Cardiovascular Diseases in the Digital Health Era: A Translational Approach from the Lab to the Clinic.
cardiovascular diseases
digital health
translational medicine
Journal
Biotech (Basel (Switzerland))
ISSN: 2673-6284
Titre abrégé: BioTech (Basel)
Pays: Switzerland
ID NLM: 9918383086206676
Informations de publication
Date de publication:
30 Jun 2022
30 Jun 2022
Historique:
received:
18
05
2022
revised:
19
06
2022
accepted:
27
06
2022
entrez:
27
7
2022
pubmed:
28
7
2022
medline:
28
7
2022
Statut:
epublish
Résumé
Translational science has been introduced as the nexus among the scientific and the clinical field, which allows researchers to provide and demonstrate that the evidence-based research can connect the gaps present between basic and clinical levels. This type of research has played a major role in the field of cardiovascular diseases, where the main objective has been to identify and transfer potential treatments identified at preclinical stages into clinical practice. This transfer has been enhanced by the intromission of digital health solutions into both basic research and clinical scenarios. This review aimed to identify and summarize the most important translational advances in the last years in the cardiovascular field together with the potential challenges that still remain in basic research, clinical scenarios, and regulatory agencies.
Identifiants
pubmed: 35892928
pii: biotech11030023
doi: 10.3390/biotech11030023
pmc: PMC9326743
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Subventions
Organisme : Instituto de Salud Carlos III
ID : PI16/01123, , DTS16/0160, PI17/01059, PI19/00161, PI20/01618, DTS21/00064 and PI18/01895
Organisme : Instituto de Salud Carlos III
ID : Red TERCEL RETIC RD16/0011/0029
Organisme : Instituto de Salud Carlos III
ID : RICORS RD21/0017 and TERAV (Group: 002)
Organisme : Comunidad de Madrid
ID : S2017/BMD-3962, Avancell-CM
Organisme : Centro de Investigación en Red en Enfermedades Cardiovasculares
Organisme : European Union
ID : H2020 Grant Agreement No.874827 (Brav3)
Références
Am J Physiol Heart Circ Physiol. 2021 Dec 1;321(6):H1056-H1073
pubmed: 34623181
Eur Heart J. 2016 Jun 14;37(23):1789-98
pubmed: 27055812
Physiol Meas. 2018 Sep 27;39(9):094008
pubmed: 30187894
J Am Coll Radiol. 2019 Sep;16(9 Pt A):1179-1189
pubmed: 31151893
J R Soc Med. 2011 Dec;104(12):510-20
pubmed: 22179294
Europace. 2022 Jul 15;24(6):979-1005
pubmed: 35368065
J Transl Med. 2003 Aug 7;1(1):2
pubmed: 14527343
Sci Rep. 2020 Sep 29;10(1):16057
pubmed: 32994452
ScientificWorldJournal. 2015;2015:685690
pubmed: 25853146
Exp Physiol. 2009 May;94(5):563-77
pubmed: 19270037
J Vis Exp. 2011 Feb 16;(48):
pubmed: 21372786
Eur Heart J. 2021 Sep 7;42(34):3227-3337
pubmed: 34458905
Nat Med. 2021 Nov 4;:
pubmed: 34737437
Toxicol Sci. 2019 Jul 1;170(1):167-179
pubmed: 30912807
Circ Res. 2015 Jan 2;116(1):116-26
pubmed: 25552691
J Thorac Cardiovasc Surg. 2010 Aug;140(2):395-9
pubmed: 20570291
Circulation. 2020 Oct 20;142(16):1521-1523
pubmed: 33074761
Biology (Basel). 2021 Aug 28;10(9):
pubmed: 34571716
Cell Transplant. 2018 Jul;27(7):1047-1067
pubmed: 29947252
J Pharmacol Toxicol Methods. 2016 Sep-Oct;81:251-62
pubmed: 27060526
Int J Mol Sci. 2022 Apr 11;23(8):
pubmed: 35457044
J Heart Lung Transplant. 2014 Nov;33(11):1180-3
pubmed: 25239034
JAMA. 2007 Jan 24;297(4):403-6
pubmed: 17244837
Nurs Res Pract. 2012;2012:792519
pubmed: 22474583
Biomaterials. 2015 Aug;61:279-89
pubmed: 26005766
J Geriatr Cardiol. 2019 Aug;16(8):585-591
pubmed: 31555325
Nat Protoc. 2016 Mar;11(3):542-52
pubmed: 26890681
J Surg Res. 2004 Jan;116(1):124-8
pubmed: 14732358
Am J Physiol Heart Circ Physiol. 2021 Apr 1;320(4):H1337-H1347
pubmed: 33513086
Sci Rep. 2020 May 15;10(1):8029
pubmed: 32415191
Clin Transl Sci. 2021 Sep;14(5):1629-1647
pubmed: 33982407
Trials. 2021 Nov 12;22(1):795
pubmed: 34772433
Stem Cell Reports. 2019 Oct 8;13(4):657-668
pubmed: 31564645
Prog Biophys Mol Biol. 2017 Oct;129:53-64
pubmed: 27899270
J Law Med Ethics. 2020 Mar;48(1):7-10
pubmed: 32342780
Front Physiol. 2021 Dec 06;12:768468
pubmed: 34938202
Cytotechnology. 2017 Oct;69(5):785-800
pubmed: 28397099
Cell Rep. 2017 Jan 10;18(2):571-582
pubmed: 28076798
Nat Rev Cardiol. 2021 Jul;18(7):457-458
pubmed: 33824486
N Engl J Med. 2010 Apr 8;362(14):1304-11
pubmed: 20375407
Comput Biol Med. 2018 Nov 1;102:411-420
pubmed: 30245122
J Proteom Genom Res. 2017;2(1):1-12
pubmed: 29367937
Br J Cancer. 2022 Jan;126(1):4-9
pubmed: 34837074
JACC Basic Transl Sci. 2019 Nov 25;4(7):845-854
pubmed: 31998852
Int J Mol Sci. 2021 Aug 26;22(17):
pubmed: 34502146
Prog Biophys Mol Biol. 2017 Nov;130(Pt B):212-222
pubmed: 28688751
Front Bioeng Biotechnol. 2020 Aug 11;8:955
pubmed: 32850768
Ann Transl Med. 2016 May;4(9):181
pubmed: 27275494
Brain Commun. 2020 Jul 09;2(2):fcaa096
pubmed: 33134913
Circ Res. 2019 Mar 15;124(6):938-951
pubmed: 30870121
Cell Biochem Funct. 2016 Apr;34(3):113-32
pubmed: 26914991
Heart. 2020 Mar;106(5):399-400
pubmed: 31974212
Br J Pharmacol. 2006 Dec;149(7):845-60
pubmed: 17031389
Haematologica. 2021 May 01;106(5):1354-1367
pubmed: 32327499
Clin Pharmacol Ther. 2019 Apr;105(4):943-953
pubmed: 30447156
Cardiovasc Res. 2021 May 25;117(6):1428-1433
pubmed: 33258961
ESC Heart Fail. 2021 Jun;8(3):2306-2309
pubmed: 33652498
Front Physiol. 2017 Sep 12;8:668
pubmed: 28955244
Lab Anim (NY). 2016 Feb;45(2):67-74
pubmed: 26814353
Eur J Prev Cardiol. 2016 Oct;23(2 suppl):5-12
pubmed: 27892420
Sci Rep. 2020 Oct 6;10(1):16579
pubmed: 33024165
Circ Res. 2018 Jan 19;122(2):310-318
pubmed: 29348252
Methods Mol Biol. 2018;1816:309-325
pubmed: 29987830
Clin Transl Med. 2013 Jul 27;2(1):14
pubmed: 23889844
Heart Rhythm. 2016 Dec;13(12):2358-2365
pubmed: 27569443
Circulation. 2016 Dec 13;134(24):1913-1914
pubmed: 27881558
Brief Bioinform. 2020 Dec 1;21(6):2031-2051
pubmed: 31802103
Diabetes Care. 2022 Jan 1;45(1):204-212
pubmed: 34716214
Front Cardiovasc Med. 2021 Dec 08;8:707070
pubmed: 34957228
Nat Commun. 2016 May 10;7:11437
pubmed: 27164184
Acad Med. 2010 Mar;85(3):470-5
pubmed: 20182120
J Cardiovasc Electrophysiol. 2019 Sep;30(9):1602-1609
pubmed: 31190453
Eur Heart J. 2020 Jun 1;41(21):2036
pubmed: 32413901
J Am Heart Assoc. 2019 Feb 5;8(3):e010115
pubmed: 30675825
Korean J Radiol. 2019 Mar;20(3):405-410
pubmed: 30799571
Eur Heart J. 2017 Sep 1;38(33):2532-2546
pubmed: 28575280