Measurement of magnetostimulation thresholds in the porcine heart.
MRI gradient field switching
cardiac stimulation
electromagnetic exposure safety
magnetostimulation thresholds
Journal
Magnetic resonance in medicine
ISSN: 1522-2594
Titre abrégé: Magn Reson Med
Pays: United States
ID NLM: 8505245
Informations de publication
Date de publication:
11 2022
11 2022
Historique:
revised:
26
05
2022
received:
12
02
2022
accepted:
18
06
2022
pubmed:
31
7
2022
medline:
27
8
2022
entrez:
30
7
2022
Statut:
ppublish
Résumé
Powerful MRI gradient systems can surpass the International Electrotechnical Commission (IEC) 60601-2-33 limit for cardiac stimulation (CS), which was determined by simple electromagnetic simulations and electrode stimulation experiments. Only a few canine studies measured magnetically induced CS thresholds in vivo and extrapolating them to human safety limits can be challenging. We measured cardiac magnetostimulation thresholds in 10 healthy, anesthetized pigs using capacitors discharged into a flat spiral coil to produce damped sinusoidal waveforms with effective stimulus duration t The average dB/dt threshold estimated in the porcine heart was 1.66 ± 0.23 kT/s, which is 11-fold greater than the IEC dB/dt limit at t This first measurement of cardiac magnetostimulation thresholds in pigs indicates that the IEC cardiac safety limit is conservative for the investigated stimulus duration (t
Identifiants
pubmed: 35906903
doi: 10.1002/mrm.29382
pmc: PMC9420805
mid: NIHMS1817913
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
2242-2258Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL159010
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL131635
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL151704
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM008313
Pays : United States
Organisme : NIBIB NIH HHS
ID : R01 EB028250
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL135242
Pays : United States
Informations de copyright
© 2022 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.
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