The Role of Ferritin in Health and Disease: Recent Advances and Understandings.
COVID-19
ferritin
ferritinophagy
ferroptosis
iron disorders
Journal
Metabolites
ISSN: 2218-1989
Titre abrégé: Metabolites
Pays: Switzerland
ID NLM: 101578790
Informations de publication
Date de publication:
30 Jun 2022
30 Jun 2022
Historique:
received:
31
05
2022
revised:
25
06
2022
accepted:
27
06
2022
entrez:
27
7
2022
pubmed:
28
7
2022
medline:
28
7
2022
Statut:
epublish
Résumé
Systemic iron homeostasis needs to be tightly controlled, as both deficiency and excess iron cause major global health concerns, such as iron deficiency anemia, hemochromatosis, etc. In mammals, sufficient dietary acquisition is critical for fulfilling the systemic iron requirement. New questions are emerging about whether and how cellular iron transport pathways integrate with the iron storage mechanism. Ferritin is the intracellular iron storage protein that stores surplus iron after all the cellular needs are fulfilled and releases it in the face of an acute demand. Currently, there is a surge in interest in ferritin research after the discovery of novel pathways like ferritinophagy and ferroptosis. This review emphasizes the most recent ferritin-related discoveries and their impact on systemic iron regulation.
Identifiants
pubmed: 35888733
pii: metabo12070609
doi: 10.3390/metabo12070609
pmc: PMC9320524
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Cancer Cell. 2015 Oct 12;28(4):441-455
pubmed: 26461092
Arch Toxicol. 1987;60(1-3):144-9
pubmed: 3304204
J Biol Chem. 2000 Feb 4;275(5):3021-4
pubmed: 10652280
Adv Exp Med Biol. 2021;1301:41-57
pubmed: 34370287
Nat Commun. 2021 Nov 18;12(1):6729
pubmed: 34795270
Int J Mol Sci. 2021 Aug 18;22(16):
pubmed: 34445601
Cell Rep. 2016 Jan 26;14(3):411-421
pubmed: 26776506
Redox Biol. 2020 Sep;36:101670
pubmed: 32810738
Haematologica. 2019 Jul;104(7):1342-1354
pubmed: 30630985
Nat Rev Dis Primers. 2018 Mar 15;4:18010
pubmed: 29542687
Immunol Res. 2020 Aug;68(4):213-224
pubmed: 32681497
Front Cell Infect Microbiol. 2022 May 03;12:892232
pubmed: 35592652
Autoimmun Rev. 2020 Jul;19(7):102568
pubmed: 32376398
Free Radic Biol Med. 2021 Nov 1;175:18-27
pubmed: 34455040
Hepatology. 2021 Mar;73(3):1176-1193
pubmed: 32438524
Mol Metab. 2022 Jun;60:101470
pubmed: 35304332
Nat Commun. 2019 Jul 17;10(1):3145
pubmed: 31316058
Nature. 2006 Dec 21;444(7122):1027-31
pubmed: 17183312
JHEP Rep. 2020 Jul 28;2(6):100154
pubmed: 32995714
Nature. 2008 May 15;453(7193):396-400
pubmed: 18425110
Biochem J. 1998 Nov 15;336 ( Pt 1):201-5
pubmed: 9806901
Redox Biol. 2022 May;51:102276
pubmed: 35290903
Cell Metab. 2020 Jan 7;31(1):115-130.e6
pubmed: 31708445
Free Radic Biol Med. 2020 Nov 20;160:303-318
pubmed: 32846217
Front Cell Infect Microbiol. 2021 Oct 19;11:759435
pubmed: 34737978
Gastroenterol Hepatol Bed Bench. 2018 Spring;11(2):101-109
pubmed: 29910850
BMC Microbiol. 2021 Sep 28;21(1):259
pubmed: 34583649
Cell Rep Med. 2020 Nov 17;1(8):100144
pubmed: 33163981
Cell Res. 2016 Sep;26(9):1021-32
pubmed: 27514700
Mol Cell Biol. 2021 Aug 24;41(9):e0066820
pubmed: 34180713
J Nutr Biochem. 2022 Sep;107:109065
pubmed: 35609848
J Biol Chem. 2013 Jun 14;288(24):17791-802
pubmed: 23640898
Blood Cells Mol Dis. 2018 Mar;69:75-81
pubmed: 29032941
Blood. 2020 Dec 3;136(23):2691-2702
pubmed: 32659785
Lancet. 2020 Mar 28;395(10229):1054-1062
pubmed: 32171076
Nature. 2014 May 1;509(7498):105-9
pubmed: 24695223
J Pineal Res. 2021 Mar;70(2):e12704
pubmed: 33206394
Hemodial Int. 2017 Jun;21 Suppl 1:S6-S20
pubmed: 28296010
Nutrients. 2019 Apr 11;11(4):
pubmed: 30979076
Sci Rep. 2019 Feb 27;9(1):2918
pubmed: 30814647
Clin Epidemiol Glob Health. 2021 Jul-Sep;11:100727
pubmed: 33778183
Cell Metab. 2020 Jan 7;31(1):8-10
pubmed: 31951569
Blood Rev. 2009 May;23(3):95-104
pubmed: 18835072
Sci Rep. 2022 May 19;12(1):8398
pubmed: 35589811
Autoimmun Rev. 2020 Jul;19(7):102573
pubmed: 32387470
Biochem Biophys Res Commun. 2021 Oct 25;583:56-62
pubmed: 34735880
Am J Hematol. 2020 Jul;95(7):834-847
pubmed: 32282949
Am J Hum Genet. 2001 Jul;69(1):191-7
pubmed: 11389486
Cell. 2014 Jan 16;156(1-2):317-331
pubmed: 24439385
Microbiol Mol Biol Rev. 2017 Nov 8;81(4):
pubmed: 29118049
Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):E4922-30
pubmed: 24282296
Pharmaceuticals (Basel). 2018 Oct 23;11(4):
pubmed: 30360520
Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):
pubmed: 34161287
J Appl Microbiol. 2021 Dec;131(6):3018-3031
pubmed: 34008889
Nat Cell Biol. 2014 Dec;16(12):1180-91
pubmed: 25402683
J Biol Chem. 2016 Aug 12;291(33):17303-18
pubmed: 27302059
Cell Rep Med. 2022 Feb 25;3(3):100560
pubmed: 35474750
BMJ Case Rep. 2020 Dec 10;13(12):
pubmed: 33303503
Am J Emerg Med. 2020 Oct;38(10):2194-2202
pubmed: 33071092
Sci Rep. 2021 Oct 28;11(1):21242
pubmed: 34711879
Antioxidants (Basel). 2022 Jan 31;11(2):
pubmed: 35204181
Immunity. 2020 Jul 14;53(1):19-25
pubmed: 32610079
Genome Med. 2021 Apr 19;13(1):63
pubmed: 33874999
Circ Res. 2020 Jul 31;127(4):486-501
pubmed: 32349646
BMJ. 2018 Jun 13;361:k2179
pubmed: 29899036
Metallomics. 2014 Apr;6(4):748-73
pubmed: 24549403
Cell Death Differ. 2016 Mar;23(3):369-79
pubmed: 26794443
J Med Virol. 2021 Feb;93(2):1164-1170
pubmed: 32776538
EBioMedicine. 2022 Jul;81:104085
pubmed: 35636316
Biomed Pharmacother. 2021 Sep;141:111872
pubmed: 34246187
J Clin Invest. 2017 May 1;127(5):1786-1797
pubmed: 28375153
J Biol Chem. 2015 Sep 25;290(39):23523-7
pubmed: 26296885
Hematology. 2001;6(3):193-203
pubmed: 27420126
Eur J Neurol. 2015 Oct;22(10):1385-90
pubmed: 26095828
J Neuropathol Exp Neurol. 2021 Feb 22;80(3):220-228
pubmed: 33313661
Eur J Nutr. 2022 Jun;61(4):2067-2078
pubmed: 34997267
Pharmaceuticals (Basel). 2019 Jan 23;12(1):
pubmed: 30678075
Curr Opin Hematol. 2018 May;25(3):183-188
pubmed: 29461259
RNA. 2018 Apr;24(4):468-479
pubmed: 29295890
Nat Rev Microbiol. 2014 Oct;12(10):661-72
pubmed: 25198138
Science. 2008 May 30;320(5880):1207-10
pubmed: 18511687
Cell Metab. 2009 Feb;9(2):152-64
pubmed: 19147412
FASEB J. 2016 Jan;30(1):252-61
pubmed: 26370847
Oncol Lett. 2022 Jun;23(6):174
pubmed: 35497939
Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):8031-6
pubmed: 24843120
Lupus. 2015 Jan;24(1):82-9
pubmed: 25253568
Microbiome. 2021 May 7;9(1):104
pubmed: 33962692
Free Radic Biol Med. 2013 Dec;65:1174-1194
pubmed: 24036104
Diabetologia. 2020 Aug;63(8):1588-1602
pubmed: 32430665
Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):3143-8
pubmed: 10077651
J Intern Med. 2022 Apr 24;:
pubmed: 35466452
Biochim Biophys Acta Mol Cell Res. 2020 Nov;1867(11):118830
pubmed: 32835748
Mol Neurodegener. 2017 Oct 23;12(1):75
pubmed: 29061112
Pulmonology. 2021 Sep-Oct;27(5):423-437
pubmed: 33867315
Best Pract Res Clin Haematol. 2005 Jun;18(2):159-69
pubmed: 15737882
Elife. 2015 Oct 05;4:
pubmed: 26436293
Blood. 2022 Apr 21;139(16):2424-2425
pubmed: 35446376
Mol Cell. 2000 Feb;5(2):299-309
pubmed: 10882071
Blood. 2022 Apr 21;139(16):2547-2552
pubmed: 34990508
Nutrients. 2022 Jan 18;14(3):
pubmed: 35276770
FEBS Lett. 1978 Feb 1;86(1):136-8
pubmed: 620821
Lancet. 2020 Mar 28;395(10229):1033-1034
pubmed: 32192578
Ann Rheum Dis. 2020 Sep;79(9):1143-1151
pubmed: 32719045
Biochim Biophys Acta Mol Cell Res. 2021 Feb;1868(2):118913
pubmed: 33245979
Cancer Cell Int. 2021 Dec 29;21(1):709
pubmed: 34965856
Cell Host Microbe. 2020 Jun 10;27(6):992-1000.e3
pubmed: 32320677
Arch Biochem Biophys. 2021 Mar 30;700:108695
pubmed: 33232715
Cells. 2022 Mar 13;11(6):
pubmed: 35326435
Hepatology. 2017 Aug;66(2):449-465
pubmed: 28195347
Autophagy. 2016 Aug 2;12(8):1425-8
pubmed: 27245739
Cell Metab. 2010 Sep 8;12(3):273-82
pubmed: 20816093
Int Immunol. 2017 Nov 1;29(9):401-409
pubmed: 28541437
Pathol Int. 2022 Apr;72(4):242-251
pubmed: 35089637
Cell. 2012 May 25;149(5):1060-72
pubmed: 22632970
Mol Cell Biol. 2015 Nov 02;36(2):304-19
pubmed: 26527618
Front Pharmacol. 2014 Jun 13;5:124
pubmed: 24982634