Case Report: Chemoradiation with Paclitaxel and Carboplatin Unveiling Leprosy Type 1 Downgrading Reaction.
Journal
The American journal of tropical medicine and hygiene
ISSN: 1476-1645
Titre abrégé: Am J Trop Med Hyg
Pays: United States
ID NLM: 0370507
Informations de publication
Date de publication:
13 07 2022
13 07 2022
Historique:
received:
02
02
2022
accepted:
08
04
2022
entrez:
27
7
2022
pubmed:
28
7
2022
medline:
30
7
2022
Statut:
epublish
Résumé
Type 1 lepra reaction (T1R) is a major complication seen in nonpolar forms of leprosy and leads to significant morbidity. The classification of T1R as up and downgrading, based on previously defined histopathological criteria (by Ridley), has therapeutic and prognostic implications. The trigger factors for these reactions are poorly described, especially in case of downgrading T1R and we describe a case of leprosy reaction that was possibly triggered by chemoradiation and elucidate the possible mechanism.
Identifiants
pubmed: 35895355
doi: 10.4269/ajtmh.22-0099
pmc: PMC9294680
doi:
Substances chimiques
Carboplatin
BG3F62OND5
Paclitaxel
P88XT4IS4D
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
94-96Références
Expert Rev Anti Infect Ther. 2011 Jun;9(6):701-10
pubmed: 21692674
Int J Mycobacteriol. 2019 Jul-Sep;8(3):305-308
pubmed: 31512611
Oncoimmunology. 2013 Oct 1;2(10):e27025
pubmed: 24353914
PLoS One. 2018 Jun 8;13(6):e0196853
pubmed: 29883464
Cancer Lett. 2015 Jan 1;356(1):82-90
pubmed: 24125863
Immunotherapy. 2017 Sep;9(11):913-927
pubmed: 29338609
Int J Lepr Other Mycobact Dis. 1981 Dec;49(4):383-92
pubmed: 7200465
Clin Infect Dis. 2006 Jul 15;43(2):e19-22
pubmed: 16779736
J Am Acad Dermatol. 1994 Feb;30(2 Pt 2):313-5
pubmed: 8294589
PLoS Negl Trop Dis. 2016 Apr 01;10(4):e0004592
pubmed: 27035913
Clin Immunol. 2008 Nov;129(2):219-29
pubmed: 18771959