Developing services to support the delivery of care to people with early-onset type 2 diabetes.


Journal

Diabetic medicine : a journal of the British Diabetic Association
ISSN: 1464-5491
Titre abrégé: Diabet Med
Pays: England
ID NLM: 8500858

Informations de publication

Date de publication:
10 2022
Historique:
revised: 16 05 2022
received: 01 12 2021
accepted: 26 07 2022
pubmed: 29 7 2022
medline: 15 9 2022
entrez: 28 7 2022
Statut: ppublish

Résumé

Early-onset type 2 diabetes occurring in childhood or early adulthood carries a significant excess burden of microvascular diabetes complications, cardiovascular disease and premature death, compared to later onset type 2 diabetes along with adverse pregnancy outcomes in women of child-bearing age. National audit data in England reveal that 122,780 individuals under the age of 40 years are currently living with type 2 diabetes, with an over-representation of people from minority ethnicities and those in the most socioeconomically deprived quintiles. A diagnosis of type 2 diabetes earlier in life poses some unique challenges to healthcare providers that are not routinely encountered when type 2 diabetes presents later. These include; (1) the need to ensure correct diabetes classification in an age group that carries a higher probability of other types of diabetes, (2) overcoming difficulties in engaging with individuals who are of working age or in full-time education, (3) appreciating and addressing the lower attainment of diabetes treatment targets and (4) proactively supporting women of child-bearing age to optimise their future pregnancy outcomes through better preparation for pregnancy, including achieving optimum glycaemic control at the time of conception. Meanwhile, approaches to prevent type 2 diabetes in younger age groups are challenged by difficulties in identifying those at highest risk, by poorer attendance at lifestyle interventions to prevent or delay the onset of type 2 diabetes and by attenuation of associated weight loss in those that do attend. In this article, we discuss the importance of recognising and addressing the distinct challenges in delivering healthcare to those with early-onset type 2 diabetes, the greater challenges in preventing type 2 diabetes at younger ages, and key components of strategies that might address these challenges to drive improvements in pregnancy outcomes, microvascular and cardiovascular outcomes.

Identifiants

pubmed: 35900910
doi: 10.1111/dme.14927
pmc: PMC9542364
doi:

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e14927

Informations de copyright

© 2022 The Authors. Diabetic Medicine published by John Wiley & Sons Ltd on behalf of Diabetes UK.

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Auteurs

Shivani Misra (S)

Division of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Department of Diabetes and Endocrinology, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.
National Diabetes Audit Programme, NHS England and NHS Improvement, London, UK.

David Gable (D)

Department of Diabetes and Endocrinology, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.

Kamlesh Khunti (K)

Diabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, UK.

Emma Barron (E)

NHS England and NHS Improvement, London, UK.

Bob Young (B)

National Diabetes Audit Programme, NHS England and NHS Improvement, London, UK.

Partha Kar (P)

NHS England and NHS Improvement, London, UK.
Portsmouth Hospitals NHS Trust, Portsmouth, UK.

Jonathan Valabhji (J)

Division of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Department of Diabetes and Endocrinology, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.
NHS England and NHS Improvement, London, UK.

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