A Guide to a Pharmacist-Led Pharmacogenetic Testing and Counselling Service in an Interprofessional Healthcare Setting.
clinical pharmacy
community pharmacy
hospital pharmacy
medication review
personalized medicine
pharmaceutical care
pharmacogenomics
pharmacy service
primary care
secondary care
Journal
Pharmacy (Basel, Switzerland)
ISSN: 2226-4787
Titre abrégé: Pharmacy (Basel)
Pays: Switzerland
ID NLM: 101678532
Informations de publication
Date de publication:
19 Jul 2022
19 Jul 2022
Historique:
received:
28
06
2022
revised:
14
07
2022
accepted:
15
07
2022
entrez:
27
7
2022
pubmed:
28
7
2022
medline:
28
7
2022
Statut:
epublish
Résumé
Genetic predisposition is one factor influencing interindividual drug response. Pharmacogenetic information can be used to guide the selection and dosing of certain drugs. However, the implementation of pharmacogenetics (PGx) in clinical practice remains challenging. Defining a formal structure, as well as concrete procedures and clearly defined responsibilities, may facilitate and increase the use of PGx in clinical practice. Over 140 patient cases from an observational study in Switzerland formed the basis for the design and refinement of a pharmacist-led pharmacogenetics testing and counselling service (PGx service) in an interprofessional setting. Herein, we defined a six-step approach, including: (1) patient referral; (2) pre-test-counselling; (3) PGx testing; (4) medication review; (5) counselling; (6) follow-up. The six-step approach supports the importance of an interprofessional collaboration and the role of pharmacists in PGx testing and counselling across healthcare settings.
Identifiants
pubmed: 35893724
pii: pharmacy10040086
doi: 10.3390/pharmacy10040086
pmc: PMC9326676
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Stiftung zur Förderung des pharmazeutischen Nachwuchses in Basel
ID : n.a.
Références
Annu Rev Nurs Res. 2000;18:48-90
pubmed: 10918932
Pharmacol Ther. 2013 Apr;138(1):103-41
pubmed: 23333322
Clin Pharmacol Ther. 2020 Jan;107(1):57-61
pubmed: 31696505
Pharmacy (Basel). 2021 Dec 16;9(4):
pubmed: 34941633
Pharmacogenomics J. 2021 Aug;21(4):423-434
pubmed: 33070160
Pharmgenomics Pers Med. 2022 May 09;15:465-475
pubmed: 35586477
J Clin Med. 2020 Sep 07;9(9):
pubmed: 32906709
Pharmacy (Basel). 2022 Jul 19;10(4):
pubmed: 35893724
J Clin Med. 2020 Jul 17;9(7):
pubmed: 32708920
Trials. 2021 Dec 14;22(1):919
pubmed: 34906208
Clin Pharmacol Ther. 2017 Mar;101(3):341-358
pubmed: 28027596
Pharmacogenomics. 2020 Nov;21(16):1145-1150
pubmed: 33124517
Pharmgenomics Pers Med. 2021 Feb 19;14:279-286
pubmed: 33642872
Clin Pharmacol Ther. 2011 May;89(5):662-73
pubmed: 21412232
Ment Health Clin. 2020 Jul 2;10(4):254-258
pubmed: 32685338
BMJ. 2014 Mar 07;348:g1687
pubmed: 24609605
BMC Health Serv Res. 2016 Apr 23;16:145
pubmed: 27108410
Int J Clin Pharm. 2018 Oct;40(5):1199-1208
pubmed: 30073611
Int J Mol Sci. 2021 Jun 17;22(12):
pubmed: 34204223
Pharmacy (Basel). 2020 Mar 28;8(2):
pubmed: 32231164
Life (Basel). 2021 Jul 09;11(7):
pubmed: 34357045
Pharmacogenet Genomics. 2009 Jul;19(7):559-62
pubmed: 19512959
Clin Pharmacol Ther. 2012 Oct;92(4):414-7
pubmed: 22992668
Pharmacy (Basel). 2021 Sep 06;9(3):
pubmed: 34564559
J Pers Med. 2020 Dec 21;10(4):
pubmed: 33371313
Transl Psychiatry. 2022 Mar 14;12(1):101
pubmed: 35288545
Genes (Basel). 2019 May 29;10(6):
pubmed: 31146504
BMC Psychiatry. 2017 Feb 8;17(1):60
pubmed: 28178974