Modulating the Fibrillization of Parathyroid-Hormone (PTH) Peptides: Azo-Switches as Reversible and Catalytic Entities.

aggregation azobenzene fibrillization parathyroid hormone photoswitchable peptides

Journal

Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304

Informations de publication

Date de publication:
26 Jun 2022
Historique:
received: 23 05 2022
revised: 20 06 2022
accepted: 23 06 2022
entrez: 27 7 2022
pubmed: 28 7 2022
medline: 28 7 2022
Statut: epublish

Résumé

We here report a novel strategy to control the bioavailability of the fibrillizing parathyroid hormone (PTH)-derived peptides, where the concentration of the bioactive form is controlled by an reversible, photoswitchable peptide. PTH

Identifiants

pubmed: 35884817
pii: biomedicines10071512
doi: 10.3390/biomedicines10071512
pmc: PMC9313110
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Deutsche Forschungsgemeinschaft
ID : Project ID 189853844 - TRR 102, TP A12

Références

Chemphyschem. 2019 Jan 21;20(2):236-240
pubmed: 30221816
J Am Chem Soc. 2005 Mar 9;127(9):2929-36
pubmed: 15740129
Science. 2009 Jul 17;325(5938):328-32
pubmed: 19541956
J Biol Chem. 2003 Sep 26;278(39):37530-5
pubmed: 12815044
Phys Chem Chem Phys. 2019 Oct 7;21(37):20999-21006
pubmed: 31528872
Bioconjug Chem. 2004 Nov-Dec;15(6):1297-303
pubmed: 15546196
Eur J Biochem. 2002 Aug;269(16):4159-63
pubmed: 12180993
Recent Prog Horm Res. 1983;39:181-209
pubmed: 6356251
Endocr Rev. 2021 Jul 16;42(4):383-406
pubmed: 33564837
Angew Chem Int Ed Engl. 2011 Aug 8;50(33):7699-702
pubmed: 21739542
Science. 2021 Nov 12;374(6569):848-856
pubmed: 34762454
Chemistry. 2019 Apr 1;25(19):4965-4973
pubmed: 30735272
Photochem Photobiol. 2020 Nov;96(6):1163-1168
pubmed: 32521572
Biochim Biophys Acta. 2015 Apr;1854(4):249-57
pubmed: 25554227
Angew Chem Int Ed Engl. 2012 Jun 25;51(26):6452-5
pubmed: 22644657
IUBMB Life. 2007 Apr-May;59(4-5):332-45
pubmed: 17505973
Angew Chem Int Ed Engl. 2015 Dec 14;54(51):15565-9
pubmed: 26585495
Bioorg Chem. 2020 Aug;101:104012
pubmed: 32683138
Chembiochem. 2019 Jun 3;20(11):1417-1429
pubmed: 30675988
J Mater Chem B. 2019 Dec 14;7(46):7267-7282
pubmed: 31647489
Adv Nephrol Necker Hosp. 1994;23:265-79
pubmed: 8154358
Macromol Rapid Commun. 2020 Jan;41(1):e1900378
pubmed: 31631446
J Biol Chem. 2012 Jan 27;287(5):3479-84
pubmed: 22147705
Nat Struct Mol Biol. 2010 May;17(5):561-7
pubmed: 20383142
Mol Med. 2008 Jul-Aug;14(7-8):451-64
pubmed: 18368143
Angew Chem Int Ed Engl. 2006 Nov 13;45(44):7324-8
pubmed: 17054297
Am J Physiol Regul Integr Comp Physiol. 2007 Feb;292(2):R679-96
pubmed: 17023665
PLoS Biol. 2006 Jan;4(1):e6
pubmed: 16300414
Angew Chem Int Ed Engl. 2007;46(43):8128-47
pubmed: 17935097
Angew Chem Int Ed Engl. 2010 May 25;49(23):3943-6
pubmed: 20419720
J Mol Biol. 1997 Oct 31;273(3):729-39
pubmed: 9356260
Structure. 2001 Feb 7;9(2):83-91
pubmed: 11250193
Prog Nucl Magn Reson Spectrosc. 2015 Aug;88-89:86-104
pubmed: 26282197
Gut. 1972 Jul;13(7):579-85
pubmed: 4403576
Science. 2002 Feb 1;295(5556):851-5
pubmed: 11823641
Org Biomol Chem. 2004 Oct 7;2(19):2798-801
pubmed: 15455152
Mol Endocrinol. 1987 Sep;1(9):628-38
pubmed: 3153480
Chem Soc Rev. 2012 Mar 7;41(5):1809-25
pubmed: 22008710
Chem Rev. 2018 Nov 14;118(21):10710-10747
pubmed: 29985590
Cell. 2012 Jul 20;150(2):339-50
pubmed: 22817896
Methods Enzymol. 1999;309:274-84
pubmed: 10507030
Chemistry. 2009;15(2):501-5
pubmed: 19065552
J Biol Chem. 1988 Dec 25;263(36):19771-7
pubmed: 3198649
Trends Pharmacol Sci. 2000 Apr;21(4):128-30
pubmed: 10740285
Endocr Rev. 2008 May;29(3):303-16
pubmed: 18314421
Nat Chem Biol. 2009 Oct;5(10):724-6
pubmed: 19734911
J Mol Biol. 2004 Jan 30;335(5):1279-88
pubmed: 14729343
Chembiochem. 2018 Dec 18;19(24):2591-2597
pubmed: 30324702
Polymers (Basel). 2016 May 02;8(5):
pubmed: 30979271
Endocrinology. 1991 Jul;129(1):421-8
pubmed: 2055197
Nat Chem Biol. 2006 Jan;2(1):47-52
pubmed: 16408092

Auteurs

André Paschold (A)

Department of Chemistry, Faculty of Natural Sciences II, Martin-Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany.

Bruno Voigt (B)

Department of Physics, Faculty of Natural Sciences II, Martin-Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany.

Gerd Hause (G)

Biozentrum, Martin-Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany.

Tim Kohlmann (T)

Department of Chemistry, Faculty of Natural Sciences II, Martin-Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany.

Sven Rothemund (S)

Core Unit Peptide-Technologies, University Leipzig, 04103 Leipzig, Germany.

Wolfgang H Binder (WH)

Department of Chemistry, Faculty of Natural Sciences II, Martin-Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany.

Classifications MeSH