Outcomes of biologic versus synthetic mesh in CDC class 3 and 4 open abdominal wall reconstruction.
Abdominal wall reconstruction
Biologic mesh
Contaminated
Hernia
Mesh choice
Ventral hernia repair
Journal
Surgical endoscopy
ISSN: 1432-2218
Titre abrégé: Surg Endosc
Pays: Germany
ID NLM: 8806653
Informations de publication
Date de publication:
04 2023
04 2023
Historique:
received:
29
03
2022
accepted:
13
07
2022
medline:
11
4
2023
pubmed:
5
8
2022
entrez:
4
8
2022
Statut:
ppublish
Résumé
Abdominal wall reconstruction (AWR) in a contaminated field is associated with an increased risk of wound complications, infection, and reoperation. The best method of repair and mesh choice in these operations have generated marked controversy. Our aim was to compare outcomes of patients who underwent AWR with biologic versus synthetic mesh in CDC class 3 and 4 wounds. A prospective, single-institution database was queried for AWR using biologic or synthetic mesh in CDC Class 3 and 4 wounds. Hernia recurrence and complications were measured. Multivariable logistic regression was performed to identify factors predicting both. In total, 386 patients with contaminated wounds underwent AWR, 335 with biologic and 51 with synthetic mesh. Groups were similar in age, sex, BMI, and rate of diabetes. Biologic mesh patients had larger hernia defects (298 ± 233cm Wound complications in AWR with CDC class 3 and 4 wounds significantly increased mesh infection and hernia recurrence; failure to achieve fascial closure also increased hernia recurrence. Use of synthetic versus biologic mesh increased the mesh infection rate by 18.6 times.
Identifiants
pubmed: 35925400
doi: 10.1007/s00464-022-09486-2
pii: 10.1007/s00464-022-09486-2
doi:
Substances chimiques
Biological Products
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
3073-3083Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Références
Kao AM, Arnold MR, Augenstein VA, Heniford BT (2018) Prevention and treatment strategies for mesh infection in abdominal wall reconstruction. Plast Reconstr Surg 142(3S):149S-155S. https://doi.org/10.1097/PRS.0000000000004871
doi: 10.1097/PRS.0000000000004871
pubmed: 30138283
Heniford BT, Ross SW, Wormer BA et al (2020) Preperitoneal ventral hernia repair: a decade long prospective observational study with analysis of 1023 patient outcomes. Ann Surg 271(2):364–374. https://doi.org/10.1097/SLA.0000000000002966
doi: 10.1097/SLA.0000000000002966
pubmed: 30080725
Augenstein VA, Colavita PD, Wormer BA et al (2015) CeDAR: Carolinas Equation for Determining Associated Risks. J Am Coll Surg 221(4):S65–S66. https://doi.org/10.1016/J.JAMCOLLSURG.2015.07.145
doi: 10.1016/J.JAMCOLLSURG.2015.07.145
Rosen MJ, Bauer JJ, Harmaty M et al (2017) Multicenter, prospective, longitudinal study of the recurrence, surgical site infection, and quality of life after contaminated ventral hernia repair using biosynthetic absorbable mesh: the COBRA study. Ann Surg 265(1):205–211. https://doi.org/10.1097/SLA.0000000000001601
doi: 10.1097/SLA.0000000000001601
pubmed: 28009747
Urbach DR, Horvath KD, Baxter NN et al (2007) A research agenda for gastrointestinal and endoscopic surgery. Surg Endosc Other Interv Tech 21(9):1518–1525. https://doi.org/10.1007/s00464-006-9141-4
doi: 10.1007/s00464-006-9141-4
Cevasco M, Itani KMF (2012) Ventral hernia repair with synthetic, composite, and biologic mesh: characteristics, indications, and infection profile. Surg Infect 13(4):209–215. https://doi.org/10.1089/SUR.2012.123
doi: 10.1089/SUR.2012.123
Burns NK, Jaffari MV, Rios CN, Mathur AB, Butler CE (2010) Non-cross-linked porcine acellular dermal matrices for abdominal wall reconstruction. Plastic Reconst Surg 125(1):167–176. https://doi.org/10.1097/PRS.0B013E3181C2A6ED
doi: 10.1097/PRS.0B013E3181C2A6ED
Shankaran V, Weber DJ, Reed RL, Luchette FA (2011) A review of available prosthetics for ventral hernia repair. Ann Surg 253(1):16–26. https://doi.org/10.1097/SLA.0b013e3181f9b6e6
doi: 10.1097/SLA.0b013e3181f9b6e6
pubmed: 21135699
Köckerling F, Alam NN, Antoniou SA et al (2018) What is the evidence for the use of biologic or biosynthetic meshes in abdominal wall reconstruction? Hernia 22(2):249–269. https://doi.org/10.1007/S10029-018-1735-Y
doi: 10.1007/S10029-018-1735-Y
pubmed: 29388080
pmcid: 5978919
Huntington CR, Cox TC, Blair LJ et al (2016) Biologic mesh in ventral hernia repair: outcomes, recurrence, and charge analysis. Surgery (United States) 160(6):1517–1527. https://doi.org/10.1016/J.SURG.2016.07.008
doi: 10.1016/J.SURG.2016.07.008
Shao JM, Ayuso SA, Deerenberg EB et al (2022) Biologic mesh is non-inferior to synthetic mesh in CDC class 1 & 2 open abdominal wall reconstruction. Am J Surg 223(2):375–379. https://doi.org/10.1016/J.AMJSURG.2021.05.019
doi: 10.1016/J.AMJSURG.2021.05.019
pubmed: 34140156
de Vries FEE, Hodgkinson JD, Claessen JJM et al (2020) Long-term outcomes after contaminated complex abdominal wall reconstruction. Hernia 24(3):459–468. https://doi.org/10.1007/S10029-020-02124-7
doi: 10.1007/S10029-020-02124-7
pubmed: 32078080
pmcid: 7210226
Atema JJ, Furnée EJ, Maeda Y et al (2017) Major complex abdominal wall repair in contaminated fields with use of a non-cross-linked biologic mesh: a dual-institutional experience. World J Surg 41(8):1993–1999. https://doi.org/10.1007/S00268-017-3962-2
doi: 10.1007/S00268-017-3962-2
pubmed: 28265733
pmcid: 5504255
Burger JWA, Luijendijk RW, Hop WCJ et al (2004) Long-term follow-up of a randomized controlled trial of suture versus mesh repair of incisional hernia. Ann Surg 240(4):578–585. https://doi.org/10.1097/01.SLA.0000141193.08524.E7
doi: 10.1097/01.SLA.0000141193.08524.E7
pubmed: 15383785
pmcid: 1356459
Kugler NW, Bobbs M, Webb T, Carver TW, Milia D, Paul JS (2016) A dual-stage approach to contaminated, high-risk ventral hernia repairs. J Surg Res 204(1):200–204. https://doi.org/10.1016/J.JSS.2016.04.065
doi: 10.1016/J.JSS.2016.04.065
pubmed: 27451887
Lipman J, Medalie D, Rosen MJ (2008) Staged repair of massive incisional hernias with loss of abdominal domain: a novel approach. Am J Surg 195(1):84–88. https://doi.org/10.1016/J.AMJSURG.2007.02.017
doi: 10.1016/J.AMJSURG.2007.02.017
pubmed: 18082547
van Rooijen MMJ, Tollens T, Jørgensen LN et al (2022) Slowly resorbable biosynthetic mesh: 2-year results in VHWG grade 3 hernia repair. Hernia 26(1):131–138. https://doi.org/10.1007/S10029-021-02453-1/FIGURES/4
doi: 10.1007/S10029-021-02453-1/FIGURES/4
pubmed: 34282506
van Rooijen MM, Jairam AP, Tollens T et al (2020) Outcomes of a new slowly resorbable biosynthetic mesh (Phasix™) in potentially contaminated incisional hernias: a prospective, multi-center, single-arm trial. Int J Surg 83:31–36. https://doi.org/10.1016/J.IJSU.2020.08.053
doi: 10.1016/J.IJSU.2020.08.053
pubmed: 32931978
Breuing K, Butler CE, Ferzoco S et al (2010) Incisional ventral hernias: Review of the literature and recommendations regarding the grading and technique of repair. Surgery 148(3):544–558. https://doi.org/10.1016/J.SURG.2010.01.008
doi: 10.1016/J.SURG.2010.01.008
pubmed: 20304452
Carbonell AM, Criss CN, Cobb WS, Novitsky YW, Rosen MJ (2013) Outcomes of synthetic mesh in contaminated ventral hernia repairs. J Am Coll Surg 217(6):991–998. https://doi.org/10.1016/J.JAMCOLLSURG.2013.07.382
doi: 10.1016/J.JAMCOLLSURG.2013.07.382
pubmed: 24045140
Rosen MJ, Krpata DM, Petro CC et al (2022) Biologic vs synthetic mesh for single-stage repair of contaminated ventral hernias: a randomized clinical trial. JAMA Surg. https://doi.org/10.1001/JAMASURG.2021.6902
doi: 10.1001/JAMASURG.2021.6902
pubmed: 36223140
pmcid: 8771431
Liang MK, Holihan JL, Itani K et al (2017) Ventral hernia management: expert consensus guided by systematic review. Ann Surg 265(1):80–89. https://doi.org/10.1097/SLA.0000000000001701
doi: 10.1097/SLA.0000000000001701
pubmed: 28009730
Otero J, Cox TC, Huntington CR et al (2018) Development of the carolinas equation for determining associated risks application and its effects on patient outcomes and potential financial savings in open ventral hernia repair. J Am Coll Surg 227(4):S98. https://doi.org/10.1016/J.JAMCOLLSURG.2018.07.199
doi: 10.1016/J.JAMCOLLSURG.2018.07.199
Nguyen DH, Nguyen MT, Askenasy EP, Kao LS, Liang MK (2014) Primary fascial closure with laparoscopic ventral hernia repair: systematic review. World J Surg 38(12):3097–3104. https://doi.org/10.1007/S00268-014-2722-9
doi: 10.1007/S00268-014-2722-9
pubmed: 25145817
Booth JH, Garvey PB, Baumann DP et al (2013) Primary fascial closure with mesh reinforcement is superior to bridged mesh repair for abdominal wall reconstruction. J Am Coll Surg 217(6):999–1009. https://doi.org/10.1016/J.JAMCOLLSURG.2013.08.015
doi: 10.1016/J.JAMCOLLSURG.2013.08.015
pubmed: 24083910
Maloney SR, Schlosser KA, Prasad T et al (2019) Twelve years of component separation technique in abdominal wall reconstruction. Surgery 166(4):435–444. https://doi.org/10.1016/J.SURG.2019.05.043
doi: 10.1016/J.SURG.2019.05.043
pubmed: 31358348
Deerenberg EB, Elhage SA, Shao JM et al (2021) The effects of preoperative botulinum toxin a injection on abdominal wall reconstruction. J Surg Res 260:251–258. https://doi.org/10.1016/J.JSS.2020.10.028
doi: 10.1016/J.JSS.2020.10.028
pubmed: 33360691
de Vries FEE, Atema JJ, Lapid O, Obdeijn MC, Boermeester MA (2017) Closed incision prophylactic negative pressure wound therapy in patients undergoing major complex abdominal wall repair. Hernia 21(4):583–589. https://doi.org/10.1007/S10029-017-1620-0/TABLES/2
doi: 10.1007/S10029-017-1620-0/TABLES/2
pubmed: 28534258
pmcid: 5517612
Ayuso SA, Elhage SA, Aladegbami BG et al (2022) Delayed primary closure (DPC) of the skin and subcutaneous tissues following complex, contaminated abdominal wall reconstruction (AWR): a propensity-matched study. Surg Endosc 36(3):2169–2177. https://doi.org/10.1007/S00464-021-08485-Z
doi: 10.1007/S00464-021-08485-Z
pubmed: 34018046
CDC, Oid, Ncezid, DHQP. (2020) 9 Surgical Site Infection (SSI) Event
Grove TN, Kontovounisios C, Montgomery A, Heniford BT, Windsor ACJ, Warren OJ (2015) Perioperative optimization in complex abdominal wall hernias: delphi consensus statement. BJS Open. 5(5):zrab082. https://doi.org/10.1093/BJSOPEN/ZRAB082
doi: 10.1093/BJSOPEN/ZRAB082
DeLancey JO, Blay E, Hewitt DB et al (2018) The effect of smoking on 30-day outcomes in elective hernia repair. Am J Surg 216(3):471–474. https://doi.org/10.1016/j.amjsurg.2018.03.004
doi: 10.1016/j.amjsurg.2018.03.004
pubmed: 29559083
pmcid: 6637424
Deerenberg EB, Shao JM, Elhage SA et al (2021) Pre-operative botulinum toxin a injection in complex abdominal wall reconstruction– a propensity-scored matched study. Am J Surg 222(3):638–642
doi: 10.1016/j.amjsurg.2021.01.010
pubmed: 33478721
Holihan JL, Nguyen DH, Nguyen MT, Mo J, Kao LS, Liang MK (2016) Mesh location in open ventral hernia repair: a systematic review and network meta-analysis. World J Surg 40(1):89–99. https://doi.org/10.1007/s00268-015-3252-9
doi: 10.1007/s00268-015-3252-9
pubmed: 26423675
Huntington CR, Cox TC, Blair LJ et al (2016) Biologic mesh in ventral hernia repair: outcomes, recurrence, and charge analysis. Surgery 160:1517–1527. https://doi.org/10.1016/j.surg.2016.07.008
doi: 10.1016/j.surg.2016.07.008
pubmed: 27528210
Hawn MT, Gray SH, Snyder CW, Graham LA, Finan KR, Vick CC (2011) Predictors of mesh explantation after incisional hernia repair. Am J Surg 202(1):28–33. https://doi.org/10.1016/J.AMJSURG.2010.10.011
doi: 10.1016/J.AMJSURG.2010.10.011
pubmed: 21741517
Altom LK, Graham LA, Gray SH, Snyder CW, Vick CC, Hawn MT (2012) Outcomes for incisional hernia repair in patients undergoing concomitant surgical procedures. Am Surg 78(2):243–249. https://doi.org/10.1177/000313481207800246
doi: 10.1177/000313481207800246
pubmed: 22369837
Cross W, Kumar A, Kowdley GC (2014) Biological mesh in contaminated fields-overuse without data: a systematic review of their use in abdominal wall reconstruction. Am Surg 80(1):3–8. https://doi.org/10.1177/000313481408000104
doi: 10.1177/000313481408000104
pubmed: 24401495
Kanters AE, Krpata DM, Blatnik JA, Novitsky YM, Rosen MJ (2012) Modified hernia grading scale to stratify surgical site occurrence after open ventral hernia repairs. J Am Coll Surg 215(6):787–793. https://doi.org/10.1016/J.JAMCOLLSURG.2012.08.012
doi: 10.1016/J.JAMCOLLSURG.2012.08.012
pubmed: 22999328
Harris HW, Primus F, Young C et al (2021) Preventing recurrence in clean and contaminated hernias using biologic versus synthetic mesh in ventral hernia repair. Ann Surg 273(4):648–655. https://doi.org/10.1097/SLA.0000000000004336
doi: 10.1097/SLA.0000000000004336
pubmed: 33443907
Albino FP, Patel KM, Nahabedian MY, Sosin M, Attinger CE, Bhanot P (2013) Does mesh location matter in abdominal wall reconstruction? A systematic review of the literature and a summary of recommendations. Plast Reconstr Surg 132(5):1295–1304. https://doi.org/10.1097/PRS.0B013E3182A4C393
doi: 10.1097/PRS.0B013E3182A4C393
pubmed: 24165612
Ayuso SA, Robinson JN, Colavita PD, Heniford BT (2021) Smoking, obesity, and the elective operation. Surg Clin North Am 101(6):981–993. https://doi.org/10.1016/J.SUC.2021.05.025
doi: 10.1016/J.SUC.2021.05.025
pubmed: 34774276
Huntington C, Gamble J, Blair L et al (2016) Quantification of the effect of diabetes mellitus on ventral hernia repair: results from two national registries. Am Surg 82(8):661–671. https://doi.org/10.1177/000313481608200822
doi: 10.1177/000313481608200822
pubmed: 27657579
Plymale MA, Davenport DL, Walsh-Blackmore S et al (2020) Costs and complications associated with infected mesh for ventral hernia repair. Surg Infect 21(4):343–348. https://doi.org/10.1089/SUR.2019.183
doi: 10.1089/SUR.2019.183
Holihan JL, Alawadi Z, Martindale RG et al (2015) Adverse events after ventral hernia repair: the vicious cycle of complications. J Am Coll Surg 221(2):478–485. https://doi.org/10.1016/J.JAMCOLLSURG.2015.04.026
doi: 10.1016/J.JAMCOLLSURG.2015.04.026
pubmed: 26206646
Rognoni C, Bassi UA, Cataldo M et al (2018) Budget impact analysis of a biosynthetic mesh for incisional hernia repair. Clin Ther 40(11):1830-1844.e4. https://doi.org/10.1016/J.CLINTHERA.2018.09.003
doi: 10.1016/J.CLINTHERA.2018.09.003
pubmed: 30348513
Liang MK, Bernardi K, Holihan JL et al (2018) Modifying risks in ventral hernia patients with prehabilitation: a randomized controlled trial. Ann Surg 268(4):674–680. https://doi.org/10.1097/SLA.0000000000002961
doi: 10.1097/SLA.0000000000002961
pubmed: 30048306
Cox TC, Blair LJ, Huntington CR et al (2016) The cost of preventable comorbidities on wound complications in open ventral hernia repair. J Surg Res 206(1):214–222. https://doi.org/10.1016/J.JSS.2016.08.009
doi: 10.1016/J.JSS.2016.08.009
pubmed: 27916364
Ayuso SA, Colavita PD, Augenstein VA et al (2022) Nationwide increase in component separation without concomitant rise in readmissions: a nationwide readmissions database analysis. Surgery 171(3):799–805. https://doi.org/10.1016/J.SURG.2021.09.012
doi: 10.1016/J.SURG.2021.09.012
pubmed: 34756604
Elhage SA, Deerenberg EB, Shao JM, Augenstein VA, Heniford BT (2020) The use of botulinum toxin A in chemical component separation: a review of techniques and outcomes. Plastic Aesthetic Res 7:16. https://doi.org/10.20517/2347-9264.2020.03
doi: 10.20517/2347-9264.2020.03
Deerenberg EB, Shao JM, Elhage SA et al (2021) Preoperative botulinum toxin A injection in complex abdominal wall reconstruction- a propensity-scored matched study. Am J Surg 222(3):638–642. https://doi.org/10.1016/J.AMJSURG.2021.01.010
doi: 10.1016/J.AMJSURG.2021.01.010
pubmed: 33478721
Maloney SR, Augenstein VA, Oma E et al (2019) The use of component separation during abdominal wall reconstruction in contaminated fields: a case-control analysis. Am J Surg 218(6):1096–1101. https://doi.org/10.1016/J.AMJSURG.2019.10.019
doi: 10.1016/J.AMJSURG.2019.10.019
pubmed: 31630827
Schlosser KA, Maloney SR, Gbozah K et al (2020) The impact of weight change on intra-abdominal and hernia volumes. Surgery 167(5):876–882. https://doi.org/10.1016/J.SURG.2020.01.007
doi: 10.1016/J.SURG.2020.01.007
pubmed: 32151368