Development of an Anti-human CCR2 Monoclonal Antibody (C

Animals Antibodies, Monoclonal Immunization Mice Peptides Receptors, CCR2
CCR2 flow cytometry monoclonal antibody

Journal

Monoclonal antibodies in immunodiagnosis and immunotherapy
ISSN: 2167-9436
Titre abrégé: Monoclon Antib Immunodiagn Immunother
Pays: United States
ID NLM: 101590955

Informations de publication

Date de publication:
Aug 2022
Historique:
pubmed: 3 8 2022
medline: 31 8 2022
entrez: 2 8 2022
Statut: ppublish

Résumé

The CC chemokine receptor type-2 (CCR2) is one of the members of the G protein-coupled receptor superfamily, which are expressed on the cell surface of immune and tumor cells. CCR2 binds to the C-C motif chemokine ligand 2 (CCL2)/monocyte chemoattractant protein-1 (MCP-1), which is produced by various cells, including tumor and immune-related cells. Therefore, the development of sensitive monoclonal antibodies (mAbs) for CCR2 has been desired for treatment and diagnosis. In this study, we established a specific antihuman CCR2 (hCCR2) mAb, C

Identifiants

DOI: 10.1089/mab.2022.0001 PMID: 35917563
pubmed: 35917563
doi: 10.1089/mab.2022.0001
doi:

Substances chimiques

Antibodies, Monoclonal 0
Ccr2 protein, mouse 0
Peptides 0
Receptors, CCR2 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

188-193

Auteurs

Tomohiro Tanaka (T)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Guanjie Li (G)

Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Masaki Saito (M)

Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Hiroyuki Suzuki (H)

Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Teizo Asano (T)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Mika K Kaneko (MK)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Yukinari Kato (Y)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.
Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.
ORCID: 0000-0001-5385-8201

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Development of an Anti-human CCR2 Monoclonal...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Anticorps monoclonaux › Development of an Anti-human CCR2 Monoclonal...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pratiques en santé publique › Prévention primaire › Immunisation › Development of an Anti-human CCR2 Monoclonal...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Development of an Anti-human CCR2 Monoclonal...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Development of an Anti-human CCR2 Monoclonal...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Récepteurs aux cytokines › Récepteurs aux chimiokines › Récepteurs CCR › Récepteurs CCR2 › Development of an Anti-human CCR2 Monoclonal...