Facilitators for retaining men who have sex with men in pre-exposure prophylaxis care in real world clinic settings within the United States.
Medication adherence
Persistence
PrEP continuum
Pre-exposure prophylaxis
Retention in care
Journal
BMC infectious diseases
ISSN: 1471-2334
Titre abrégé: BMC Infect Dis
Pays: England
ID NLM: 100968551
Informations de publication
Date de publication:
05 Aug 2022
05 Aug 2022
Historique:
received:
26
02
2022
accepted:
29
07
2022
entrez:
5
8
2022
pubmed:
6
8
2022
medline:
10
8
2022
Statut:
epublish
Résumé
Pre-exposure prophylaxis (PrEP) can significantly reduce HIV acquisition especially among communities with high HIV prevalence, including men who have sex with men (MSM). Much research has been finding suboptimal PrEP persistence; however, few studies examine factors that enhance PrEP persistence in real-world settings. We interviewed 33 patients who identified as MSM at three different PrEP clinics in three regions of the U.S. (Northeast, South, Midwest). Participants were eligible if they took PrEP and had been retained in care for a minimum of 6 months. Interviews explored social, structural, clinic-level and behavioral factors that influencing PrEP persistence. Through thematic analysis we identified the following factors as promoting PrEP persistence: (1) navigation to reduce out-of-pocket costs of PrEP (structural), (2) social norms that support PrEP use (social), (3) access to LGBTQ + affirming medical providers (clinical), (4) medication as part of a daily routine (behavioral), and (5) facilitation of sexual health agency (belief). In this sample, persistence in PrEP care was associated with structural and social supports as well as a high level of perceived internal control over protecting their health by taking PrEP. Patients might benefit from increased access, LGBTQ + affirming medical providers, and communications that emphasize PrEP can promote sexual health.
Sections du résumé
BACKGROUND
BACKGROUND
Pre-exposure prophylaxis (PrEP) can significantly reduce HIV acquisition especially among communities with high HIV prevalence, including men who have sex with men (MSM). Much research has been finding suboptimal PrEP persistence; however, few studies examine factors that enhance PrEP persistence in real-world settings.
METHODS
METHODS
We interviewed 33 patients who identified as MSM at three different PrEP clinics in three regions of the U.S. (Northeast, South, Midwest). Participants were eligible if they took PrEP and had been retained in care for a minimum of 6 months. Interviews explored social, structural, clinic-level and behavioral factors that influencing PrEP persistence.
RESULTS
RESULTS
Through thematic analysis we identified the following factors as promoting PrEP persistence: (1) navigation to reduce out-of-pocket costs of PrEP (structural), (2) social norms that support PrEP use (social), (3) access to LGBTQ + affirming medical providers (clinical), (4) medication as part of a daily routine (behavioral), and (5) facilitation of sexual health agency (belief).
DISCUSSION
CONCLUSIONS
In this sample, persistence in PrEP care was associated with structural and social supports as well as a high level of perceived internal control over protecting their health by taking PrEP. Patients might benefit from increased access, LGBTQ + affirming medical providers, and communications that emphasize PrEP can promote sexual health.
Identifiants
pubmed: 35931953
doi: 10.1186/s12879-022-07658-y
pii: 10.1186/s12879-022-07658-y
pmc: PMC9354303
doi:
Substances chimiques
Anti-HIV Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
673Subventions
Organisme : NIMH NIH HHS
ID : R25 MH083620
Pays : United States
Organisme : National Institutes of Mental Health
ID : 5R01MH114657-02
Organisme : Providence/Boston Center for AIDS Research
ID : P30AI042853
Organisme : NIMH NIH HHS
ID : K23 MH124539
Pays : United States
Organisme : National Institutes of Mental Health
ID : R25MH083620
Organisme : NIMH NIH HHS
ID : L30 MH123946
Pays : United States
Organisme : NIMH NIH HHS
ID : K23MH124539-01A1
Pays : United States
Informations de copyright
© 2022. The Author(s).
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