GRADE Guidance 34: update on rating imprecision using a minimally contextualized approach.
GRADE
Guideline
Imprecision
Minimally contextualized approach
Systematic review
Journal
Journal of clinical epidemiology
ISSN: 1878-5921
Titre abrégé: J Clin Epidemiol
Pays: United States
ID NLM: 8801383
Informations de publication
Date de publication:
10 2022
10 2022
Historique:
received:
01
12
2021
revised:
01
03
2022
accepted:
25
07
2022
pubmed:
8
8
2022
medline:
17
12
2022
entrez:
7
8
2022
Statut:
ppublish
Résumé
The aim of this study is to provide updated guidance on when The Grading of Recommendations Assessment, Development and Evaluation (GRADE) users should consider rating down more than one level for imprecision using a minimally contextualized approach. Based on the first GRADE guidance addressing imprecision rating in 2011, a project group within the GRADE Working Group conducted iterative discussions and presentations at GRADE Working Group meetings to produce this guidance. GRADE suggests aligning imprecision criterion for systematic reviews and guidelines using the approach that relies on thresholds and confidence intervals (CI) of absolute effects as a primary criterion for imprecision rating (i.e., CI approach). Based on the CI approach, when a CI appreciably crosses the threshold(s) of interest, one should consider rating down two or three levels. When the CI does not cross the threshold(s) and the relative effect is large, one should implement the optimal information size (OIS) approach. If the sample size of the meta-analysis is far less than the OIS, one should consider rating down more than one level for imprecision. GRADE provides updated guidance for imprecision rating in a minimally contextualized approach, with a focus on the circumstances in which one should seriously consider rating down two or three levels for imprecision.
Identifiants
pubmed: 35934265
pii: S0895-4356(22)00187-1
doi: 10.1016/j.jclinepi.2022.07.014
pii:
doi:
Types de publication
Meta-Analysis
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
216-224Informations de copyright
Copyright © 2022 The Author(s). Published by Elsevier Inc. All rights reserved.