DNA-Vaccine-Induced Immune Response Correlates with Lower Viral SARS-CoV-2 Titers in a Ferret Model.

DNA vaccines SARS-CoV-2 ferrets immune responses

Journal

Vaccines
ISSN: 2076-393X
Titre abrégé: Vaccines (Basel)
Pays: Switzerland
ID NLM: 101629355

Informations de publication

Date de publication:
25 Jul 2022
Historique:
received: 18 06 2022
revised: 15 07 2022
accepted: 20 07 2022
entrez: 27 7 2022
pubmed: 28 7 2022
medline: 28 7 2022
Statut: epublish

Résumé

The COVID-19 pandemic is entering a new era with the approval of many SARS-CoV-2 vaccines. In spite of the restoration of an almost normal way of life thanks to the immune protection elicited by these innovative vaccines, we are still facing high viral circulation, with a significant number of deaths. To further explore alternative vaccination platforms, we developed COVID-

Identifiants

pubmed: 35893826
pii: vaccines10081178
doi: 10.3390/vaccines10081178
pmc: PMC9332309
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : TRANSVAC2
ID : TRANSVAC2 Infrastructure Call 2002-08-Covivax

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Auteurs

Mirco Compagnone (M)

Neomatrix, 00128 Rome, Italy.

Silvia Marchese (S)

INGM-Istituto Nazionale di Genetica Molecolare "Romeo ed Enrica Invernizzi", 20122 Milan, Italy.

Micol Ravà (M)

Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.

Kathryn Ryan (K)

UK Health Security Agency (UKHSA), Porton Down, Salisbury SP4 0JG, UK.

Yper Hall (Y)

UK Health Security Agency (UKHSA), Porton Down, Salisbury SP4 0JG, UK.

Emma Rayner (E)

UK Health Security Agency (UKHSA), Porton Down, Salisbury SP4 0JG, UK.

Francisco J Salguero (FJ)

UK Health Security Agency (UKHSA), Porton Down, Salisbury SP4 0JG, UK.

Jemma Paterson (J)

UK Health Security Agency (UKHSA), Porton Down, Salisbury SP4 0JG, UK.

Matteo Iannacone (M)

Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Vita-Salute San Raffaele University, 20132 Milan, Italy.
Experimental Imaging Centre, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.

Raffaele De Francesco (R)

INGM-Istituto Nazionale di Genetica Molecolare "Romeo ed Enrica Invernizzi", 20122 Milan, Italy.
Department of Pharmacological and Biomolecular Sciences (DiSFeB), University of Milan, 20133 Milan, Italy.

Luigi Aurisicchio (L)

Neomatrix, 00128 Rome, Italy.
Takis, 00128 Rome, Italy.
Evvivax, 00128 Rome, Italy.

Fabio Palombo (F)

Neomatrix, 00128 Rome, Italy.
Takis, 00128 Rome, Italy.

Classifications MeSH