Circulating short-chain fatty acids in type 2 diabetic patients and overweight/obese individuals.
Gut microbiota
Obesity
Short-chain fatty acids
Type 2 diabetes
Journal
Acta diabetologica
ISSN: 1432-5233
Titre abrégé: Acta Diabetol
Pays: Germany
ID NLM: 9200299
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
received:
02
05
2022
accepted:
30
06
2022
pubmed:
4
8
2022
medline:
22
10
2022
entrez:
3
8
2022
Statut:
ppublish
Résumé
aim of the study was to evaluate serum short chain fatty acids (SCFA) concentrations in patients with Type 2 diabetes (T2D) and overweight/obese individuals. In forty-three patients with T2D and twenty-eight overweight/obese patients SCFA were determined by Gas-Chromatography/Flame Ionization Detector (GC/FID). Acetic acid, propionic acid, butyric acid, and total SCFA were significantly reduced in T2D patients compared to overweight/obese in the unadjusted model. Adjusting for all variables only propionic acid remained significantly lower in T2D. Only reduction of propionic acid was closely related to diabetes itself, regardless of all other factors.
Identifiants
pubmed: 35920899
doi: 10.1007/s00592-022-01934-8
pii: 10.1007/s00592-022-01934-8
doi:
Substances chimiques
propionic acid
JHU490RVYR
Propionates
0
Fatty Acids, Volatile
0
Butyric Acid
107-92-6
Acetic Acid
Q40Q9N063P
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1653-1656Informations de copyright
© 2022. Springer-Verlag Italia S.r.l., part of Springer Nature.
Références
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