Staphylococcus aureus lineages associated with a free-ranging population of the fruit bat Pteropus livingstonii retained over 25 years in captivity.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
05 08 2022
Historique:
received: 28 02 2022
accepted: 01 08 2022
entrez: 5 8 2022
pubmed: 6 8 2022
medline: 10 8 2022
Statut: epublish

Résumé

Conservation of endangered species has become increasingly complex, and costly interventions to protect wildlife require a robust scientific evidence base. This includes consideration of the role of the microbiome in preserving animal health. Captivity introduces stressors not encountered in the wild including environmental factors and exposure to exotic species, humans and antimicrobial drugs. These stressors may perturb the microbiomes of wild animals, with negative consequences for their health and welfare and hence the success of the conservation project, and ultimately the risk of release of non-native organisms into native ecosystems. We compared the genomes of Staphylococcus aureus colonising critically endangered Livingstone's fruit bats (Pteropus livingstonii) which have been in a captive breeding programme for 25 years, with those from bats in the endemic founder population free ranging in the Comoros Republic. Using whole genome sequencing, we compared 47 isolates from captive bats with 37 isolates from those free ranging in the Comoros Republic. Our findings demonstrate unexpected resilience in the bacteria carried, with the captive bats largely retaining the same two distinctive lineages carried at the time of capture. In addition, we found evidence of genomic changes which suggest specific adaptations to the bat host.

Identifiants

pubmed: 35931727
doi: 10.1038/s41598-022-17835-3
pii: 10.1038/s41598-022-17835-3
pmc: PMC9355961
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

13457

Informations de copyright

© 2022. The Author(s).

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Auteurs

Kay Fountain (K)

Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK. kay.fountain21@gmail.com.

Alberto Barbon (A)

North of England Zoological Society (Chester Zoo), Caughall Road, Upton by Chester, Chester, Cheshire, CH2 1LH, UK.

Marjorie J Gibbon (MJ)

Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK.

David H Lloyd (DH)

Department of Clinical Science and Services, Royal Veterinary College, North Mymms, Hatfield, Hertfordshire, AL9 7TA, UK.

Anette Loeffler (A)

Department of Clinical Science and Services, Royal Veterinary College, North Mymms, Hatfield, Hertfordshire, AL9 7TA, UK.

Edward J Feil (EJ)

Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK.

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