Association Between Dialysis Facility Ownership and Access to the Waiting List and Transplant in Pediatric Patients With End-stage Kidney Disease in the US.


Journal

JAMA
ISSN: 1538-3598
Titre abrégé: JAMA
Pays: United States
ID NLM: 7501160

Informations de publication

Date de publication:
02 08 2022
Historique:
entrez: 2 8 2022
pubmed: 3 8 2022
medline: 5 8 2022
Statut: ppublish

Résumé

Care of adults at profit vs nonprofit dialysis facilities has been associated with lower access to transplant. Whether profit status is associated with transplant access for pediatric patients with end-stage kidney disease is unknown. To determine whether profit status of dialysis facilities is associated with placement on the kidney transplant waiting list or receipt of kidney transplant among pediatric patients receiving maintenance dialysis. This retrospective cohort study reviewed the US Renal Data System records of 13 333 patients younger than 18 years who started dialysis from 2000 through 2018 in US dialysis facilities (followed up through June 30, 2019). Time-updated profit status of dialysis facilities. Cox models, adjusted for clinical and demographic factors, were used to examine time to wait-listing and receipt of kidney transplant by profit status of dialysis facilities. A total of 13 333 pediatric patients who started receiving maintenance dialysis were included in the analysis (median age, 12 years [IQR, 3-15 years]; 6054 females [45%]; 3321 non-Hispanic Black patients [25%]; 3695 Hispanic patients [28%]). During a median follow-up of 0.87 years (IQR, 0.39-1.85 years), the incidence of wait-listing was lower at profit facilities than at nonprofit facilities, 36.2 vs 49.8 per 100 person-years, respectively (absolute risk difference, -13.6 (95% CI, -15.4 to -11.8 per 100 person-years; adjusted hazard ratio [HR] for wait-listing at profit vs nonprofit facilities, 0.79; 95% CI, 0.75-0.83). During a median follow-up of 1.52 years (IQR, 0.75-2.87 years), the incidence of kidney transplant (living or deceased donor) was also lower at profit facilities than at nonprofit facilities, 21.5 vs 31.3 per 100 person-years, respectively; absolute risk difference, -9.8 (95% CI, -10.9 to -8.6 per 100 person-years) adjusted HR for kidney transplant at profit vs nonprofit facilities, 0.71 (95% CI, 0.67-0.74). Among a cohort of pediatric patients receiving dialysis in the US from 2000 through 2018, profit facility status was associated with longer time to wait-listing and longer time to kidney transplant.

Identifiants

pubmed: 35916847
pii: 2794764
doi: 10.1001/jama.2022.11231
pmc: PMC9346544
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

451-459

Subventions

Organisme : NIDDK NIH HHS
ID : R01 DK120886
Pays : United States

Commentaires et corrections

Type : CommentIn
Type : CommentIn

Références

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Auteurs

Sandra Amaral (S)

Children's Hospital of Philadelphia, Division of Pediatric Nephrology, Department of Pediatrics, Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

Charles E McCulloch (CE)

Department of Epidemiology and Biostatistics, University of California, San Francisco.

Feng Lin (F)

Department of Epidemiology and Biostatistics, University of California, San Francisco.

Barbara A Grimes (BA)

Department of Epidemiology and Biostatistics, University of California, San Francisco.

Susan Furth (S)

Children's Hospital of Philadelphia, Division of Pediatric Nephrology, Department of Pediatrics, Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

Bradley Warady (B)

Division of Pediatric Nephrology, Department of Pediatrics, Children's Mercy Kansas City, Kansas City, Missouri.

Celina Brunson (C)

Division of Pediatric Nephrology, Children's National Health System, The George Washington University School of Medicine and Health Sciences, Washington, DC.

Salpi Siyahian (S)

Division of Nephrology, Department of Medicine and Pediatrics, University of California, San Francisco.

Elaine Ku (E)

Department of Epidemiology and Biostatistics, University of California, San Francisco.
Division of Nephrology, Department of Medicine and Pediatrics, University of California, San Francisco.

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