Association between gut microbiota and prediabetes in people living with HIV.
Gut microbiota
HIV
People living with HIV
Plasma glucose
Prediabetes
Journal
Current research in microbial sciences
ISSN: 2666-5174
Titre abrégé: Curr Res Microb Sci
Pays: Netherlands
ID NLM: 101773003
Informations de publication
Date de publication:
2022
2022
Historique:
received:
04
11
2021
revised:
27
05
2022
accepted:
30
05
2022
entrez:
1
8
2022
pubmed:
2
8
2022
medline:
2
8
2022
Statut:
epublish
Résumé
The prevalence of prediabetes is rapidly increasing in general population and in people living with HIV (PLWH). Gut microbiota play an important role in human health, and dysbiosis is associated with metabolic disorders and HIV infection. Here, we aimed to evaluate the association between gut microbiota and prediabetes in PLWH. A cross-sectional study enrolled 40 PLWH who were receiving antiretroviral therapy and had an undetectable plasma viral load. Twenty participants had prediabetes, and 20 were normoglycemic. Fecal samples were collected from all participants. The gut microbiome profiles were analyzed using 16S rRNA sequencing. Alpha-diversity was significantly lower in PLWH with prediabetes than in those with normoglycemia (
Identifiants
pubmed: 35909623
doi: 10.1016/j.crmicr.2022.100143
pii: S2666-5174(22)00040-2
pmc: PMC9325897
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100143Informations de copyright
© 2022 The Author(s).
Déclaration de conflit d'intérêts
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Références
Nat Commun. 2015 Apr 07;6:6498
pubmed: 25849138
Mol Ecol. 1993 Apr;2(2):113-8
pubmed: 8180733
BMJ. 2018 Jun 13;361:k2179
pubmed: 29899036
Sci Rep. 2018 Apr 30;8(1):6725
pubmed: 29712976
Front Immunol. 2020 Apr 09;11:645
pubmed: 32328074
AIDS Res Ther. 2020 May 24;17(1):25
pubmed: 32448349
Nat Med. 2017 Jan;23(1):107-113
pubmed: 27892954
Diabetologia. 2018 Apr;61(4):810-820
pubmed: 29379988
Nat Methods. 2016 Jul;13(7):581-3
pubmed: 27214047
BMJ Open. 2017 Mar 29;7(3):e013953
pubmed: 28360243
mSystems. 2018 Apr 17;3(3):
pubmed: 29719869
AIDS Res Ther. 2020 Mar 10;17(1):10
pubmed: 32156291
N Engl J Med. 1998 Mar 26;338(13):853-60
pubmed: 9516219
Front Microbiol. 2017 Sep 12;8:1749
pubmed: 28955319
PLoS One. 2021 May 13;16(5):e0251245
pubmed: 33983982
Front Microbiol. 2020 Feb 21;11:219
pubmed: 32153527
Nat Rev Microbiol. 2017 Oct;15(10):630-638
pubmed: 28626231
Sci Rep. 2015 Nov 13;5:16643
pubmed: 26563823
Neurology. 2003 Jan 14;60(1):108-11
pubmed: 12525727
Diabetologia. 2009 Aug;52(8):1511-9
pubmed: 19506831
Sci Rep. 2021 Jun 1;11(1):11494
pubmed: 34075098
Diabet Med. 2007 Feb;24(2):137-44
pubmed: 17257275
Benef Microbes. 2017 Aug 24;8(4):545-556
pubmed: 28701081
Curr Protein Pept Sci. 2019;20(2):145-154
pubmed: 29756574
Sci Rep. 2020 Mar 25;10(1):5450
pubmed: 32214153
Nat Rev Nephrol. 2019 Jul;15(7):389-390
pubmed: 30918350
Viruses. 2021 Sep 22;13(10):
pubmed: 34696320
Open Forum Infect Dis. 2020 Sep 11;7(9):ofaa338
pubmed: 32964062
Microbiome. 2018 Sep 24;6(1):172
pubmed: 30249275
Eur Cardiol. 2019 Apr;14(1):50-59
pubmed: 31131037
J Clin Endocrinol Metab. 2016 Apr;101(4):1445-54
pubmed: 26938201
Clin J Am Soc Nephrol. 2010 Apr;5(4):673-82
pubmed: 20338960
Diabetes Care. 2006 Jan;29(1):26-31
pubmed: 16373891
Cell. 2014 Nov 6;159(4):789-99
pubmed: 25417156
Nucleic Acids Res. 2013 Jan;41(Database issue):D590-6
pubmed: 23193283
Microbiome. 2018 Apr 25;6(1):77
pubmed: 29695307
Arch Intern Med. 2005 May 23;165(10):1179-84
pubmed: 15911733
Front Microbiol. 2018 Feb 21;9:151
pubmed: 29515527
Nature. 2012 Sep 13;489(7415):220-30
pubmed: 22972295
EBioMedicine. 2018 Nov;37:392-400
pubmed: 30366816
Cell Metab. 2020 Sep 1;32(3):379-390.e3
pubmed: 32652044
Diabetes Care. 2011 Sep;34(9):1980-5
pubmed: 21816976
mSystems. 2020 Mar 31;5(2):
pubmed: 32234773
BMC Biol. 2019 Oct 28;17(1):83
pubmed: 31660948
Microb Pathog. 2017 May;106:171-181
pubmed: 26875998
J Diabetes Obes. 2015 Dec 26;2(3):1-7
pubmed: 26756039
Nat Microbiol. 2021 May;6(5):563-573
pubmed: 33820962
Appl Environ Microbiol. 2005 Dec;71(12):8228-35
pubmed: 16332807
Diabetes Metab Syndr Obes. 2021 May 17;14:2177-2188
pubmed: 34040404
Microbiome. 2018 May 17;6(1):90
pubmed: 29773078
Lancet. 2012 Jun 16;379(9833):2279-90
pubmed: 22683128
J Anim Sci Biotechnol. 2021 May 6;12(1):61
pubmed: 33952344
Diabetes Care. 2019 Jan;42(Suppl 1):S13-S28
pubmed: 30559228
Microb Pathog. 2017 Oct;111:362-369
pubmed: 28912092
Lipids Health Dis. 2018 Jan 22;17(1):17
pubmed: 29357881
Appl Environ Microbiol. 2007 Mar;73(5):1576-85
pubmed: 17220268
PLoS One. 2010 Feb 05;5(2):e9085
pubmed: 20140211
J Int Assoc Physicians AIDS Care (Chic). 2010 Nov-Dec;9(6):358-61
pubmed: 21075913
Nat Biotechnol. 2019 Aug;37(8):852-857
pubmed: 31341288
Nutrients. 2018 May 08;10(5):
pubmed: 29738477