Protein Intake and Sarcopenia in Older Adults: A Systematic Review and Meta-Analysis.
anorexia
dynapenia
elderly
frailty
muscle strength
nutrition
physical function
walking speed
Journal
International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455
Informations de publication
Date de publication:
18 07 2022
18 07 2022
Historique:
received:
02
06
2022
revised:
02
07
2022
accepted:
09
07
2022
entrez:
27
7
2022
pubmed:
28
7
2022
medline:
29
7
2022
Statut:
epublish
Résumé
The present systematic review and meta-analysis investigated the cross-sectional and longitudinal associations between protein intake and sarcopenia in older adults. Observational studies that investigated the association between protein intake and sarcopenia as the primary or secondary outcome in people aged 60 years and older were included. Studies published in languages other than English, Italian, Portuguese, and Spanish were excluded. Studies were retrieved from MEDLINE, SCOPUS, EMBASE, CINAHL, AgeLine, and Food Science Source databases through January 31, 2022. A pooled effect size was calculated based on standard mean differences. Five cross-sectional studies, one longitudinal study, and one case-control study that investigated 3353 community-dwelling older adults with a mean age of approximately 73 years were included. The meta-analysis of four studies indicated that older adults with sarcopenia consumed significantly less protein than their peers with no sarcopenia. Results of the present study suggest that an inadequate protein intake might be associated with sarcopenia in older adults.
Sections du résumé
BACKGROUND
The present systematic review and meta-analysis investigated the cross-sectional and longitudinal associations between protein intake and sarcopenia in older adults.
METHODS
Observational studies that investigated the association between protein intake and sarcopenia as the primary or secondary outcome in people aged 60 years and older were included. Studies published in languages other than English, Italian, Portuguese, and Spanish were excluded. Studies were retrieved from MEDLINE, SCOPUS, EMBASE, CINAHL, AgeLine, and Food Science Source databases through January 31, 2022. A pooled effect size was calculated based on standard mean differences.
RESULTS
Five cross-sectional studies, one longitudinal study, and one case-control study that investigated 3353 community-dwelling older adults with a mean age of approximately 73 years were included. The meta-analysis of four studies indicated that older adults with sarcopenia consumed significantly less protein than their peers with no sarcopenia.
CONCLUSIONS
Results of the present study suggest that an inadequate protein intake might be associated with sarcopenia in older adults.
Identifiants
pubmed: 35886571
pii: ijerph19148718
doi: 10.3390/ijerph19148718
pmc: PMC9320473
pii:
doi:
Types de publication
Journal Article
Meta-Analysis
Review
Systematic Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Références
J Nutr Health Aging. 2021;25(7):824-853
pubmed: 34409961
J Cachexia Sarcopenia Muscle. 2019 Oct;10(5):956-961
pubmed: 31523937
Age Ageing. 2010 Jul;39(4):412-23
pubmed: 20392703
J Appl Physiol (1985). 2009 Sep;107(3):987-92
pubmed: 19589961
Nutrients. 2020 Nov 24;12(12):
pubmed: 33255223
FASEB J. 2005 Mar;19(3):422-4
pubmed: 15596483
Nutrients. 2018 Sep 19;10(9):
pubmed: 30235893
Nutrition. 2008 Jun;24(6):546-53
pubmed: 18455655
Br J Nutr. 2019 Feb;121(4):393-401
pubmed: 30419973
Nutrients. 2020 Jun 01;12(6):
pubmed: 32492947
Am J Clin Nutr. 2010 Nov;92(5):1080-8
pubmed: 20844073
J Am Med Dir Assoc. 2020 Mar;21(3):300-307.e2
pubmed: 32033882
Curr Opin Clin Nutr Metab Care. 2014 Jan;17(1):25-31
pubmed: 24310054
J Nutr. 2000 Nov;130(11):2630-5
pubmed: 11053498
Res Synth Methods. 2020 Sep;11(5):641-654
pubmed: 32562361
J Neurol Sci. 1988 Apr;84(2-3):275-94
pubmed: 3379447
J Nutr. 2004 Jul;134(7):1704-10
pubmed: 15226457
Exp Gerontol. 2013 May;48(5):492-8
pubmed: 23425621
Stat Methods Med Res. 2018 Jun;27(6):1785-1805
pubmed: 27683581
Clin Nutr. 2020 Dec;39(12):3839-3841
pubmed: 32376097
Ageing Res Rev. 2018 Nov;47:123-132
pubmed: 30048806
Clin Nutr. 2017 Feb;36(1):267-274
pubmed: 26689868
Am J Physiol Endocrinol Metab. 2008 Sep;295(3):E595-604
pubmed: 18577697
Aging Clin Exp Res. 2021 Aug;33(8):2069-2086
pubmed: 33587271
J Am Med Dir Assoc. 2014 Feb;15(2):95-101
pubmed: 24461239
J Physiol. 2003 Oct 1;552(Pt 1):315-24
pubmed: 12909668
J Nutr. 2007 Feb;137(2):357-62
pubmed: 17237311
J Nutr. 2015 Sep;145(9):1981-91
pubmed: 26224750
PLoS One. 2015 Nov 04;10(11):e0140903
pubmed: 26536130
Osteoporos Sarcopenia. 2021 Mar;7(Suppl 1):S19-S27
pubmed: 33997305
J Gerontol A Biol Sci Med Sci. 2014 May;69(5):584-90
pubmed: 24737561
Age Ageing. 2019 Jan 1;48(1):16-31
pubmed: 30312372
Aging Med (Milton). 2021 Dec 17;4(4):257-265
pubmed: 34964006
J Gerontol A Biol Sci Med Sci. 2015 Jan;70(1):57-62
pubmed: 25056502
Aging Clin Exp Res. 2019 Jun;31(6):815-824
pubmed: 30955158
Public Health Nutr. 2021 Oct;24(14):4490-4505
pubmed: 33023717
Am J Clin Nutr. 2005 Nov;82(5):1065-73
pubmed: 16280440
Nutrients. 2020 Sep 23;12(10):
pubmed: 32977714
J Am Med Dir Assoc. 2013 Aug;14(8):542-59
pubmed: 23867520
Aging Clin Exp Res. 2019 Jun;31(6):837-844
pubmed: 31115875
J Clin Endocrinol Metab. 2000 Dec;85(12):4481-90
pubmed: 11134097
Crit Rev Food Sci Nutr. 2017 Nov 22;57(17):3640-3649
pubmed: 26853923
Nutrients. 2016 May 14;8(5):
pubmed: 27187465
JAMA. 2000 Apr 19;283(15):2008-12
pubmed: 10789670
Nutrients. 2021 Nov 27;13(12):
pubmed: 34959843
Am J Physiol Endocrinol Metab. 2006 Aug;291(2):E381-7
pubmed: 16507602
Clin Nutr. 2020 Jan;39(1):166-173
pubmed: 30709690
J Int Soc Sports Nutr. 2015 Feb 05;12:6
pubmed: 25674042
J Frailty Aging. 2013;2(1):38-53
pubmed: 26082911
J Cachexia Sarcopenia Muscle. 2022 Jun;13(3):1653-1672
pubmed: 35307982
Curr Opin Clin Nutr Metab Care. 2015 May;18(3):248-53
pubmed: 25807346
J Physiol. 2013 Jun 1;591(11):2911-23
pubmed: 23551944
Int J Mol Sci. 2020 Jan 13;21(2):
pubmed: 31941015
J Cachexia Sarcopenia Muscle. 2022 Feb;13(1):86-99
pubmed: 34816624
Biomed Res Int. 2017;2017:2672435
pubmed: 28421192
Phys Ther. 2001 Nov;81(11):1810-6
pubmed: 11694174