Detection of Cd
Amyloid
Cadmium ion
Electrochemical sensor
Heavy metal ion
Lead ion
Square Wave Anodic Stripping Voltammetry (SWASV)
Journal
Bioelectrochemistry (Amsterdam, Netherlands)
ISSN: 1878-562X
Titre abrégé: Bioelectrochemistry
Pays: Netherlands
ID NLM: 100953583
Informations de publication
Date de publication:
Oct 2022
Oct 2022
Historique:
received:
15
04
2022
revised:
18
07
2022
accepted:
19
07
2022
pubmed:
29
7
2022
medline:
25
8
2022
entrez:
28
7
2022
Statut:
ppublish
Résumé
Heavy metal ions are toxic to humans and can further interact with amyloid in the human body to produce amyloid plaques, which disrupt neurotransmitter function and are linked to Alzheimer's and Parkinson's diseases. In this study, we developed an amyloid oligomer-reduced graphene oxide composite (AOrGOC) electrochemical sensor for effective heavy metal ion detection based on square-wave anodic stripping voltammetry. The reactivity between amyloids and heavy metal ions was studied by analyzing the stripping current for different amyloids (lysozyme, bovine serum albumin, and β-lactoglobulin) and amyloid growth types (monomers, oligomers, and fibrils). Reduced graphene oxide was used to improve the sensitivity of the sensor. The AOrGOC sensor exhibited the detection limits of 86.0 and 9.5 nM for Cd
Identifiants
pubmed: 35901626
pii: S1567-5394(22)00165-7
doi: 10.1016/j.bioelechem.2022.108214
pii:
doi:
Substances chimiques
Ions
0
Metals, Heavy
0
graphene oxide
0
Cadmium
00BH33GNGH
Lead
2P299V784P
Graphite
7782-42-5
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
108214Informations de copyright
Copyright © 2022. Published by Elsevier B.V.