Vitamin D Supplementation: Association With Serum Cytokines in Pediatric Hematopoietic Stem Cell Transplantation.
cytokine-immunological terms
hematopoietic cell transplantation
pediatric
transplant complications
vitamin D
Journal
Frontiers in pediatrics
ISSN: 2296-2360
Titre abrégé: Front Pediatr
Pays: Switzerland
ID NLM: 101615492
Informations de publication
Date de publication:
2022
2022
Historique:
received:
05
04
2022
accepted:
20
06
2022
entrez:
1
8
2022
pubmed:
2
8
2022
medline:
2
8
2022
Statut:
epublish
Résumé
Vitamin D deficiency is prevalent in pediatric patients presenting for hematopoietic stem cell transplantation (HSCT) and has been linked to poor clinical outcomes. Using the data from a randomized control trial, in this paper we explore the effects of vitamin D supplementation on circulating cytokine levels during pediatric HSCT (www.clinicaltrials.gov as NCT03176849). A total of 41 children, 20 received Stoss therapy and 21 children received standard of care vitamin D supplementation. Levels of 25(OH)D and 20 cytokines were assessed at baseline and day +30. Significantly (
Identifiants
pubmed: 35911824
doi: 10.3389/fped.2022.913586
pmc: PMC9326107
doi:
Banques de données
ClinicalTrials.gov
['NCT03176849']
Types de publication
Journal Article
Langues
eng
Pagination
913586Subventions
Organisme : NCATS NIH HHS
ID : KL2 TR001429
Pays : United States
Informations de copyright
Copyright © 2022 Olsen, Bodea, Garcia, Beebe, Campbell, Schwalbach, Salzberg, Miller, Adams, Mirea, Castillo, Horn, Bansal, Mohanakumar and Ngwube.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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