Personality traits as mediators of the relationship between childhood trauma and depression severity in bipolar disorder: A structural equation model.


Journal

The Australian and New Zealand journal of psychiatry
ISSN: 1440-1614
Titre abrégé: Aust N Z J Psychiatry
Pays: England
ID NLM: 0111052

Informations de publication

Date de publication:
Jul 2023
Historique:
medline: 26 6 2023
pubmed: 5 8 2022
entrez: 4 8 2022
Statut: ppublish

Résumé

Childhood trauma is negatively associated with depression severity in bipolar disorder; however, the underlying mechanisms remain unclear. We investigated whether personality traits (neuroticism, extraversion, openness, agreeableness, conscientiousness) mediate the relationship between childhood trauma and the severity of bipolar depression. Data from 209 individuals with bipolar disorder recruited for the Prechter Longitudinal Study of Bipolar Disorder were analysed. Using structural equation modelling, we examined the direct and indirect associations between childhood trauma (Childhood Trauma Questionnaire) and depression severity (Hamilton Depression Rating Scale) - with the personality traits (NEO Personality Inventory-Revised) as mediators. The direct effect of childhood trauma on depression severity (standardised β = 0.32, 95% bootstrap confidence interval [CI] = 0.20-0.45, Personality traits may be relevant psychological mediators that link childhood trauma to a more severe clinical presentation of bipolar depression. Consequently, a person's personality structure may be a crucial operative factor to incorporate in therapeutic plans when treating individuals with bipolar disorder who report a history of childhood trauma.

Sections du résumé

BACKGROUND UNASSIGNED
Childhood trauma is negatively associated with depression severity in bipolar disorder; however, the underlying mechanisms remain unclear. We investigated whether personality traits (neuroticism, extraversion, openness, agreeableness, conscientiousness) mediate the relationship between childhood trauma and the severity of bipolar depression.
METHODS UNASSIGNED
Data from 209 individuals with bipolar disorder recruited for the Prechter Longitudinal Study of Bipolar Disorder were analysed. Using structural equation modelling, we examined the direct and indirect associations between childhood trauma (Childhood Trauma Questionnaire) and depression severity (Hamilton Depression Rating Scale) - with the personality traits (NEO Personality Inventory-Revised) as mediators.
RESULTS UNASSIGNED
The direct effect of childhood trauma on depression severity (standardised β = 0.32, 95% bootstrap confidence interval [CI] = 0.20-0.45,
CONCLUSION UNASSIGNED
Personality traits may be relevant psychological mediators that link childhood trauma to a more severe clinical presentation of bipolar depression. Consequently, a person's personality structure may be a crucial operative factor to incorporate in therapeutic plans when treating individuals with bipolar disorder who report a history of childhood trauma.

Identifiants

pubmed: 35924739
doi: 10.1177/00048674221115644
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1031-1042

Subventions

Organisme : NIMH NIH HHS
ID : K23 MH109762
Pays : United States

Auteurs

Anna L Wrobel (AL)

Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, VIC, Australia.
Orygen, Parkville, VIC, Australia.

Samantha E Russell (SE)

Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, VIC, Australia.

Anuradhi Jayasinghe (A)

Orygen, Parkville, VIC, Australia.
School of Psychology, Deakin University, Geelong, VIC, Australia.

Bianca E Kavanagh (BE)

Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, VIC, Australia.

Mojtaba Lotfaliany (M)

Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, VIC, Australia.

Alyna Turner (A)

Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, VIC, Australia.
School of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia.

Olivia M Dean (OM)

Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, VIC, Australia.
Florey Institute for Neuroscience and Mental Health, The University of Melbourne, Melbourne, VIC, Australia.

Sue M Cotton (SM)

Orygen, Parkville, VIC, Australia.
Centre for Youth Mental Health, The University of Melbourne, Parkville, VIC, Australia.

Claudia Diaz-Byrd (C)

Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA.

Anastasia K Yocum (AK)

Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA.

Elizabeth R Duval (ER)

Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA.

Tobin J Ehrlich (TJ)

Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA.

David F Marshall (DF)

Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA.

Michael Berk (M)

Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, VIC, Australia.
Orygen, Parkville, VIC, Australia.
Florey Institute for Neuroscience and Mental Health, The University of Melbourne, Melbourne, VIC, Australia.
Centre for Youth Mental Health, The University of Melbourne, Parkville, VIC, Australia.
Department of Psychiatry, Royal Melbourne Hospital, The University of Melbourne, Parkville, VIC, Australia.

Melvin G McInnis (MG)

Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA.

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