The m
Hippo/YAP
LATS2
N6-methyladenosine (m(6)A)
hepatic stellate cells (HSCs)
liver fibrosis
Journal
Molecular therapy : the journal of the American Society of Gene Therapy
ISSN: 1525-0024
Titre abrégé: Mol Ther
Pays: United States
ID NLM: 100890581
Informations de publication
Date de publication:
07 12 2022
07 12 2022
Historique:
received:
17
03
2022
revised:
21
06
2022
accepted:
30
07
2022
pubmed:
5
8
2022
medline:
15
12
2022
entrez:
4
8
2022
Statut:
ppublish
Résumé
Activation of hepatic stellate cells (HSCs) is a central driver of liver fibrosis. Previous investigations have identified various altered epigenetic landscapes during the cellular progression of HSC activation. N6-methyladenosine (m
Identifiants
pubmed: 35923112
pii: S1525-0016(22)00441-5
doi: 10.1016/j.ymthe.2022.07.020
pmc: PMC9734030
pii:
doi:
Substances chimiques
Methyltransferases
EC 2.1.1.-
Protein Serine-Threonine Kinases
EC 2.7.11.1
Tumor Suppressor Proteins
0
Mettl3 protein, mouse
EC 2.1.1.-
LATS2 protein, mouse
EC 2.7.11.1
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
3714-3728Informations de copyright
Copyright © 2022 The American Society of Gene and Cell Therapy. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of interests The authors have declared that no conflict of interest exists.
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