First report of auxiliary liver transplantation for severe cholangiopathy after SARS-CoV-2 respiratory infection.

COVID-19 pneumonia cholestasis liver regeneration living donor liver transplantation subacute liver failure therapeutic plasma exchange

Journal

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
ISSN: 1600-6143
Titre abrégé: Am J Transplant
Pays: United States
ID NLM: 100968638

Informations de publication

Date de publication:
12 2022
Historique:
revised: 20 07 2022
received: 13 06 2022
accepted: 02 08 2022
pubmed: 6 8 2022
medline: 6 12 2022
entrez: 5 8 2022
Statut: ppublish

Résumé

Post-coronavirus disease 2019 (COVID-19) cholangiopathy (PCC) is a new entity observed in patients recovering from severe COVID-19 pneumonia. Most patients recover with cholestasis improving over a period of time. In some patients, cholestasis is severe and persists or progresses to liver failure necessitating liver transplant. We present a previously healthy 50-year-old man who developed PCC with peak total bilirubin of 42.4 mg/dl and did not improve with medical management. He underwent living donor auxiliary right lobe liver transplantation. He recovered well after transplant and remains asymptomatic at 6 months follow-up with good graft function and recovering function in native liver remnant.

Identifiants

pubmed: 35929565
doi: 10.1111/ajt.17165
pmc: PMC9538267
pii: S1600-6135(23)00067-9
doi:

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

3143-3145

Informations de copyright

© 2022 The American Society of Transplantation and the American Society of Transplant Surgeons.

Références

Transplant Proc. 2021 May;53(4):1132-1137
pubmed: 33846012
Liver Transpl. 2016 Sep;22(9):1265-74
pubmed: 27357489
BMJ Case Rep. 2021 Aug 26;14(8):
pubmed: 34446515
Am J Gastroenterol. 2021 Jul 1;116(7):1414-1425
pubmed: 33993134
Am J Gastroenterol. 2021 May 1;116(5):1077-1082
pubmed: 33464757
J Hepatol. 2021 Oct;75(4):989-990
pubmed: 33753153

Auteurs

Mohamed Rela (M)

The Institute of Liver Disease & Transplantation, Dr Rela Institute & Medical Centre, Bharath Institute of Higher Education and Research, Chennai, India.

Muthukumarassamy Rajakannu (M)

The Institute of Liver Disease & Transplantation, Dr Rela Institute & Medical Centre, Bharath Institute of Higher Education and Research, Chennai, India.

Fadl H Veerankutty (FH)

The Institute of Liver Disease & Transplantation, Dr Rela Institute & Medical Centre, Bharath Institute of Higher Education and Research, Chennai, India.

Mukul Vij (M)

The Institute of Liver Disease & Transplantation, Dr Rela Institute & Medical Centre, Bharath Institute of Higher Education and Research, Chennai, India.

Ashwin Rammohan (A)

The Institute of Liver Disease & Transplantation, Dr Rela Institute & Medical Centre, Bharath Institute of Higher Education and Research, Chennai, India.

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Classifications MeSH