatr Surg 6(suppl 1):25–26. https://doi.org/10.1055/s-2008-1071033
doi: 10.1055/s-2008-1071033 pubmed: 9008815
Inoue M, Uchida K, Otake K, Nagano Y, Shimura T, Hashimoto K et al (2017) Long-term functional outcome after untethering surgery for a tethered spinal cord in patients with anorectal malformations. Pediatr Surg Int 33(9):995–999. https://doi.org/10.1007/s00383-017-4127-y
doi: 10.1007/s00383-017-4127-y pubmed: 28779274
Morimoto K, Takemoto O, Wakayama A (2003) Tethered cord associated with anorectal malformation. Pediatr Neurosurg 38(2):79–82. https://doi.org/10.1159/000068048
doi: 10.1159/000068048 pubmed: 12566840
Podesta ML, Medel R, Castera R, Ruarte AC (1998) Urethral duplication in children: surgical treatment and results. J Urol 160(5):1830–1833. https://doi.org/10.1016/s0022-5347(01)62427-3
doi: 10.1016/s0022-5347(01)62427-3 pubmed: 9783969
Fernbach SK (1991) Urethral abnormalities in male neonates with VATER association. AJR Am J Roentgenol 156(1):137–140. https://doi.org/10.2214/ajr.156.1.1898547
doi: 10.2214/ajr.156.1.1898547 pubmed: 1898547
Lima M, Destro F, Di Salvo N, Gargano T, Ruggeri G (2017) Fate of males with urethral “Y-duplication”: 40-year long follow-up in 8 patients. J Pediatr Surg 52(8):1335–1339. https://doi.org/10.1016/j.jpedsurg.2016.11.034
doi: 10.1016/j.jpedsurg.2016.11.034 pubmed: 27912972
Lorenz C, Zahn K, Schäfer FM, Möller K, Stehr M, Stein R (2021) Congenital Y-urethra—A diagnostic and therapeutic challenge. J Pediatr Urol 17(1):30–38. https://doi.org/10.1016/j.jpurol.2020.11.032
doi: 10.1016/j.jpurol.2020.11.032 pubmed: 33317944
Stamates MM, Frim DM, Yang CW, Katzman GL, Ali S (2018) Magnetic resonance imaging in the prone position and the diagnosis of tethered spinal cord. J Neurosurg Pediatr 21(1):4–10. https://doi.org/10.3171/2017.3.PEDS16596
doi: 10.3171/2017.3.PEDS16596 pubmed: 29076793

Auteurs

Federica Lena (F)

Division of Neuro-Urology, Bambino Gesu' Children's Hospital, IRCCS, Piazza di Sant'Onofrio 4, 00165, Rome, Italy.
University of Genoa, DINOGMI, Largo Paolo Daneo 3, 16132, Genoa, Italy.

Chiara Pellegrino (C)

Division of Neuro-Urology, Bambino Gesu' Children's Hospital, IRCCS, Piazza di Sant'Onofrio 4, 00165, Rome, Italy. chiara.pellegrino@opbg.net.

Antonio Maria Zaccara (AM)

Division of Neuro-Urology, Bambino Gesu' Children's Hospital, IRCCS, Piazza di Sant'Onofrio 4, 00165, Rome, Italy.

Maria Luisa Capitanucci (ML)

Division of Neuro-Urology, Bambino Gesu' Children's Hospital, IRCCS, Piazza di Sant'Onofrio 4, 00165, Rome, Italy.

Giacomo Esposito (G)

Department of Neuroscience, Neurosurgery Unit, Bambino Gesu' Children's Hospital, IRCCS, Piazza di Sant'Onofrio 4, 00165, Rome, Italy.

Barbara Daniela Iacobelli (BD)

Medical and Surgical Department of the Fetus-Newborn-Infant, Newborn Surgery Unit, Bambino Gesu' Children's Hospital IRCCS, Piazza di Sant'Onofrio 4, 00165, Rome, Italy.

Daniela Longo (D)

Imaging Department, Neuroradiology Unit, Bambino Gesu' Children's Hospital, IRCCS, Piazza di Sant'Onofrio 4, 00165, Rome, Italy.

Tamara Caldaro (T)

Division of Digestive Surgery and Endoscopy, Bambino Gesu' Children's Hospital, IRCCS, Piazza di Sant'Onofrio 4, 00165, Rome, Italy.

Diletta Bruno (D)

Department of Neurorehabilitation, Bambino Gesu' Children's Hospital, IRCCS, Piazza di Sant'Onofrio 4, 00165, Rome, Italy.

Francesca Bevilacqua (F)

Department of Neuroscience, Unit of Clinical Psychology, Bambino Gesu' Children's Hospital, IRCCS, Piazza di Sant'Onofrio 4, 00165, Rome, Italy.

Francesca Santato (F)

Department of Neuroscience, Unit of Clinical Psychology, Bambino Gesu' Children's Hospital, IRCCS, Piazza di Sant'Onofrio 4, 00165, Rome, Italy.

Giulia Lucignani (G)

Imaging Department, Neuroradiology Unit, Bambino Gesu' Children's Hospital, IRCCS, Piazza di Sant'Onofrio 4, 00165, Rome, Italy.

Carlo Efisio Marras (CE)

Department of Neuroscience, Neurosurgery Unit, Bambino Gesu' Children's Hospital, IRCCS, Piazza di Sant'Onofrio 4, 00165, Rome, Italy.

Enrico Castelli (E)

Department of Neurorehabilitation, Bambino Gesu' Children's Hospital, IRCCS, Piazza di Sant'Onofrio 4, 00165, Rome, Italy.

Pietro Bagolan (P)

Medical and Surgical Department of the Fetus-Newborn-Infant, Newborn Surgery Unit, Bambino Gesu' Children's Hospital IRCCS, Piazza di Sant'Onofrio 4, 00165, Rome, Italy.
Department of Systems Medicine, University of Rome "Tor Vergata", Piazza di Sant'Onofrio 4, 00165, Rome, Italy.

Giovanni Mosiello (G)

Division of Neuro-Urology, Bambino Gesu' Children's Hospital, IRCCS, Piazza di Sant'Onofrio 4, 00165, Rome, Italy.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Malformations et maladies congénitales, héréditaires et néonatales › Malformations › Malformations de l'appareil digestif › Malformations anorectales › Anorectal malformation, urethral duplication,...
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Anorectal malformation, urethral duplication,...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Anorectal malformation, urethral duplication,...
questionsmedicales.fr › Malformations et maladies congénitales, héréditaires et néonatales › Malformations › Malformations du système nerveux › Anomalies du tube neural › Anorectal malformation, urethral duplication,...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études rétrospectives › Anorectal malformation, urethral duplication,...
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Manifestations neurologiques › Vessie neurologique › Anorectal malformation, urethral duplication,...