Major cardiac surgery with recombinant FIX Fc fusion protein replacement in hemophilia B: a case report.
Bentall’s operation
case report
eftrenonacog alfa
Journal
Therapeutic advances in hematology
ISSN: 2040-6207
Titre abrégé: Ther Adv Hematol
Pays: England
ID NLM: 101549589
Informations de publication
Date de publication:
2022
2022
Historique:
received:
13
01
2022
accepted:
16
05
2022
entrez:
4
8
2022
pubmed:
5
8
2022
medline:
5
8
2022
Statut:
epublish
Résumé
The introduction of extended factor IX (FIX) products has significantly facilitated the treatment of hemophilia B patients. However, optimal perioperative management remains a topic of hot debate, particularly in surgeries with high bleeding risk. For the first time, we report here a patient with mild hemophilia B and degenerative aneurysms of aortic root and ascending aorta undergoing elective Bentall's operation with full cardiopulmonary bypass, who was successfully managed with eftrenonacog alfa (Alprolix
Identifiants
pubmed: 35923771
doi: 10.1177/20406207221104595
pii: 10.1177_20406207221104595
pmc: PMC9340359
doi:
Types de publication
Case Reports
Langues
eng
Pagination
20406207221104595Informations de copyright
© The Author(s), 2022.
Déclaration de conflit d'intérêts
Competing interests: The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: CF reports research grant, reimbursement for attending symposium, and consulting fees from Sobi. The remaining authors declare that they have no conflict of interest.
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