Equine Gastric Squamous Cell Carcinoma in a Friesian Stallion.
Endoscopy
Horse
Neoplasia
Oesophageal stenosis
Stomach
Journal
Journal of equine veterinary science
ISSN: 0737-0806
Titre abrégé: J Equine Vet Sci
Pays: United States
ID NLM: 8216840
Informations de publication
Date de publication:
10 2022
10 2022
Historique:
received:
13
05
2022
revised:
14
07
2022
accepted:
25
07
2022
pubmed:
1
8
2022
medline:
20
9
2022
entrez:
31
7
2022
Statut:
ppublish
Résumé
A 7-year-old Friesian stallion with a history of oesophageal stenosis, weight loss, inappetence, and recurrent hyperthermia was referred for gastroscopy. The stomach mucosa surrounding the oesophageal opening showed a large, necrotic, and ulcerated mass. On post-mortem examination, a very large, cauliflower-like neoplasm was seen, affecting non-glandular gastric mucosa. Nodular lesions were observed, scattered on the omentum, the spleen, and the liver. Microscopic findings allowed the diagnosis of gastric squamous cell carcinoma with abdominal metastasis. Biomolecular investigations demonstrated the presence of EcPV-2 genes in neoplastic lesions, thus supporting the role of EcPV-2 in the ethiology of equine gastric cancer.
Identifiants
pubmed: 35908598
pii: S0737-0806(22)00223-4
doi: 10.1016/j.jevs.2022.104087
pii:
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
104087Informations de copyright
Copyright © 2022. Published by Elsevier Inc.
Déclaration de conflit d'intérêts
Conflict of Interest statement We declare that none of the authors (please, see the list below) has affiliation with any organization with a direct or indirect financial interest in the subject matter discussed in the manuscript. ▪ Paola Straticò ▪ Elisabetta Razzuoli ▪ Jasmine Hattab ▪ Giulia Guerri ▪ Gianluca Celani ▪ Adriana Palozzo ▪ Daniele Bonanni ▪ Floriana Fruscione ▪ Vincenzo Varasano ▪ Lucio Petrizzi ▪ Giuseppe Marruchella. Sincerely, Paola Straticò, PhD, DVM University of Teramo, Faculty of Veterinary Medicine Loc.. Piano D'Accio 64100 - Teramo (ITALY) pstratico@unite.it.