Clinical Efficacy of Empirical Therapy in Children with Vasovagal Syncope.
children
efficacy
empiric therapy
vasovagal syncope
Journal
Children (Basel, Switzerland)
ISSN: 2227-9067
Titre abrégé: Children (Basel)
Pays: Switzerland
ID NLM: 101648936
Informations de publication
Date de publication:
17 Jul 2022
17 Jul 2022
Historique:
received:
01
07
2022
revised:
14
07
2022
accepted:
15
07
2022
entrez:
27
7
2022
pubmed:
28
7
2022
medline:
28
7
2022
Statut:
epublish
Résumé
(1) Background: This case-control study was designed to assess the efficacy of empiric treatment for vasovagal syncope in children; (2) Methods: We retrospectively enrolled 181 children with vasovagal syncope from the Department of Pediatrics of Peking University First Hospital. The participants were categorized into four groups, based on the empiric treatment received: conventional treatment, including health education and orthostatic training; conventional treatment plus oral rehydration salts; conventional treatment plus metoprolol; conventional treatment plus midodrine hydrochloride. Patients were followed up to evaluate the syncopal or presyncopal recurrence. Kaplan-Meier curves were drawn to explore the syncopal or presyncopal recurrence in children, and the differences were compared among the groups using a log-rank test; (3) Results: Among the 181 children with vasovagal syncope, 11 were lost to follow-up. The median time of follow-up was 20 (8, 42) months. The Kaplan-Meier survival curve showed no significant difference in syncopal or presyncopal recurrence in children treated with different empiric options according to a log-rank test (
Identifiants
pubmed: 35884049
pii: children9071065
doi: 10.3390/children9071065
pmc: PMC9315970
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Fundamental Research Funds for the Central Universities, and Guangzhou Women and Children's Medical Center Internal Program
ID : 2020BS012
Organisme : National High Level Hospital Clinical Research Funding (Multi-center Clinical Research Project of Peking University First Hospital)
ID : 2022CR59
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