In Silico Designed Multi-Epitope Immunogen "Tpme-VAC/LGCM-2022" May Induce Both Cellular and Humoral Immunity against

Treponema pallidum chimeric multi-epitope vaccine immunoinformatics sexually transmitted infection syphilis

Journal

Vaccines
ISSN: 2076-393X
Titre abrégé: Vaccines (Basel)
Pays: Switzerland
ID NLM: 101629355

Informations de publication

Date de publication:
25 Jun 2022
Historique:
received: 24 05 2022
revised: 21 06 2022
accepted: 23 06 2022
entrez: 27 7 2022
pubmed: 28 7 2022
medline: 28 7 2022
Statut: epublish

Résumé

Syphilis, a sexually transmitted infection caused by the spirochete

Identifiants

pubmed: 35891183
pii: vaccines10071019
doi: 10.3390/vaccines10071019
pmc: PMC9320004
pii:
doi:

Types de publication

Journal Article

Langues

eng

Références

Mol Immunol. 2019 Dec;116:106-116
pubmed: 31634814
Front Pediatr. 2020 Dec 15;8:569
pubmed: 33384972
Sci Rep. 2019 Feb 21;9(1):2517
pubmed: 30792446
Curr Top Microbiol Immunol. 2018;415:1-38
pubmed: 28849315
BMC Bioinformatics. 2007 Jan 05;8:4
pubmed: 17207271
BMC Bioinformatics. 2008 Dec 12;9 Suppl 12:S22
pubmed: 19091022
J Mol Biol. 2007 Sep 21;372(3):774-97
pubmed: 17681537
BMC Genomics. 2020 Jan 10;21(1):33
pubmed: 31924165
PLoS One. 2013 Sep 13;8(9):e73957
pubmed: 24058508
Int J Mol Sci. 2021 Mar 22;22(6):
pubmed: 33809918
Infect Immun. 2019 Jul 23;87(8):
pubmed: 31182617
Nat Protoc. 2012 Jul 19;7(8):1511-22
pubmed: 22814390
Bioinformatics. 2013 Mar 15;29(6):807-9
pubmed: 23343604
Immunogenetics. 2011 Jun;63(6):325-35
pubmed: 21305276
Epidemiol Infect. 2019 Jan;147:e143
pubmed: 30869043
Nat Protoc. 2015 Jun;10(6):845-58
pubmed: 25950237
J Comput Chem. 2004 Oct;25(13):1605-12
pubmed: 15264254
Immunogenetics. 2020 Feb;72(1-2):57-76
pubmed: 31761977
J Mol Biol. 1999 Sep 17;292(2):195-202
pubmed: 10493868
Lancet. 2017 Apr 15;389(10078):1550-1557
pubmed: 27993382
ChemMedChem. 2013 Mar;8(3):360-76
pubmed: 23316023
Exp Ther Med. 2018 Aug;16(2):1009-1013
pubmed: 30116352
PLoS Comput Biol. 2018 Nov 8;14(11):e1006457
pubmed: 30408041
BMC Bioinformatics. 2007 Oct 31;8:424
pubmed: 17973982
Curr Protoc Bioinformatics. 2015 Dec 17;52:5.8.1-5.8.15
pubmed: 26678386
Bioinformatics. 2017 Mar 15;33(6):929-931
pubmed: 28039165
Infect Immun. 2003 Oct;71(10):5605-12
pubmed: 14500480
Vaccine. 2014 Mar 20;32(14):1602-9
pubmed: 24135571
Immunology. 2018 Jul;154(3):394-406
pubmed: 29315598
BMC Bioinformatics. 2006 Mar 17;7:153
pubmed: 16545123
Nucleic Acids Res. 2012 Jul;40(Web Server issue):W294-7
pubmed: 22649060
Nat Rev Microbiol. 2016 Dec;14(12):744-759
pubmed: 27721440
Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W526-31
pubmed: 15980527
Iran J Parasitol. 2021 Jan-Mar;16(1):1-10
pubmed: 33786042
J Mol Model. 2014 Jun;20(6):2278
pubmed: 24878803
Int J Mol Sci. 2017 Feb 14;18(2):
pubmed: 28216574
Sex Transm Dis. 2014 Jul;41(7):440-6
pubmed: 24922103
Biol Direct. 2013 Dec 05;8:30
pubmed: 24304645
J Chem Inf Model. 2011 Oct 24;51(10):2778-86
pubmed: 21919503
Expert Rev Vaccines. 2017 Jan;16(1):37-44
pubmed: 27328030
Front Immunol. 2018 Apr 18;9:826
pubmed: 29720983
PLoS Comput Biol. 2013 Oct;9(10):e1003266
pubmed: 24204222
PLoS One. 2010 Apr 16;5(4):e9862
pubmed: 20419125
mBio. 2018 Jun 26;9(3):
pubmed: 29946052
Bioinformatics. 2017 Oct 01;33(19):3098-3100
pubmed: 28575391
BMC Bioinformatics. 2008 Dec 02;9:514
pubmed: 19055730
Nat Commun. 2017 Feb 01;8:14273
pubmed: 28145405

Auteurs

Lucas Gabriel Rodrigues Gomes (LGR)

Laboratory of Cellular and Molecular Genetics (LGCM), PG Program in Bioinformatics, Department of Genetics, Ecology, and Evolution, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), Belo Horizonte 31270-901, Brazil.

Thaís Cristina Vilela Rodrigues (TCV)

Laboratory of Cellular and Molecular Genetics (LGCM), PG Program in Bioinformatics, Department of Genetics, Ecology, and Evolution, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), Belo Horizonte 31270-901, Brazil.

Arun Kumar Jaiswal (AK)

Laboratory of Cellular and Molecular Genetics (LGCM), PG Program in Bioinformatics, Department of Genetics, Ecology, and Evolution, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), Belo Horizonte 31270-901, Brazil.

Roselane Gonçalves Santos (RG)

Laboratory of Cellular and Molecular Genetics (LGCM), PG Program in Bioinformatics, Department of Genetics, Ecology, and Evolution, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), Belo Horizonte 31270-901, Brazil.

Rodrigo Bentes Kato (RB)

Laboratory of Cellular and Molecular Genetics (LGCM), PG Program in Bioinformatics, Department of Genetics, Ecology, and Evolution, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), Belo Horizonte 31270-901, Brazil.

Debmalya Barh (D)

Laboratory of Cellular and Molecular Genetics (LGCM), PG Program in Bioinformatics, Department of Genetics, Ecology, and Evolution, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), Belo Horizonte 31270-901, Brazil.
Centre for Genomics and Applied Gene Technology, Institute of Integrative Omics and Applied Biotechnology (IIOAB), Nonakuri, Purba Medinipur 721172, West Bengal, India.

Khalid J Alzahrani (KJ)

Department of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.

Hamsa Jameel Banjer (HJ)

Department of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.

Siomar de Castro Soares (SC)

Department of Immunology, Microbiology, and Parasitology, Institute of Biological and Natural Sciences, Federal University of Triângulo Mineiro (UFTM), Uberaba 38025-180, Brazil.

Vasco Azevedo (V)

Laboratory of Cellular and Molecular Genetics (LGCM), PG Program in Bioinformatics, Department of Genetics, Ecology, and Evolution, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), Belo Horizonte 31270-901, Brazil.

Sandeep Tiwari (S)

Laboratory of Cellular and Molecular Genetics (LGCM), PG Program in Bioinformatics, Department of Genetics, Ecology, and Evolution, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), Belo Horizonte 31270-901, Brazil.

Classifications MeSH