Long COVID headache.


Journal

The journal of headache and pain
ISSN: 1129-2377
Titre abrégé: J Headache Pain
Pays: England
ID NLM: 100940562

Informations de publication

Date de publication:
01 Aug 2022
Historique:
received: 28 05 2022
accepted: 28 06 2022
entrez: 1 8 2022
pubmed: 2 8 2022
medline: 4 8 2022
Statut: epublish

Résumé

Headache is among the most frequent symptoms persisting or newly developing after coronavirus disease 2019 (COVID-19) as part of the so-called long COVID syndrome. The knowledge on long COVID headache is still limited, however growing evidence is defining the features of this novel condition, in particular regarding clinical characteristics, some pathophysiological mechanisms and first treatment recommendations. Long COVID headache can present in the form of worsening of a preexisting primary headache, or, more specifically, in the form of a new (intermittent or daily) headache starting during the acute infection or after a delay. It often presents together with other long COVID symptoms, most frequently with hyposmia. It can manifest with a migrainous or, more frequently, with a tension-type-like phenotype. Persistent activation of the immune system and trigeminovascular activation are thought to play a role. As there are virtually no treatment studies, treatment currently is largely guided by the existing guidelines for primary headaches with the corresponding phenotype. The present report, a collaborative work of the international group of the Junior Editorial Board of The Journal of Headache and Pain aims to summarize the most recent evidence about long COVID headache and suggests approaches to the diagnosis and treatment of this disorder.

Identifiants

pubmed: 35915417
doi: 10.1186/s10194-022-01450-8
pii: 10.1186/s10194-022-01450-8
pmc: PMC9340759
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

93

Informations de copyright

© 2022. The Author(s).

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Auteurs

Claudio Tana (C)

Center of Excellence On Headache, Geriatrics and COVID-19 Clinic, SS Annunziata Hospital of Chieti, 66100, Chieti, Italy. claudio.tana@asl2abruzzo.it.

Enrico Bentivegna (E)

Internal Medicine and Emergency Medicine, Sant' Andrea Hospital, Sapienza University, Rome, Italy.

Soo-Jin Cho (SJ)

Department of Neurology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Republic of Korea.

Andrea M Harriott (AM)

Headache and Neuropathic Pain Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

David García-Azorín (D)

Headache Unit, Department of Neurology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.

Alejandro Labastida-Ramirez (A)

Headache Group, Wolfson Center for Age Related Diseases, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Raffaele Ornello (R)

Departement of Applied Clinical Sciences and Biotechnology, University of L'Aquila, L'Aquila, Italy.

Bianca Raffaelli (B)

Department of Neurology, Charité Universitätsmedizin Berlin, Berlin, Germany.

Eloísa Rubio Beltrán (ER)

Headache Group, Wolfson Center for Age Related Diseases, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Ruth Ruscheweyh (R)

Department of Neurology, Ludwig Maximilians University, Munich, Germany.
German Migraine and Headache Society, Frankfurt, Germany.
Department of Psychosomatic Medicine and Psychotherapy, Technical University of Munich, Munich, Germany.

Paolo Martelletti (P)

Internal Medicine and Emergency Medicine, Sant' Andrea Hospital, Sapienza University, Rome, Italy.

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