Cancer stem cells in esophageal squamous cell carcinoma.
Cancer stem cells
Esophageal squamous cell carcinoma
Therapeutic resistance
Journal
Pathology, research and practice
ISSN: 1618-0631
Titre abrégé: Pathol Res Pract
Pays: Germany
ID NLM: 7806109
Informations de publication
Date de publication:
Sep 2022
Sep 2022
Historique:
received:
21
06
2022
revised:
21
07
2022
accepted:
26
07
2022
pubmed:
5
8
2022
medline:
26
10
2022
entrez:
4
8
2022
Statut:
ppublish
Résumé
Esophageal squamous cell carcinoma (ESCC) is one of the most intractable challenges among human diseases with poor prognosis and shortness of effective therapeutic options. Cancer stem cells (CSCs), a tumor sub-population, are considered the cause of tumor growth, differentiation, metastasis and therapeutic resistance, etc. In this review, we discuss the known methods for isolation and verification of ESCC CSCs, the biomarkers of ESCC CSCs and their significance in diagnosis and prognosis. Then we review the ESCC CSC signaling pathway and therapeutic resistance. In pace with the detailed studies of ESCC CSCs increasing, treatment strategies of ESCC based on CSCs are becoming more promising.
Identifiants
pubmed: 35926434
pii: S0344-0338(22)00287-4
doi: 10.1016/j.prp.2022.154043
pii:
doi:
Substances chimiques
Biomarkers, Tumor
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
154043Informations de copyright
Copyright © 2022. Published by Elsevier GmbH.
Déclaration de conflit d'intérêts
Conflict of interest The authors declare that they have no conflict of interest.