The effect of farming environment on asthma; time dependent or universal?

Agriculture Asthma / epidemiology Farms Humans Logistic Models Prevalence
Asthma ECRHS Farm opbringing RHINE RHINESSA

Journal

European journal of epidemiology
ISSN: 1573-7284
Titre abrégé: Eur J Epidemiol
Pays: Netherlands
ID NLM: 8508062

Informations de publication

Date de publication:
Aug 2022
Historique:
received: 15 03 2021
accepted: 20 06 2022
pubmed: 29 7 2022
medline: 14 9 2022
entrez: 28 7 2022
Statut: ppublish

Résumé

The increasing prevalence of asthma is linked to westernization and urbanization. Farm environments have been associated with a lower risk of asthma development. However, this may not be universal, as the association differs across birth cohorts and farming methods. The aim of this study was to investigate the associations of farm upbringing with asthma in different generations and at different times in history. The study population consisted of three generations: 13,868 subjects participating in the ECRHS in 2010, their 9,638 parents, and their 8,885 offspring participating in RHINESSA in 2013. Information on place of upbringing and self-reported ever asthma was provided via questionnaires. Logistic regression was performed including subgroup analysis stratified by generation and birthyear into ten-year-intervals. The prevalence of asthma increased from 8% among grandparents to 13% among parents and to 18% among offspring. An overall analysis showed an inverse association of farm upbringing on the risk of asthma (OR = 0.64; 95%CI 0.55-0.74). Subgroup analysis stratified into ten-year-intervals showed a tendency towards a more pronounced inverse association between growing up on a farm and asthma among subjects born in the 1940s (0.74; 0.48-1.12), 1950s (0.70; 0.54-0.90) and 1960s (0.70; 0.52-0.93). For subjects born in 1970 and thereafter this association appeared less consistent. While growing up on a farm was associated with a reduced risk of developing asthma in participants born between 1945-1999, this was mainly driven by generations born from 1945 to 1973.

Identifiants

DOI: 10.1007/s10654-022-00893-2 PMID: 35900634
pubmed: 35900634
doi: 10.1007/s10654-022-00893-2
pii: 10.1007/s10654-022-00893-2
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

779-788

Subventions

Organisme : The Faculty of Health, Aarhus University, Denmark
ID : 240008
Organisme : The Wood Dust Foundation
ID : 444508795
Organisme : The Norwegian Research Council
ID : 214123
Organisme : The Norwegian Research Council
ID : 230827/F20
Organisme : The Norwegian Research Council
ID : 228174
Organisme : The Norwegian Research Council
ID : 135773/330
Organisme : HelseVest Norway
ID : 911 631
Organisme : The Estonian Science Foundation
ID : 4350
Organisme : The Estonian Research Council
ID : PUT562
Organisme : SEPAR Spain, Sociedad Española de Neumologia y Cirugía Toracica Spain and Horizon2020 PHC1
ID : 633212

Informations de copyright

© 2022. Springer Nature B.V.

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Auteurs

Marie Kjær Madsen (MK)

Department of Public Health, Danish Ramazzini Centre, Aarhus University, Aarhus, Denmark. mariekjaer94@gmail.com.
ORCID: 0000-0002-0528-604X

Vivi Schlünssen (V)

Department of Public Health, Danish Ramazzini Centre, Aarhus University, Aarhus, Denmark.
National Research Centre for Working Environment, Copenhagen, Denmark.

Cecilie Svanes (C)

Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway.

Ane Johannessen (A)

Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway.

Nils Oskar Jõgi (NO)

Department of Clinical Science, University of Bergen, Bergen, Norway.

Mathias Holm (M)

Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Christer Janson (C)

Department of Medical Sciences: Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.

Antonio Pereira-Vega (A)

Pneumology Service of the Juan Ramón Jiménez Hospital, Huelva, Spain.

Adrian J Lowe (AJ)

Allergy and Lung Health Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia.

Karl A Franklin (KA)

Department of Surgical and Preoperative Sciences, Umeå University, 901 85, Surgery, Umeå, Sweden.

Andrei Malinovschi (A)

Department of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden.

Torben Sigsgaard (T)

Department of Public Health, Danish Ramazzini Centre, Aarhus University, Aarhus, Denmark.

Michael J Abramson (MJ)

School of Public Health & Preventive Medicine, Monash University, Melbourne, Australia.

Randi Bertelsen (R)

Department of Clinical Science, University of Bergen, Bergen, Norway.
Oral Health Centre of Expertise in Western Norway, Bergen, Norway.

Anna Oudin (A)

Department of Public Health and Clinical Medicine, Sustainable Health, Umeå University, Umeå, Sweden.

Thorarinn Gislason (T)

Department of Sleep, Landspitali University Hospital, Reykjavík, Iceland.
Medical Faculty, University of Iceland, Reykjavík, Iceland.

Signe Timm (S)

Department of Public Health, Danish Ramazzini Centre, Aarhus University, Aarhus, Denmark.

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Classifications MeSH

questionsmedicales.fr › Technologie, industrie et agriculture › Agriculture › The effect of farming environment on asthma;...
questionsmedicales.fr › Maladies du système immunitaire › Hypersensibilité › Hypersensibilité immédiate › Hypersensibilité respiratoire › Asthme › The effect of farming environment on asthma;...
questionsmedicales.fr › Établissements non médicaux publics ou privés › Installations industrielles et de fabrication › Fermes › The effect of farming environment on asthma;...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The effect of farming environment on asthma;...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Analyse de régression › Modèles logistiques › The effect of farming environment on asthma;...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Registre civil › Morbidité › Prévalence › The effect of farming environment on asthma;...