Multiwalled Carbon Nanotubes as Nanomaterial Tool in the Management of Prostate Cancer: A Possible Nanoformulation Approach.

Carbon nanotubes Drug delivery In silico studies Prostate cancer

Journal

Advanced pharmaceutical bulletin
ISSN: 2228-5881
Titre abrégé: Adv Pharm Bull
Pays: Iran
ID NLM: 101578021

Informations de publication

Date de publication:
May 2022
Historique:
received: 02 11 2020
revised: 10 04 2021
accepted: 27 09 2021
entrez: 8 8 2022
pubmed: 9 8 2022
medline: 9 8 2022
Statut: ppublish

Résumé

Prostate cancer (PCa) is one of the leading diseases in men all over the world caused due to over-expression of prostate-specific membrane antigen (PSMA). Currently, the detection and targeting of PCa is one of the major challenges in the prostate gland. Therefore, Bruton tyrosine kinase inhibitor molecules like ibrutinib (Ibr) loaded with nanomaterials like multi-walled carbon nanotubes (MWCNTs), which has good physico-chemical properties may be the best regimen to treat PCa. In this strategy, the chemically modified MWCNTs have excellent 'Biosensing' properties makes it easy for detecting PCa without fluorescent agent and thus targets particular site of PCa. In the present study, Ibr/MWCNTs conjugated with T

Identifiants

pubmed: 35935048
doi: 10.34172/apb.2022.053
pmc: PMC9348525
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

509-514

Informations de copyright

©2022 The Authors.

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Auteurs

Raja Murugesan (R)

Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty, India.

Raman Sureshkumar (R)

Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty, India.

Arun Radhakrishnan (A)

Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty, India.

Srikanth Jupudi (S)

Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty, India.

Manisha Chennu (M)

Department of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty, India.

Classifications MeSH