Biomechanical Morphing for Personalized Fitting of Scoliotic Torso Skeleton Models.
biomechanical models
geometry fitting
low-dose x-rays
modeling of the torso
scoliosis
Journal
Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
Titre abrégé: Front Bioeng Biotechnol
Pays: Switzerland
ID NLM: 101632513
Informations de publication
Date de publication:
2022
2022
Historique:
received:
16
05
2022
accepted:
23
06
2022
entrez:
5
8
2022
pubmed:
6
8
2022
medline:
6
8
2022
Statut:
epublish
Résumé
The use of patient-specific biomechanical models offers many opportunities in the treatment of adolescent idiopathic scoliosis, such as the design of personalized braces. The first step in the development of these patient-specific models is to fit the geometry of the torso skeleton to the patient's anatomy. However, existing methods rely on high-quality imaging data. The exposure to radiation of these methods limits their applicability for regular monitoring of patients. We present a method to fit personalized models of the torso skeleton that takes as input biplanar low-dose radiographs. The method morphs a template to fit annotated points on visible portions of the spine, and it relies on a default biomechanical model of the torso for regularization and robust fitting of hardly visible parts of the torso skeleton, such as the rib cage. The proposed method provides an accurate and robust solution to obtain personalized models of the torso skeleton, which can be adopted as part of regular management of scoliosis patients. We have evaluated the method on ten young patients who participated in our study. We have analyzed and compared clinical metrics on the spine and the full torso skeleton, and we have found that the accuracy of the method is at least comparable to other methods that require more demanding imaging methods, while it offers superior robustness to artifacts such as interpenetration of ribs. Normal-dose X-rays were available for one of the patients, and for the other nine we acquired low-dose X-rays, allowing us to validate that the accuracy of the method persisted under less invasive imaging modalities.
Identifiants
pubmed: 35928945
doi: 10.3389/fbioe.2022.945461
pii: 945461
pmc: PMC9343806
doi:
Types de publication
Journal Article
Langues
eng
Pagination
945461Informations de copyright
Copyright © 2022 Koutras, Shayestehpour, Pérez, Wong, Rasmussen, Tournier, Nesme and Otaduy.
Déclaration de conflit d'intérêts
Authors MT and MN were employed by the company AnatoScope SA. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
J Clin Med. 2018 Jun 04;7(6):
pubmed: 29867010
Med Biol Eng Comput. 2007 Jun;45(6):591-602
pubmed: 17530454
Int J Numer Method Biomed Eng. 2021 Oct;37(10):e3503
pubmed: 34114367
Acta Radiol Open. 2021 Sep 25;10(9):20584601211043258
pubmed: 34594575
Med Biol Eng Comput. 2010 Aug;48(8):821-8
pubmed: 20414812
J Child Orthop. 2013 Feb;7(1):3-9
pubmed: 24432052
Comput Methods Programs Biomed. 2021 Mar;200:105833
pubmed: 33250283
Spine Deform. 2014 Jan;2(1):10-27
pubmed: 27927438
Eur Spine J. 2011 Jul;20(7):1095-105
pubmed: 21308473
Med Biol Eng Comput. 2005 Mar;43(2):258-64
pubmed: 15865137
Med Image Anal. 2009 Aug;13(4):543-63
pubmed: 19525140
Comput Methods Programs Biomed. 2021 Oct;210:106360
pubmed: 34517183
Ann Transl Med. 2020 Jan;8(2):28
pubmed: 32055619
Phys Med Biol. 2014 Mar 21;59(6):1485-99
pubmed: 24594843
Stud Health Technol Inform. 2007;125:13-8
pubmed: 17377224
Spine J. 2017 Nov;17(11):1755-1764
pubmed: 28673824
Int J Environ Res Public Health. 2021 Aug 01;18(15):
pubmed: 34360445
IEEE Trans Biomed Eng. 2004 May;51(5):838-46
pubmed: 15132511
Clin Med Pediatr. 2009 Mar 04;3:39-44
pubmed: 23818793
Scoliosis Spinal Disord. 2017 Jul 23;12:24
pubmed: 28770254
Spine J. 2014 Aug 1;14(8):1432-9
pubmed: 24275616
Spine (Phila Pa 1976). 2012 Apr 20;37(9):E540-8
pubmed: 22020591
Eur Spine J. 2019 Apr;28(4):658-664
pubmed: 30382429
Med Eng Phys. 2019 Jun;68:35-45
pubmed: 31010615
Eur Spine J. 2016 Oct;25(10):3056-3064
pubmed: 26861663
Med Image Anal. 2012 Apr;16(3):662-74
pubmed: 21126904
Spine (Phila Pa 1976). 2007 Jan 1;32(1):106-12
pubmed: 17202900
Comput Methods Programs Biomed. 2020 Dec;197:105741
pubmed: 32961386
Clin Biomech (Bristol, Avon). 2016 Nov;39:25-31
pubmed: 27639485
IEEE Trans Biomed Eng. 2007 Jul;54(7):1356-8
pubmed: 17605369
J Biomech. 2008;41(3):706-10
pubmed: 17981286
J Biomech. 2020 Mar 26;102:109305
pubmed: 31471110
Phys Med Biol. 2014 Jan 20;59(2):311-26
pubmed: 24351846
Med Eng Phys. 2013 Nov;35(11):1651-8
pubmed: 23830740
Med Eng Phys. 2009 Jul;31(6):681-7
pubmed: 19230743
Eur Spine J. 2000 Jun;9(3):185-90
pubmed: 10905434
Int J Comput Assist Radiol Surg. 2010 Mar;5(2):111-24
pubmed: 20033504
Comput Methods Programs Biomed. 2021 Aug;207:106125
pubmed: 34020374
Eur Spine J. 2013 Nov;22(11):2360-71
pubmed: 23443679
J Biomech. 2016 Apr 11;49(6):959-966
pubmed: 26684431
J Pediatr Orthop. 2021 Jul 1;41(6):327-332
pubmed: 34096545
Eur Spine J. 2016 Oct;25(10):3049-3055
pubmed: 26968874
J Biomech Eng. 2009 Apr;131(4):041007
pubmed: 19275436
Spine (Phila Pa 1976). 2021 Jan 1;46(1):9-16
pubmed: 32991513
J Biomech. 2007;40(6):1219-27
pubmed: 16901492
IEEE Trans Biomed Eng. 2011 May;58(5):1135-46
pubmed: 19789100
Comput Methods Biomech Biomed Engin. 2017 Jan;20(1):1-15
pubmed: 27315668
Comput Methods Biomech Biomed Engin. 2021 Jun;24(8):874-882
pubmed: 33295806
IEEE Trans Biomed Eng. 2015 Nov;62(11):2709-16
pubmed: 26080375
Spine J. 2020 Jun;20(6):947-955
pubmed: 31972303
Technol Cancer Res Treat. 2017 Feb;16(1):99-111
pubmed: 26206767
Comput Methods Programs Biomed. 2019 Aug;177:47-56
pubmed: 31319960
Clin Spine Surg. 2017 Mar;30(2):85-89
pubmed: 28207617