[Recurrent epistaxis with coagulation disorders in a boy aged 2 years].

2岁男孩反复鼻衄伴凝血功能异常.

Journal

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
ISSN: 1008-8830
Titre abrégé: Zhongguo Dang Dai Er Ke Za Zhi
Pays: China
ID NLM: 100909956

Informations de publication

Date de publication:
15 Jul 2022
Historique:
entrez: 27 7 2022
pubmed: 28 7 2022
medline: 29 7 2022
Statut: ppublish

Résumé

A boy, aged 2 years and 5 months, had recurrent epistaxis, and the coagulation function examination showed that activated partial thromboplastin time (APTT) was significantly prolonged. Further laboratory examinations showed that the prolonged APTT was not immediately corrected in the APTT correction test, with positive lupus anticoagulant and low prothrombin activity. The boy was diagnosed with hypoprothrombinemia-lupus anticoagulant syndrome. The condition was improved after treatment with glucocorticoid, immunoglobulin, and vitamin K 2岁5个月男孩,反复鼻衄,凝血功能发现活化部分凝血活酶时间(activated partial thromboplastin time,APTT)明显延长,进一步实验室检查提示APTT纠正试验为即刻不能纠正,狼疮抗凝物检测阳性,凝血酶原活性低,诊断为低凝血酶原血症-狼疮抗凝物综合征。予激素、丙种球蛋白、维生素K

Autres résumés

Type: Publisher (chi)
2岁5个月男孩,反复鼻衄,凝血功能发现活化部分凝血活酶时间(activated partial thromboplastin time,APTT)明显延长,进一步实验室检查提示APTT纠正试验为即刻不能纠正,狼疮抗凝物检测阳性,凝血酶原活性低,诊断为低凝血酶原血症-狼疮抗凝物综合征。予激素、丙种球蛋白、维生素K

Identifiants

pubmed: 35894199
pii: 1008-8830(2022)07-0817-04
doi: 10.7499/j.issn.1008-8830.2203060
pmc: PMC9336632
pii:
doi:

Substances chimiques

Lupus Coagulation Inhibitor 0
Prothrombin 9001-26-7

Types de publication

Case Reports Journal Article

Langues

chi

Sous-ensembles de citation

IM

Pagination

817-820

Références

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pubmed: 27473743
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pubmed: 33509039
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pubmed: 30369197
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pubmed: 33858037
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pubmed: 2456797
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Blood. 1983 Apr;61(4):684-92
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Auteurs

Jia-Zhuo Li (JZ)

Department of Hematology and Oncology, First Affiliated Hospital of Hunan Normal University/Children's Medical Center, Hunan Provincial People's Hospital, Changsha 410005, China.

Xin Tian (X)

Department of Hematology and Oncology, First Affiliated Hospital of Hunan Normal University/Children's Medical Center, Hunan Provincial People's Hospital, Changsha 410005, China.

Xiang-Ling He (XL)

Department of Hematology and Oncology, First Affiliated Hospital of Hunan Normal University/Children's Medical Center, Hunan Provincial People's Hospital, Changsha 410005, China.

Cheng-Guang Zhu (CG)

Department of Hematology and Oncology, First Affiliated Hospital of Hunan Normal University/Children's Medical Center, Hunan Provincial People's Hospital, Changsha 410005, China.

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Classifications MeSH