Role of the PD-1 and PD-L1 axis in COVID-19.

B7-H1 Antigen / metabolism COVID-19 Humans Programmed Cell Death 1 Receptor / metabolism
COVID-19 PD-1 PD-L1 SARS-CoV-2 adaptive immune cells immune checkpoint molecules innate immune cells

Journal

Future microbiology
ISSN: 1746-0921
Titre abrégé: Future Microbiol
Pays: England
ID NLM: 101278120

Informations de publication

Date de publication:
09 2022
Historique:
pubmed: 29 7 2022
medline: 17 8 2022
entrez: 28 7 2022
Statut: ppublish

Résumé

Tweetable abstract Severe COVID-19 patients display dysregulated expression of checkpoint molecules PD-1 and its ligand PD-L1, suggesting that these checkpoint molecules could be considered as prognostic markers and therapeutic targets in severe cases of COVID-19.

Identifiants

DOI: 10.2217/fmb-2022-0103 PMID: 35899493 PMC: PMC9332906
pubmed: 35899493
doi: 10.2217/fmb-2022-0103
pmc: PMC9332906
doi:

Substances chimiques

B7-H1 Antigen 0
Programmed Cell Death 1 Receptor 0

Types de publication

Editorial Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

985-988

Auteurs

Srinivasa R Bonam (S)

Department of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.
ORCID: 0000-0002-2888-2418

Haitao Hu (H)

Department of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Institute for Human Infections & Immunity, Sealy Institute for Vaccine Sciences, University of Texas Medical Branch, Galveston, TX 77555, USA.
ORCID: 0000-0002-6964-2314

Jagadeesh Bayry (J)

Department of Biological Sciences & Engineering, Indian Institute of Technology Palakkad, Palakkad, 678623, India.
ORCID: 0000-0003-0498-9808

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Antigènes B7 › Antigène CD274 › Role of the PD-1 and PD-L1 axis in COVID-19.
questionsmedicales.fr › Maladies de l'appareil respiratoire › Infections de l'appareil respiratoire › Pneumopathie infectieuse › Pneumopathie virale › COVID-19 › Role of the PD-1 and PD-L1 axis in COVID-19.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Role of the PD-1 and PD-L1 axis in COVID-19.
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Antigènes de différenciation › Antigènes de différenciation des lymphocytes T › Récepteur-1 de mort cellulaire programmée › Role of the PD-1 and PD-L1 axis in COVID-19.