Risk of depression after coronary artery bypass grafting: a SWEDEHEART population-based cohort study.
Coronary artery bypass grafting
Depression
Survival
Journal
European heart journal open
ISSN: 2752-4191
Titre abrégé: Eur Heart J Open
Pays: England
ID NLM: 9918282081406676
Informations de publication
Date de publication:
Mar 2022
Mar 2022
Historique:
received:
01
12
2021
revised:
10
02
2022
accepted:
01
03
2022
entrez:
3
8
2022
pubmed:
4
8
2022
medline:
4
8
2022
Statut:
epublish
Résumé
A diagnosis of depression in patients with coronary heart disease is associated with worse outcomes. This study examined the long-term risk for new onset of depression after coronary artery bypass grafting (CABG) compared to an age- and sex-matched control group from the general population. In total, 125 418 primary isolated CABG patients and 495 371 matched controls were included from 1992 to 2017. The SWEDEHEART registry and three other national registers were used to acquire information about baseline characteristics and depression. The adjusted risk of depression was estimated by using Cox regression models adjusted for patient characteristics, and socioeconomic variables, described by hazard ratios (HR) and 95% confidence intervals (CI). In total, 6202 (4.9%) CABG patients and 17 854 (3.6%) controls developed depression. The cumulative incidence of depression was higher in CABG patients than in the control population [6.1%, 95% CI 6.0-6.3 vs. 4.7% (4.7-4.8), Patients who underwent CABG had a higher risk of new onset of depression compared to sex- and age-matched controls in the general population. The risk of depression was especially pronounced in younger patients during the first 5 years after surgery.
Identifiants
pubmed: 35919122
doi: 10.1093/ehjopen/oeac015
pii: oeac015
pmc: PMC9242047
doi:
Types de publication
Journal Article
Langues
eng
Pagination
oeac015Informations de copyright
© The Author(s) 2022. Published by Oxford University Press on behalf of the European Society of Cardiology.
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