AMD
CCL2 (rs1024611, rs4586, rs2857656)
CCL2 and CCR2 serum level
CCR2 rs1799865
Journal
Life (Basel, Switzerland)
ISSN: 2075-1729
Titre abrégé: Life (Basel)
Pays: Switzerland
ID NLM: 101580444
Informations de publication
Date de publication:
12 Jul 2022
12 Jul 2022
Historique:
received:
06
06
2022
revised:
01
07
2022
accepted:
08
07
2022
entrez:
27
7
2022
pubmed:
28
7
2022
medline:
28
7
2022
Statut:
epublish
Résumé
Age-related macular degeneration (AMD) is the most common cause of progressive and irreversible blindness in developed countries. Although the pathogenesis is not fully understood, AMD is a multifactorial pathology with an accumulation of inflammatory components and macrophages and a strong genetic predisposition. Our purpose was to investigate the association between early AMD and The study included 310 patients with early AMD and 384 healthy subjects. Genotyping of We found that the G allele at We found the associations between minor alleles at
Sections du résumé
BACKGROUND
BACKGROUND
Age-related macular degeneration (AMD) is the most common cause of progressive and irreversible blindness in developed countries. Although the pathogenesis is not fully understood, AMD is a multifactorial pathology with an accumulation of inflammatory components and macrophages and a strong genetic predisposition. Our purpose was to investigate the association between early AMD and
METHODS
METHODS
The study included 310 patients with early AMD and 384 healthy subjects. Genotyping of
RESULTS
RESULTS
We found that the G allele at
CONCLUSIONS
CONCLUSIONS
We found the associations between minor alleles at
Identifiants
pubmed: 35888126
pii: life12071038
doi: 10.3390/life12071038
pmc: PMC9322437
pii:
doi:
Types de publication
Journal Article
Langues
eng
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