Clinico-laboratory findings of Malassezia folliculitis in Indonesia: A multicentre study.
KOH
Malassezia folliculitis
modified Jacinta-Jamora criteria
papulopustular
pruritus
trunk
Journal
Mycoses
ISSN: 1439-0507
Titre abrégé: Mycoses
Pays: Germany
ID NLM: 8805008
Informations de publication
Date de publication:
Oct 2022
Oct 2022
Historique:
revised:
15
07
2022
received:
29
05
2022
accepted:
26
07
2022
pubmed:
4
8
2022
medline:
20
9
2022
entrez:
3
8
2022
Statut:
ppublish
Résumé
Malassezia folliculitis (MF) is a humid-favoured fungal skin disease caused by Malassezia species. Inaccurate treatments, changes in skin flora and disease exacerbation are often occurred due to oversights in the diagnosis. Several diagnostic methods are established for MF. To identify clinico-laboratory findings of Malassezia folliculitis in Indonesia. The study was conducted from January 2014 to December 2018 in seven referral teaching hospitals. Medical records of MF-diagnosed patients were obtained and analysed using the binomial test, chi-square test and Cohen's Kappa coefficient in SPSS 26.0. A total of 353 cases of MF were identified in seven referral teaching hospitals in Indonesia, 66.3% of which were males and 33.7% were females, dominated by the 17-25 years old group (44.5%). Itchy sensation (83.9%) was a major subjective complaint. Lesions were majorly found on the trunk-chest, back and shoulder (68.3%), while the clinical manifestation are mostly follicular papule-pustular lesions (62.1%). Patients were 87.4% positive by KOH examination (modified Jacinto Jamora's criteria) and 69.1% positive by Wood's lamp. Generally, sex, age, subjective complaint, lesion location, clinical manifestation and both examinations were statistically significant (p < .001). A significant relationship between all the clinical criteria of the patients in the KOH especially the clinical manifestation was significantly related to Wood's lamp. The Cohen's Kappa assessment suggested that there was an agreement between KOH and Wood's lamp (κ = -0.272, p < .001). The clinical symptoms of Malassezia folliculitis are dominated by pruritus, papulopustular follicular lesions on the trunk and the presence of spore load.
Sections du résumé
BACKGROUND
BACKGROUND
Malassezia folliculitis (MF) is a humid-favoured fungal skin disease caused by Malassezia species. Inaccurate treatments, changes in skin flora and disease exacerbation are often occurred due to oversights in the diagnosis. Several diagnostic methods are established for MF.
OBJECTIVE
OBJECTIVE
To identify clinico-laboratory findings of Malassezia folliculitis in Indonesia.
METHODS
METHODS
The study was conducted from January 2014 to December 2018 in seven referral teaching hospitals. Medical records of MF-diagnosed patients were obtained and analysed using the binomial test, chi-square test and Cohen's Kappa coefficient in SPSS 26.0.
RESULTS
RESULTS
A total of 353 cases of MF were identified in seven referral teaching hospitals in Indonesia, 66.3% of which were males and 33.7% were females, dominated by the 17-25 years old group (44.5%). Itchy sensation (83.9%) was a major subjective complaint. Lesions were majorly found on the trunk-chest, back and shoulder (68.3%), while the clinical manifestation are mostly follicular papule-pustular lesions (62.1%). Patients were 87.4% positive by KOH examination (modified Jacinto Jamora's criteria) and 69.1% positive by Wood's lamp. Generally, sex, age, subjective complaint, lesion location, clinical manifestation and both examinations were statistically significant (p < .001). A significant relationship between all the clinical criteria of the patients in the KOH especially the clinical manifestation was significantly related to Wood's lamp. The Cohen's Kappa assessment suggested that there was an agreement between KOH and Wood's lamp (κ = -0.272, p < .001).
CONCLUSION
CONCLUSIONS
The clinical symptoms of Malassezia folliculitis are dominated by pruritus, papulopustular follicular lesions on the trunk and the presence of spore load.
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
953-959Informations de copyright
© 2022 Wiley-VCH GmbH.
Références
Ogba O, Idoo-Bube B. Malassezia infections: Diagnostic perspective and treatment approach in Africa. IOSR Journal Of Pharmacy And Biological Sciences (IOSR-JPBS). 2019;14:37-43. https://doi.org/10.9790/3008-1401033743
Saunte DM, Gaitanis G, Hay RJ. Malassezia-associated skin diseases, the use of diagnostics and treatment. Front Cell Infect Microbiol. 2020;10(112):1-11. https://doi.org/10.3389/fcimb.2020.00112
Ahronowitz I, Leslie K. Yeast infections. Fitzpatrick's dermatology. 9th ed. McGraw Hill; 2019:2953-2964.
Levin NA, Delano S. Malassezia-related skin diSoRdeRS [Internet]. 2011;24(3):137-145. https://www.mdedge.com/dermatology/article/69945/pigmentation-disorders/evaluation-and-treatment-malassezia-related-skin
Hald M, Arendrup MC, Svejgaard EL, Lindskov R, Foged EK, Saunte DML. Evidence-based Danish guidelines for the treatment of malassezia related skin diseases. Acta Derm Venereol. 2015;95(1):12-19.
Bahlou E, Abderrahmen M, Fatma F, et al. Malassezia folliculitis: prevalence, clinical features risk factors and treatment: a prospective randomized comparative study [Internet]. J Immunol Microbiol. 2018;2(1):1-5. http://www.imedpub.com/
Jacinto-Jamora S, Tamesis J, Katigbak ML. Pityrosporum folliculitis in The Philippines: diagnosis, prevalence, and management. J Am Acad Dermatol. 1991;24(5):693-696.
Bulmer GS, Pu XM, Yi LXT. Malassezia folliculitis in China. Mycopathologia. 2008;165(6):411-412.
Mei-Yen Yong A, Tan SY, Tan CL. An update on pityrosporum folliculitis in Singapore from a single tertiary care dermatological centre. Singapore Med J. 2021;62(10):526-528.
Rubenstein RM, Malerich SA. Malassezia (Pityrosporum) folliculitis. J Clin Aesthet Dermatol. 2014;7:37-41.
Sharquie KE, Al-Hamdi KI, Al-Haroon SS, Al-Mohammadi A. Malassezia folliculitis versus truncal acne vulgaris (clinical and histopathological study). J Cosmet Dermatol Sci Appl. 2012;02(4):277-282.
Durdu M, Eskiocak AH. The role of diagnostic approaches to determine the treatment. Turk J Dermatol. 2018;12:120-128.
Jakhar D, Bhatia V, Gupta RK, Kaur I. Dermoscopy as an auxiliary tool in the assessment of Malassezia folliculitis: an observational study. Actas Dermo-Sifiliograficas. 2022;113(1):78-81. https://doi.org/10.1016/j.ad.2020.05.012
Tsai YC, Wang J-Y, Wu Y-H, Wang Y-J. Clinical differences in pediatric and adult Malassezia folliculitis: retrospective analysis of 321 cases over 9 years. J Am Acad Dermatol. 2019;81:278-280.
Widaty S, Miranda E, Menaldi SL, et al. Prognostic factors impacting clinical outcome following Malassezia folliculitis treatment. Iran J. 2022.
Suling PL, Niode NJ, Sondakh Reymond Octavia. 23rd Regional Conference of Dermatology. Prognostic cure rate of Malassezia folliculitis in Indonesia. Proceeding Book; 2018.
Thayikkannu AB, Kindo JA, Veeraraghavan V. Malassezia-Can it be ignored? Indian J Dermatol. 2015;60:332-339.
Malgotra V, Singh H. Malassezia (Pityrosporum) folliculitis masquerading as recalcitrant acne. Cureus. 2021;13:e13534.
Reiss E, Shadomy HJ, Lyon GM. Fundamental medical mycology. John Wiley & Sons; 2011:582.
Remya VS, Arun B. Diagnostic efficacy of Wood's lamp examination compared with KOH wet mount for diagnosis of pityriasis versicolor cases 2019. Int J Health Sci Res. 2019;9(4). https://www.ijhsr.org/IJHSR_Vol.9_Issue.4_April2019/IJHSR_Abstract.05.html
al Aboud DM, Gossman W. Wood's light. StatPearls Publishing; 2022:1-7.