Intraocular lymphoma masquerading as unilateral hypopyon anterior uveitis: a case report.
Anterior uveitis
Diffuse large B-cell lymphoma
Hypopyon uveitis
Masquerade syndrome
Vitreoretinal lymphoma
Journal
Journal of ophthalmic inflammation and infection
ISSN: 1869-5760
Titre abrégé: J Ophthalmic Inflamm Infect
Pays: Germany
ID NLM: 101553216
Informations de publication
Date de publication:
28 Jul 2022
28 Jul 2022
Historique:
received:
12
03
2022
accepted:
17
07
2022
entrez:
28
7
2022
pubmed:
29
7
2022
medline:
29
7
2022
Statut:
epublish
Résumé
To report an unusual case of unilateral anterior segment large B-cell intraocular lymphoma (IOL) presenting as a recurrent hypopyon anterior uveitis. A 55-year-old female was referred because of recurrent unilateral anterior hypopyon uveitis with partial response to topical corticosteroid. All of the laboratory tests, review of systems and ocular sampling results were unremarkable. Given a high concern for masquerades syndromes, cytological specimens were obtained 3 times and the last sample showed large B cell lymphoma. First, it appeared confined to the eye and initially responded favorably to local chemotherapy (methotrexate and rituximab) but later went on to develop systemic involvement. CNS lymphoma was detected on the third brain MRI 6 months following ocular involvement. At this time, systemic chemotherapy was started. In the last 18 months' follow-up, visual acuity was 20/30 in the right eye without posterior segment or fellow eye involvement. Unusual presentation of intraocular lymphoma as a unilateral isolated anterior hypopyon uveitis should be kept in mind. This report emphasizes the importance of precise work-ups and multiple ocular biopsies to confirm the diagnosis of intraocular lymphoma.
Identifiants
pubmed: 35900606
doi: 10.1186/s12348-022-00302-5
pii: 10.1186/s12348-022-00302-5
pmc: PMC9334462
doi:
Types de publication
Journal Article
Langues
eng
Pagination
25Informations de copyright
© 2022. The Author(s).
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